Differential Expression of Matrix Metalloproteinases and Tissue Inhibitors and Extracellular Matrix Remodeling in Aortic Regurgitant Hearts

Cardiology ◽  
2009 ◽  
Vol 113 (3) ◽  
pp. 161-168 ◽  
Author(s):  
Sharada L. Truter ◽  
Daniel F. Catanzaro ◽  
Phyllis G. Supino ◽  
Anuj Gupta ◽  
John Carter ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Matrix Metalloproteinases ◽  
Differential Expression ◽  
Extracellular Matrix Remodeling ◽  
Matrix Remodeling ◽  
Tissue Inhibitors

scholarly journals A Potential Role for MMPs during the Formation of Non-Neurogenic Placodes

2018 ◽  
Vol 6 (3) ◽  
pp. 20 ◽  
Author(s):  
Paige Drake ◽  
Tamara Franz-Odendaal
Keyword(s):  
Extracellular Matrix ◽  
Mammary Gland ◽  
Matrix Metalloproteinases ◽  
Potential Role ◽  
Critical Role ◽  
Extracellular Matrix Remodeling ◽  
Matrix Remodeling ◽  
Lens Development ◽  
Cell Behaviors ◽  
Placode Formation

The formation of non-neurogenic placodes is critical prior to the development of several epithelial derivatives (e.g., feathers, teeth, etc.) and their development frequently involves morphogenetic proteins (or morphogens). Matrix metalloproteinases (MMPs) are important enzymes involved in extracellular matrix remodeling, and recent research has shown that the extracellular matrix (ECM) can modulate morphogen diffusion and cell behaviors. This review summarizes the known roles of MMPs during the development of non-neurogenic structures that involve a placodal stage. Specifically, we discuss feather, hair, tooth, mammary gland and lens development. This review highlights the potential critical role MMPs may play during placode formation in these systems.

scholarly journals Biglycan fragmentation in pathologies associated with extracellular matrix remodeling by matrix metalloproteinases

2013 ◽  
Vol 6 (1) ◽  
Author(s):  
Federica Genovese ◽  
Natasha Barascuk ◽  
Lise Larsen ◽  
Martin Røssel Larsen ◽  
Arkadiusz Nawrocki ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Matrix Metalloproteinases ◽  
Extracellular Matrix Remodeling ◽  
Matrix Remodeling
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