Perfusion Pressure, Proteinuria and the Isolated Rat Kidney-Comment

Nephron ◽  
1993 ◽  
Vol 63 (1) ◽  
pp. 124-124 ◽  
Author(s):  
L.O. Simpson
Keyword(s):  
Perfusion Pressure ◽  
Rat Kidney ◽  
Isolated Rat Kidney ◽  
Isolated Rat

A servo-system for constant pressure perfusion of the isolated rat kidney

1986 ◽  
Vol 250 (4) ◽  
pp. F744-F748
Author(s):  
R. C. Scaduto ◽  
A. C. Schoolwerth
Keyword(s):  
Perfusion Pressure ◽  
Rat Kidney ◽  
Servo System ◽  
Technical Difficulty ◽  
Perfusion Flow ◽  
Isolated Rat Kidney ◽  
Rapid Changes ◽  
Analog Circuitry ◽  
Perfusion Flow Rate ◽  
Isolated Rat

A technical difficulty in perfusion of the isolated rat kidney has been the regulation of perfusion pressure. Since perfusion pressure is an important determinant of renal function, this parameter should be well regulated for experimental consistency. A servo-system is described that uses analog circuitry to calculate and maintain the cannula tip pressure for perfusion of the isolated kidney. The system is sufficiently responsive to maintain a constant perfusion pressure during the rapid changes in renal resistance caused by addition of angiotensin II or epinephrine to the perfusate. Analog outputs are provided for the recording of perfusion flow rate, perfusion pressure, and renal resistance.

Inhibition of Renin Secretion in the Isolated Rat Kidney by Antidiuretic Hormone

1975 ◽  
Vol 49 (1) ◽  
pp. 73-76 ◽  
Author(s):  
R. Vandongen
Keyword(s):  
Antidiuretic Hormone ◽  
Calcium Ions ◽  
Perfusion Pressure ◽  
Direct Action ◽  
Rat Kidney ◽  
Renal Perfusion ◽  
Renin Secretion ◽  
Renal Perfusion Pressure ◽  
Isolated Rat Kidney ◽  
Isolated Rat

1. The effect of antidiuretic hormone (ADH) on isoprenaline-stimulated renin secretion was examined in the isolated rat kidney perfused with modified Krebs-Ringer saline. 2. Intrarenal infusion of ADH effectively prevented stimulation of renin secretion by isoprenaline whilst increasing renal perfusion pressure. 3. The exclusion of calcium ions from the perfusion medium abolished the vasoconstrictor effect of ADH and attenuated the inhibitory effect of ADH on isoprenaline-stimulated renin secretion. However, significant suppression of renin secretion was still apparent compared with experiments where isoprenaline was infused alone. 4. These observations indicate that ADH inhibits renin secretion and that this is effected by a direct action on the kidney. Although this may be partly mediated by the rise in renal perfusion pressure, an additional direct effect of ADH on the renin-producing cell, which is dependent on the availability of calcium ions, is proposed.

Relationship between perfusion pressure and renin release in the isolated rat kidney

1975 ◽  
Vol 360 (3) ◽  
pp. 255-266 ◽  
Author(s):  
H. Zschiedrich ◽  
K. G. Hofbauer ◽  
G. D. Baron ◽  
E. Hackenthal ◽  
F. Gross
Keyword(s):  
Perfusion Pressure ◽  
Rat Kidney ◽  
Renin Release ◽  
Isolated Rat Kidney ◽  
Isolated Rat

scholarly journals Flow-induced errors in estimating perfusion pressure of the isolated rat kidney

1982 ◽  
Vol 22 (6) ◽  
pp. 693-696 ◽  
Author(s):  
Rodger Loutzenhiser ◽  
Charles Horton ◽  
Murray Epstein
Keyword(s):  
Perfusion Pressure ◽  
Rat Kidney ◽  
Isolated Rat Kidney ◽  
Isolated Rat

Characterization of Ascorbic Acid Uptake by Isolated Rat Kidney Cells

1991 ◽  
Vol 121 (1) ◽  
pp. 57-64 ◽  
Author(s):  
Delores M. Bowers-Komro ◽  
Donald B. McCormick
Keyword(s):  
Ascorbic Acid ◽  
Rat Kidney ◽  
Acid Uptake ◽  
Kidney Cells ◽  
Isolated Rat Kidney ◽  
Isolated Rat

Toxicity of depleted uranium on isolated rat kidney mitochondria

2012 ◽  
Vol 1820 (12) ◽  
pp. 1940-1950 ◽  
Author(s):  
Fatemeh Shaki ◽  
Mir-Jamal Hosseini ◽  
Mahmoud Ghazi-Khansari ◽  
Jalal Pourahmad
Keyword(s):  
Rat Kidney ◽  
Depleted Uranium ◽  
Kidney Mitochondria ◽  
Isolated Rat Kidney ◽  
Isolated Rat
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