Short-Term Changes in Urinary Growth Hormone Excretion and Lower Leg Length in Healthy Children

1997 ◽  
Vol 48 (2) ◽  
pp. 72-75 ◽  
Author(s):  
S.F. Ahmed ◽  
S.I. Barnes ◽  
W.H.B. Wallace ◽  
C.J.H. Kelnar
Keyword(s):  
Growth Hormone ◽  
Lower Leg ◽  
Healthy Children ◽  
Leg Length ◽  
Short Term ◽  
Hormone Excretion

Short-term Changes in Lower Leg Length in Children Treated for Acute Lymphoblastic Leukaemia

1999 ◽  
Vol 12 (1) ◽  
Author(s):  
S.F. Ahmed ◽  
W.H.B. Wallace ◽  
P.M. Crofton ◽  
B. Wardhaugh ◽  
R. Magowan ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukaemia ◽  
Lymphoblastic Leukaemia ◽  
Lower Leg ◽  
Leg Length ◽  
Short Term

Urinary Growth Hormone Excretion in 657 Healthy Children and Adults: Normal Values, Inter- and Intraindividual Variations

1991 ◽  
Vol 36 (5-6) ◽  
pp. 174-182 ◽  
Author(s):  
Katharina Main ◽  
Malou Philips ◽  
Merete Jørgensen° ◽  
Niels Erik Skakkebœk
Keyword(s):  
Growth Hormone ◽  
Normal Values ◽  
Healthy Children ◽  
Hormone Excretion

The relationship between short-term changes in weight and lower leg length in children and young adults

1996 ◽  
Vol 23 (2) ◽  
pp. 159-162 ◽  
Author(s):  
S.F. Ahmed ◽  
B.W. Wardhaugh ◽  
J. Duff ◽  
W.H.B. Wallace ◽  
C.J.H. Kelnar
Keyword(s):  
Young Adults ◽  
Lower Leg ◽  
Leg Length ◽  
Short Term ◽  
Children And Young Adults ◽  
The Relationship

The Effect of Short Term Treatment With Growth Hormone and Ethinyl Estradiol on Lower Leg Growth Rate in Girls With Turner's Syndrome

1988 ◽  
Vol 67 (3) ◽  
pp. 515-518 ◽  
Author(s):  
JUDITH LEVINE ROSS ◽  
FERNANDO CASSORLA ◽  
GARY CARPENTER ◽  
LAUREN M. LONG ◽  
MARILYN S. ROYSTER ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Growth Rate ◽  
Ethinyl Estradiol ◽  
Lower Leg ◽  
Term Treatment ◽  
Turner's Syndrome ◽  
Turner’S Syndrome ◽  
Short Term ◽  
Short Term Treatment

No correlation between short term weight gain and lower leg length gain in healthy German children

2020 ◽  
Vol 77 (5) ◽  
pp. 399-403
Author(s):  
Arusa Maqsood ◽  
Daniel J. Naumenko ◽  
Michael Hermanussen ◽  
Christiane Scheffler ◽  
Detlef Groth
Keyword(s):  
Weight Gain ◽  
Lower Leg ◽  
Leg Length ◽  
Short Term ◽  
German Children ◽  
Length Gain

Different short-term effect of protein and carbohydrate intake on TSH, growth hormone (GH), insulin, C-peptide, and glucagon in humans

1990 ◽  
Vol 50 (7) ◽  
pp. 801-805 ◽  
Author(s):  
L. E. Matzen ◽  
B. B. Andersen ◽  
B. G. Jensen ◽  
H. J. Gjessing ◽  
S. H. Sindrup ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Term Effect ◽  
Carbohydrate Intake ◽  
Short Term ◽  
C Peptide ◽  
Short Term Effect

scholarly journals Differential Diagnosis of the Short IGF-I-Deficient Child with Apparently Normal Growth Hormone Secretion

2021 ◽  
pp. 1-24
Author(s):  
Jan M. Wit ◽  
Sjoerd D. Joustra ◽  
Monique Losekoot ◽  
Hermine A. van Duyvenvoorde ◽  
Christiaan de Bruin
Keyword(s):  
Growth Hormone ◽  
Differential Diagnosis ◽  
Growth Hormone Secretion ◽  
Normal Growth ◽  
Stimulation Test ◽  
Healthy Children ◽  
Genetic Causes ◽  
Gh Secretion ◽  
Igf I

The current differential diagnosis for a short child with low insulin-like growth factor I (IGF-I) and a normal growth hormone (GH) peak in a GH stimulation test (GHST), after exclusion of acquired causes, includes the following disorders: (1) a decreased spontaneous GH secretion in contrast to a normal stimulated GH peak (“GH neurosecretory dysfunction,” GHND) and (2) genetic conditions with a normal GH sensitivity (e.g., pathogenic variants of <i>GH1</i> or <i>GHSR</i>) and (3) GH insensitivity (GHI). We present a critical appraisal of the concept of GHND and the role of 12- or 24-h GH profiles in the selection of children for GH treatment. The mean 24-h GH concentration in healthy children overlaps with that in those with GH deficiency, indicating that the previously proposed cutoff limit (3.0–3.2 μg/L) is too high. The main advantage of performing a GH profile is that it prevents about 20% of false-positive test results of the GHST, while it also detects a low spontaneous GH secretion in children who would be considered GH sufficient based on a stimulation test. However, due to a considerable burden for patients and the health budget, GH profiles are only used in few centres. Regarding genetic causes, there is good evidence of the existence of Kowarski syndrome (due to <i>GH1</i> variants) but less on the role of <i>GHSR</i> variants. Several genetic causes of (partial) GHI are known (<i>GHR</i>, <i>STAT5B</i>, <i>STAT3</i>, <i>IGF1</i>, <i>IGFALS</i> defects, and Noonan and 3M syndromes), some responding positively to GH therapy. In the final section, we speculate on hypothetical causes.

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