Possible Role of Vasoactive Intestinal Polypeptide on Prolactin Release during Suckling in Lactating Women

1987 ◽  
Vol 27 (4) ◽  
pp. 211-215 ◽  
Author(s):  
Ermanno Rolandi ◽  
Nicola Ragni ◽  
Roberto Fanceschini ◽  
Pier Luigi Venturing ◽  
Valeria Messina ◽  
...  
Keyword(s):  
Vasoactive Intestinal Polypeptide ◽  
Prolactin Release ◽  
Lactating Women ◽  
Intestinal Polypeptide

scholarly journals Development-Dependent Plasticity in Vasoactive Intestinal Polypeptide Neurons in the Infralimbic Cortex

2021 ◽  
Vol 2 (1) ◽  
Author(s):  
Stuart A Collins ◽  
Ipe Ninan
Keyword(s):  
Sex Differences ◽  
Anxiety Disorders ◽  
Vasoactive Intestinal Polypeptide ◽  
Cortical Plasticity ◽  
Male Mice ◽  
Infralimbic Cortex ◽  
Membrane Excitability ◽  
Gabaergic Transmission ◽  
Intestinal Polypeptide

Abstract The onset of several neuropsychiatric disorders including anxiety disorders coincides with adolescence. Consistently, threat extinction, which plays a key role in the regulation of anxiety-related behaviors, is diminished during adolescence. Furthermore, this attenuated threat extinction during adolescence is associated with an altered synaptic plasticity in the infralimbic medial prefrontal cortex (IL-mPFC), a brain region critical for threat extinction. However, the mechanism underlying the altered plasticity in the IL-mPFC during adolescence is unclear. Given the purported role of vasoactive intestinal polypeptide expressing interneurons (VIPINs) in disinhibition and hence their potential to affect cortical plasticity, we examined whether VIPINs exhibit an adolescence-specific plasticity in the IL-mPFC. We observed an increase in GABAergic transmission and a decrease in excitability in VIPINs during adolescence. Male mice show a significantly higher VIPIN-pyramidal neuron GABAergic transmission compared with female mice. The observed increase in GABAergic transmission and a decrease in membrane excitability in VIPINs during adolescence could play a role in the altered plasticity in the adolescent IL-mPFC. Furthermore, the suppression of VIPIN-mediated GABAergic transmission in females might be relevant to sex differences in anxiety disorders.

The Role of Vasoactive Intestinal Polypeptide as a Neurotransmitter in Canine Penile Erection: A Combined in Vivo and Immunohistochemical Study

1987 ◽  
Vol 138 (4 Part 1) ◽  
pp. 871-877 ◽  
Author(s):  
Klaus-Peter Juenemann ◽  
Tom F. Lue ◽  
Jian-An Luo ◽  
Sami A. Jadallah ◽  
Lora L. Nunes ◽  
...  
Keyword(s):  
Vasoactive Intestinal Polypeptide ◽  
Penile Erection ◽  
Immunohistochemical Study ◽  
Intestinal Polypeptide

Reduced vasoactive intestinal polypeptide immunoreactivity in the pituitaries of hormone-deficient mutant mice

1988 ◽  
Vol 118 (2) ◽  
pp. 179-NP ◽  
Author(s):  
T. Noguchi ◽  
T. Sugisaki ◽  
T. Kanamatsu ◽  
I. Satoh ◽  
N. Nishikawa
Keyword(s):  
Vasoactive Intestinal Polypeptide ◽  
Anterior Pituitary ◽  
Mutant Mice ◽  
Target Cells ◽  
Retrograde Flow ◽  
Deficient Mutant ◽  
High Concentration ◽  
Prolactin Release ◽  
Intestinal Polypeptide

ABSTRACT The prolactin-producing cells of the bovine anterior pituitary were found to contain a vasoactive intestinal polypeptide (VIP) immunoreactive substance, thus suggesting a role for VIP in the regulation of prolactin release. The pituitaries of the dw and lit strains of mutant mice, congenitally deficient in prolactin-producing cells, and hyt mice, which were found to have reduced numbers of prolactin-producing cells, showed a markedly reduced VIP immunoreactivity. Hypothalamic VIP immunoreactivity, however, was found to be unchanged in the three strains of mutant mice, indicating that the high concentration of VIP in the hypothalamus does not derive from the adenohypophysis through retrograde flow. The deficiency in the mutant mice seems to be due to the lack of prolactin target cells in the pituitary. J. Endocr. (1988) 118, 179–185

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