scholarly journals Serum levels of the Th1 chemoattractant interferon-gamma-inducible protein (IP) 10 are elevated in patients with essential hypertension

2011 ◽  
Vol 34 (4) ◽  
pp. 484-488 ◽  
Author(s):  
Christian Stumpf ◽  
Christoph Auer ◽  
Atilla Yilmaz ◽  
Piotr Lewczuk ◽  
Lutz Klinghammer ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Interferon Gamma ◽  
Serum Levels ◽  
Inducible Protein

Etanercept treatment reduces the serum levels of interleukin-15 and interferon-gamma inducible protein-10 in patients with rheumatoid arthritis

2010 ◽  
Vol 30 (6) ◽  
pp. 725-730 ◽  
Author(s):  
Tetsuya Ichikawa ◽  
Yasunori Kageyama ◽  
Hayato Kobayashi ◽  
Norihiko Kato ◽  
Kunio Tsujimura ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Interferon Gamma ◽  
Serum Levels ◽  
Etanercept Treatment ◽  
Interleukin 15 ◽  
Inducible Protein

Pretreatment serum levels of interferon-gamma-inducible protein-10 are associated with virologic response to telaprevir-based therapy

Cytokine ◽  
2016 ◽  
Vol 88 ◽  
pp. 29-36 ◽  
Author(s):  
Yoko Yamagiwa ◽  
Mai Asano ◽  
Youhei Kawasaki ◽  
Masaaki Korenaga ◽  
Kazumoto Murata ◽  
...  
Keyword(s):  
Interferon Gamma ◽  
Serum Levels ◽  
Virologic Response ◽  
Inducible Protein ◽  
Pretreatment Serum

Serum levels of interferon-gamma-inducible protein 10 and response to peginterferon therapy in HBeAg-positive chronic hepatitis B

2013 ◽  
Vol 58 (5) ◽  
pp. 898-903 ◽  
Author(s):  
Milan J. Sonneveld ◽  
Pauline Arends ◽  
Andre Boonstra ◽  
Bettina E. Hansen ◽  
Harry L.A. Janssen
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Interferon Gamma ◽  
Serum Levels ◽  
Positive Chronic Hepatitis ◽  
Inducible Protein

scholarly journals Enterovirus 71 infection increases expression of interferon-gamma-inducible protein 10 which protects mice by reducing viral burden in multiple tissues

2013 ◽  
Vol 94 (5) ◽  
pp. 1019-1027 ◽  
Author(s):  
Fang-Hsiu Shen ◽  
Chia-Chun Tsai ◽  
Li-Chiu Wang ◽  
Kung-Chao Chang ◽  
Yuk-Ying Tung ◽  
...  
Keyword(s):  
T Cells ◽  
Interferon Gamma ◽  
Cd8 T Cells ◽  
Enterovirus 71 ◽  
Gamma Interferon ◽  
Ev71 Infection ◽  
Asia Pacific ◽  
Virus Clearance ◽  
Viral Burden ◽  
Inducible Protein

Enterovirus 71 (EV71) infection has induced fatal encephalitis in thousands of young children in the Asia–Pacific region over the last decade. EV71 infection continues to cause serious problems in areas with outbreaks, because vaccines and antiviral therapies are not available. Lymphocytes are present in the brains of infected patients and mice, and they protect mice from infection by decreasing the viral burden. The chemokines responsible for recruiting lymphocytes to infected organs are yet to be identified. Among the lymphocyte chemokines detected, high levels of interferon-gamma-inducible protein-10 (IP-10) are found in the plasma and cerebral spinal fluid of patients with brainstem encephalitis as compared with the levels of a monokine induced by gamma interferon (Mig). Using a murine model to investigate the induction of IP-10 by EV71 infection, we observed that EV71 infection significantly enhanced IP-10 protein expression in the serum and brain, with kinetics similar to viral titres in the blood and brain. Brain neurons of infected mice expressed IP-10. Using wild-type mice and IP-10 gene knockout mice to investigate the role of IP-10 in EV71 infection, we found that IP-10 deficiency significantly reduced levels of Mig in serum, and levels of gamma interferon and the number of CD8 T cells in the mouse brain. Absence of IP-10 significantly increased the mortality of infected mice by 45 %, with slow virus clearance in several vital tissues. Our observations are consistent with a model where EV71 infection boosts IP-10 expression to increase gamma interferon and Mig levels, infiltration of CD8 T cells, virus clearance in tissues and the survival of mice.

A Comparative Study on the Effect of Atenolol and Labetalol on Exercise Capacity and Lipid Serum Levels in Essential Hypertension

Nephron ◽  
1987 ◽  
Vol 47 (1) ◽  
pp. 135-137 ◽  
Author(s):  
O. Schamaun ◽  
A. Westheim ◽  
E.K. Qvigstad ◽  
P. Teisberg
Keyword(s):  
Essential Hypertension ◽  
Comparative Study ◽  
Exercise Capacity ◽  
Serum Levels

Murine interferon-gamma inducible protein-10 (IP-10) secreted by Lactococcus lactis chemo-attracts human CD3+ lymphocytes

2009 ◽  
Vol 31 (11) ◽  
pp. 1795-1800 ◽  
Author(s):  
Julio Villatoro-Hernandez ◽  
Alma Yolanda Arce-Mendoza ◽  
Adrian G. Rosas-Taraco ◽  
Sandra Cecilia Esparza-González ◽  
Santos Guzmán-López ◽  
...  
Keyword(s):  
Lactococcus Lactis ◽  
Interferon Gamma ◽  
Inducible Protein
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