scholarly journals Effect of Omeprazole on the Phosphate-Binding Capacity of Calcium Carbonate

Nephron ◽  
1995 ◽  
Vol 69 (1) ◽  
pp. 89-90 ◽  
Author(s):  
P. Osler ◽  
P. Raniga ◽  
K. Farrington
Keyword(s):  
Calcium Carbonate ◽  
Binding Capacity ◽  
Phosphate Binding

Comparison of the Effects of Ca-Mg Carbonate Chewable Tablets with Calcium Carbonate Tablets on Phosphate Binding in Patients on Hemodialysis Taking H2-R Blockers

2019 ◽  
Vol 26 (1) ◽  
pp. 43-49
Author(s):  
Bani Younes , Moh'd Nour Mahmoud ◽  
Hadad , Ayham ◽  
Al Rabadi , Katebh ◽  
Al Hindwai , Mahmoud ◽  
Al Maita , Mahmoud Hammad
Keyword(s):  
Calcium Carbonate ◽  
Phosphate Binding ◽  
Chewable Tablets

scholarly journals A comparison between the combined effect of calcium carbonate with sucroferric oxyhydroxide and other phosphate binders: an in vitro and in vivo experimental study

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Atsushi Yaguchi ◽  
Kenji Akahane ◽  
Kumi Tsuchioka ◽  
Saori Yonekubo ◽  
Shota Yamamoto ◽  
...  
Keyword(s):  
Calcium Carbonate ◽  
Lanthanum Carbonate ◽  
Combined Effect ◽  
Ferric Citrate ◽  
Phosphate Binders ◽  
Phosphate Solution ◽  
Phosphate Binding ◽  
Sevelamer Hydrochloride

Abstract Background Approximately 30% of patients on dialysis received combination therapy for their phosphate binder prescription; however, few studies for combined effects of phosphate binders are reported. For the purpose of evaluating the efficacy of combination therapy, we compared the efficacy of sucroferric oxyhydroxide (PA21) combined with calcium carbonate with that of lanthanum carbonate hydrate, sevelamer hydrochloride, and ferric citrate hydrate combined with calcium carbonate. Methods For in vitro studies, calcium carbonate and the other phosphate binders alone or in combination were stirred in phosphate solution at pH 2–8 for 2 h. After centrifuging the suspension, the phosphorus level in the supernatant was determined. For in vivo studies, rats were orally administered calcium carbonate and the other phosphate binders (except for sevelamer hydrochloride) alone or in combination, followed by oral administration of phosphate solution adjusted to pH 2 or 7. Serum samples were collected from the rats at predetermined timepoints and the serum phosphorus levels were determined and analyzed using a two-way analysis of variance. Results In the in vitro study, the measured phosphate-binding capacity of combining sevelamer hydrochloride, PA21, and lanthanum carbonate hydrate with calcium carbonate was approximately equal to or greater than the theoretical values under most conditions. Furthermore, these combined effects were insensitive to pH in that order. The measured phosphate-binding capacity of ferric citrate hydrate combined with calcium carbonate was smaller than the theoretical values, and the combination did not exhibit efficacy under any of the tested conditions. In the in vivo study, the combined effect of PA21 and calcium carbonate at both pH values and that of lanthanum carbonate hydrate and calcium carbonate at pH 2 were additive. In contrast, the combined effect of lanthanum carbonate hydrate and calcium carbonate at pH 7 and that of ferric citrate hydrate and calcium carbonate at pH 2 were antagonistic. Conclusions These results suggest that coadministration of PA21 and calcium carbonate showed good and relatively stable efficacy throughout the range of the gastrointestinal pH and that combining lanthanum carbonate hydrate and ferric citrate hydrate with calcium carbonate may not produce the expected efficacy under certain conditions.

Development of exobiopolymer-based biosensor for detection of phosphate in water

2013 ◽  
Vol 68 (12) ◽  
pp. 2619-2625 ◽  
Author(s):  
Taranpreet Kaur ◽  
Abhijit Ganguli ◽  
Moushumi Ghosh
Keyword(s):  
Limit Of Detection ◽  
Detection System ◽  
Binding Capacity ◽  
Phosphate Binding ◽  
Limit Of Quantification ◽  
Molybdenum Blue ◽  
Coated Membranes ◽  
Transposon Tn5 Mutagenesis ◽  
Acinetobacter Sp ◽  
High Phosphate

The present study was conducted to develop a biosensor by exploiting phosphate-binding capacity of exobiopolymer (EBP) produced by Acinetobacter sp. An environmental isolate of EBP-producing Acinetobacter sp. was subjected to transposon (Tn5) mutagenesis to overproduce EBP and afford improved phosphate selectivity. A mutant producing the highest amount of EBP with high phosphate-binding capacity was selected for biosensor probe fabrication. Phosphate samples were filtered through EBP-coated membranes and phosphate retained on membranes was determined by molybdenum blue method. The color produced was read using a LED 690 nm/photodiode detection system linked to an amplifier and signals were converted to appropriate phosphate concentrations. The biosensor had a limit of detection of 0.5 mg/L and a limit of quantification 1 mg/L. The biosensor as well as the probe were found to be stable for at least 28 days. In conclusion, we believe that the biosensor may have applications in monitoring of wastewater and environmental samples. Further, the enrichment of phosphate levels by EBP can help in analysis of very low phosphate concentrations.

Phosphate binding capacity of ferrihydrite vs calcium acetate in rats

1996 ◽  
Vol 27 (4) ◽  
pp. A12
Author(s):  
L.W. Peck ◽  
C.M. Weaver ◽  
H.M. Magnusen ◽  
B.R. Martin ◽  
D.G. Shulze ◽  
...  
Keyword(s):  
Binding Capacity ◽  
Calcium Acetate ◽  
Phosphate Binding

Ranitidine reduces phosphate binding in dialysis patients receiving calcium carbonate

1996 ◽  
Vol 11 (5) ◽  
pp. 851-853 ◽  
Author(s):  
C. C. Tan ◽  
P. N. Harden ◽  
R. S. C. Rodger ◽  
P. A. Rowe ◽  
R. J. Spooner ◽  
...  
Keyword(s):  
Calcium Carbonate ◽  
Phosphate Binding ◽  
Dialysis Patients

scholarly journals Chloride Resistance of Portland Cement-Based Mortar Incorporating High Aluminate Cement and Calcium Carbonate

Materials ◽  
2020 ◽  
Vol 13 (2) ◽  
pp. 359 ◽  
Author(s):  
Yunsu Lee ◽  
Seungmin Lim ◽  
Hanseung Lee
Keyword(s):  
Diffusion Coefficient ◽  
Calcium Carbonate ◽  
Pore Volume ◽  
Binding Capacity ◽  
Chloride Diffusion ◽  
Chloride Diffusion Coefficient ◽  
Chloride Binding ◽  
Chloride Resistance ◽  
Aluminate Cement ◽  
Capillary Pore

Whether chloride resistance is highly influenced by chloride binding capacity remains unknown. In this study, the chloride resistance of Portland cement-based mortar incorporating aluminate cement and calcium carbonate was investigated considering the chloride binding capacity, pore structures and chloride diffusion coefficient from non-steady state chloride migration and natural chloride diffusion. The cement hydrates were investigated using X-ray diffraction and thermogravimetric analysis. The chloride binding capacity was evaluated based on the chloride adsorption from the solutions using the adsorption isotherm. The aluminate cement, as an available alumina source, can stimulate the formulation of layered double hydroxides, which in turn can increase the chloride binding capacity. The results of mercury intrusion porosimetry show that non-substituted (control) and substituted (only aluminate cement) specimens have capillary pore volume 8.9 vol % and 8.2 vol %, respectively. However, the specimen substituted with aluminate cement and calcium carbonate shows a higher capillary volume (12.9 vol %), which correlates with the chloride diffusion coefficient. Although the specimen substituted with calcium carbonate has a higher chloride binding capacity than the control, it does not necessarily affect the decrease in the chloride diffusion coefficient. The capillary pore volume can affect not only the chloride diffusion but also the chloride adsorption.

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