A Comparative Study on the Effect of Atenolol and Labetalol on Exercise Capacity and Lipid Serum Levels in Essential Hypertension

Nephron ◽  
1987 ◽  
Vol 47 (1) ◽  
pp. 135-137 ◽  
Author(s):  
O. Schamaun ◽  
A. Westheim ◽  
E.K. Qvigstad ◽  
P. Teisberg
Keyword(s):  
Essential Hypertension ◽  
Comparative Study ◽  
Exercise Capacity ◽  
Serum Levels

scholarly journals A comparative study of salivary and serum calcium and alkaline phosphatase in patients with osteoporosis

2019 ◽  
Vol 7 (6) ◽  
pp. 2412
Author(s):  
Bijender Kumar Bairwa ◽  
Mamta Sagar ◽  
R. C. Gupta ◽  
Madhuri Gupta
Keyword(s):  
Alkaline Phosphatase ◽  
Comparative Study ◽  
Serum Calcium ◽  
Calcium Level ◽  
Serum Levels ◽  
Strong Positive Correlation ◽  
Medical Sciences ◽  
Easy Method ◽  
Positive Correlation ◽  
Non Invasive

Background: This study was undertaken to investigate the changes in salivary and serum calcium and alkaline phosphatase in osteoporosis patients. The objective was to compare the change in serum levels with those in saliva.Methods: The study was conducted in the department of biochemistry, National Institute of Medical Sciences and Hospital, Shobha Nagar, Jaipur, Rajasthan, India. Subjects were selected from department of orthopedics, National Institute of Medical Sciences and Hospital, Shobha Nagar, Jaipur, Rajasthan, India. At the same time one hundred adult osteoporosis patients confirmed by DEXA were taken. Calcium and alkaline phosphatase were measured in serum and saliva of each patient. The data obtained was statistically analyzed.Results: Serum calcium has strong positive correlation with salivary calcium (r=0.726) while serum ALP and salivary ALP had weak positive correlation (r =0.453).Conclusions: Saliva can be used to measure calcium level instead of serum as it is non-invasive, quick and easy method.

scholarly journals Increased Serum Levels of Asymmetric Dimethylarginine and Symmetric Dimethylarginine and Decreased Levels of Arginine in Sudanese Patients with Essential Hypertension

2020 ◽  
Vol 45 (5) ◽  
pp. 727-736
Author(s):  
Sahar Gamil ◽  
Jeanette Erdmann ◽  
Edzard Schwedhelm ◽  
Khalid Hussein Bakheit ◽  
Ihab B.B. Abdalrahman ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Essential Hypertension ◽  
Amino Acid ◽  
Asymmetric Dimethylarginine ◽  
Multivariate Logistic Regression Analysis ◽  
Serum Levels ◽  
Control Group ◽  
Multivariate Logistic Regression ◽  
Symmetric Dimethylarginine

Introduction: Essential hypertension (EH) is a disease caused by various environmental and genetic factors. Nitric oxide (NO) is important for the functional integrity of the endothelium. It is produced in endothelial cells by endothelial NO synthase (eNOS) that mediates the conversion of the amino acid arginine into NO and citrulline. Asymmetric dimethylarginine (ADMA) acts as an inhibitor of eNOS. In contrast, symmetric dimethylarginine (SDMA) has no direct effect on eNOS but plays an important role competing with arginine for transport across the amino acid transporter. ADMA and SDMA have been found to play a central role in the development of cardiovascular diseases. Serum ADMA levels may serve as a future diagnostic marker and a target of therapy in hypertensive patients in the Sudanese population. This study aimed to investigate the relation between serum arginine, ADMA, and SDMA levels with EH in the Sudanese population. Methods: Patients (n = 260) with established hypertension and controls (n = 144) with normal blood pressure were included in this case-control study. Serum blood samples were analyzed for arginine, ADMA, and SDMA, using high-performance liquid chromatography-tandem mass spectrometry. Other laboratory data were measured using routine methods. Mann-Whitney’s U test and χ2 tests were used for continuous and categorical data, respectively. A multivariate logistic regression analysis was conducted to investigate the independent effect of multiple variables on the development of hypertension. Results: Serum arginine levels were significantly lower in the patient group than in the control group (p < 0.001). ADMA and SDMA levels were significantly higher in the patient group than the control group (p < 0.001, p = 0.001, respectively). Multivariate logistic regression analysis showed that only older age, being a male, and arginine levels are independent factors controlling the development of hypertension (p < 0.001, p < 0.001, and p = 0.046, respectively). ADMA and SDMA levels were not independent factors for the development of hypertension. Conclusions: This study demonstrated increased serum levels of ADMA and SDMA and decreased arginine levels in Sudanese patients with EH. Lowering serum ADMA levels or increasing the arginine levels might be a novel therapeutic target in these individuals.

scholarly journals Serum levels of the Th1 chemoattractant interferon-gamma-inducible protein (IP) 10 are elevated in patients with essential hypertension

2011 ◽  
Vol 34 (4) ◽  
pp. 484-488 ◽  
Author(s):  
Christian Stumpf ◽  
Christoph Auer ◽  
Atilla Yilmaz ◽  
Piotr Lewczuk ◽  
Lutz Klinghammer ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Interferon Gamma ◽  
Serum Levels ◽  
Inducible Protein

Evaluation of Dermatophagoides pteronyssinus (Trouessart) and D. farinae Hughes (Acari: Pyroglyphidae) sensitivity in patients with allergic rhinitis: a comparative study

2018 ◽  
Vol 23 (2) ◽  
pp. 206
Author(s):  
Erhan ZEYTUN ◽  
Salih DOĞAN ◽  
Edhem Ünver ◽  
Fatih ÖZÇÜÇEK
Keyword(s):  
Allergic Rhinitis ◽  
Comparative Study ◽  
Clinical Assessment ◽  
Serum Levels ◽  
Specific Ige ◽  
Dermatophagoides Pteronyssinus ◽  
Total Ige ◽  
Serologic Tests ◽  
Stereo Microscope ◽  
Skin Prick Tests

This study was conducted to determine the sensitivity to Dermatophagoides pteronyssinus (Trouessart) and D. farinae Hughes with skin prick tests (SPT) and serologic tests in patients with allergic rhinitis (AR), and to specifically search for those mites in homes of patients. A total of 51 participants, (23 patients and 28 controls) were utilized. Skin-prick tests with D. pteronyssinus and D. farinae allergens were performed on all participants, and serum levels of allergen-specific lgE and total IgE were also measured. Dust samples were collected from homes of all participants and examined under a stereo microscope. 977 D. pteronyssinus (mean 44.4/g) and 24 D. farinae (mean 4.0/g) were isolated from the homes of patients, whereas 35 D. pteronyssinus (mean 4.4/g), and four D. farinae (mean 2.0/g) were isolated from the homes of the controls. Patients with D. pteronyssinus in their homes had 95.5% sensitivity to the species according to SPT and 27.3 according to IgE. Patients with D. farinae in their homes had 83.3% sensitivity to the species according to SPT, and 50% according to IgE. Dermatophagoides pteronyssinus sensitivity in the controls was detected as 12.5% according to SPT; however, D. farinae sensitivity was not detected according to both SPT and mite-specific IgE. Differences between patients and controls utilizing SPT results was statistically significant, but not when using mite-specific IgE results. As a result, it was determined that patients with AR in Erzincan province were sensitized to D. pteronyssinus and D. farinae, and that their homes contained those species. It may be helpful to consider these findings in clinical assessment of patients with AR, and also in treatment utilizing immunotherapy techniques.

A Comparative Study Between 100mg Atenolol and 20mg Pindolol Slow-Release in Essential Hypertension

Drugs ◽  
1983 ◽  
Vol 25 (Supplement 2) ◽  
pp. 37-41 ◽  
Author(s):  
P. Greminger ◽  
H. Vetter ◽  
H.J. Boerlin ◽  
J. Havelka ◽  
P. Baumgart ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Comparative Study ◽  
Slow Release

A Comparative Study of Serum Levels of the Anti inflammatory Cytokines IL-35 in Allergic Asthma and H. pylori Infected Patients

2019 ◽  
Vol 10 (6) ◽  
pp. 824
Author(s):  
Abbas Fadhil Hato ◽  
Alia Essam Mahmood Alubadi ◽  
Suad Almas Brakhas ◽  
Ali Haider Abdoul-Hadi Alsakini
Keyword(s):  
Comparative Study ◽  
Allergic Asthma ◽  
Inflammatory Cytokines ◽  
Serum Levels ◽  
Anti Inflammatory ◽  
H Pylori
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