Further Studies on the Relationship of Adrenal and Gonadal Steroids in Pubertal Development in Female Rats

1979 ◽  
Vol 10 (2-3) ◽  
pp. 130-142 ◽  
Author(s):  
J.R. Ducharme ◽  
A.M. Morera ◽  
P. Laurin ◽  
R. Collu ◽  
L. Audi ◽  
...  
Keyword(s):  
Pubertal Development ◽  
Gonadal Steroids ◽  
Female Rats ◽  
Relationship Of ◽  
The Relationship

Sex Differences in Body-Weight Change following Gonadectomy of Rats

1968 ◽  
Vol 22 (2) ◽  
pp. 547-554 ◽  
Author(s):  
Jan W. Kakolewski ◽  
Verne C. Cox ◽  
Elliot S. Valenstein
Keyword(s):  
Body Weight ◽  
Sex Differences ◽  
Female Rats ◽  
Body Weight Change ◽  
Review Of The Literature ◽  
Male And Female ◽  
Male And Female Rats ◽  
Relationship Of ◽  
The Relationship ◽  
Hypothalamic Damage

Data are presented to demonstrate that the effects of gonadectomy on body weight and food consumption differ in male and female rats. The findings are related to the authors' report of sex differences in the effects of ventromedial hypothalamic damage. A review of the literature on the relationship of the gonads to body weight in different species is presented.

MESENTERIC NEUTRAL FAT IN OBESE RATS

1958 ◽  
Vol 36 (1) ◽  
pp. 913-918
Author(s):  
Eldon M. Boyd ◽  
Eleanor M. Crandell
Keyword(s):  
Free Cholesterol ◽  
Dry Weight ◽  
Female Rats ◽  
Albino Rats ◽  
Fat Depots ◽  
Mesenteric Fat ◽  
Obese Rats ◽  
Physiologic Function ◽  
Relationship Of ◽  
The Relationship

The relationship of increasing obesity to storage of neutral fat in the mesentery was investigated in 48 albino rats. Calculated as grams per 100 g nonlipid dry weight, levels of mesenteric neutral fat were positively correlated with levels of mesenteric free cholesterol, phospholipid, and water, the correlation coefficient for water being higher in male than in female rats. These results suggest that storage of neutral fat is an active physiologic function of mesentery. On the other hand, the relative amount of body neutral fat which is stored in the mesentery became less as the animals became more obese. This indicates that in obese rats, some tissue other than mesentery is storing neutral fat at a rate greater than occurs in the mesenteric fat depots.

Pancreatic Hepatocytes Associated with Chronic 2,6-Dichloro-p-Phenylenediamine Administration in Fischer 344 Rats

1989 ◽  
Vol 17 (1_part_1) ◽  
pp. 1-6 ◽  
Author(s):  
Margarita M. McDonald ◽  
Gary A. Boorman
Keyword(s):  
Light Microscopy ◽  
Pancreatic Tissue ◽  
Female Rats ◽  
Fischer 344 Rats ◽  
Fischer 344 ◽  
Relationship Of ◽  
The Relationship ◽  
Pancreatic Hepatocytes

Pancreatic tissue (original and recut sections) from Fischer 344 rats fed 2,6-dichloro-p-phenylenediamine in a chronic (2-year) carcinogenesis bioassay was evaluated for presence of pancreatic hepatocytes (PH) by light microscopy. PH were found in dose groups as follows: males–0 ppm (controls)–0/50 (0%), 1,000 ppm–4/50 (8%), 2,000 ppm–9/50 (18%); females-0 ppm (controls)–1/50 (2%), 2,000 ppm–15/50 (30%), 6,000 ppm–15/49 (31%). This represented a significant dose-related increased incidence of PH in 2,000-ppm males, and 2,000- and 6,000-ppm females. A statistically significant increase ( p < 0.01) in pancreatic acinar atrophy and fibrosis was also seen in treated female rats, but the relationship of these lesions to the PH is unclear.

MESENTERIC NEUTRAL FAT IN OBESE RATS

1958 ◽  
Vol 36 (9) ◽  
pp. 913-918 ◽  
Author(s):  
Eldon M. Boyd ◽  
Eleanor M. Crandell
Keyword(s):  
Free Cholesterol ◽  
Dry Weight ◽  
Female Rats ◽  
Albino Rats ◽  
Fat Depots ◽  
Mesenteric Fat ◽  
Obese Rats ◽  
Physiologic Function ◽  
Relationship Of ◽  
The Relationship

The relationship of increasing obesity to storage of neutral fat in the mesentery was investigated in 48 albino rats. Calculated as grams per 100 g nonlipid dry weight, levels of mesenteric neutral fat were positively correlated with levels of mesenteric free cholesterol, phospholipid, and water, the correlation coefficient for water being higher in male than in female rats. These results suggest that storage of neutral fat is an active physiologic function of mesentery. On the other hand, the relative amount of body neutral fat which is stored in the mesentery became less as the animals became more obese. This indicates that in obese rats, some tissue other than mesentery is storing neutral fat at a rate greater than occurs in the mesenteric fat depots.

Blood Oxygen Capacity of Albino Rats

1956 ◽  
Vol 188 (1) ◽  
pp. 118-120 ◽  
Author(s):  
Jack D. Burke
Keyword(s):  
Body Weight ◽  
Rattus Norvegicus ◽  
Female Rats ◽  
Albino Rats ◽  
Blood Oxygen ◽  
Oxygen Capacity ◽  
Relationship Of ◽  
The Relationship ◽  
Weight Groups

The oxygen capacity of the blood of 64 albino Rattus norvegicus (Sherman strain) was determined by the microgasometric syringe method. Data were obtained showing the relationship of blood oxygen capacity to weight and sex of the animals. It was found that blood oxygen capacity in volumes per cent increased as the weight of the rats increased. Statistically, there was no difference in the blood values in either male or female rats as analyzed in different weight groups and ranges. Also, the oxygen capacity of the blood per unit of body weight decreased as the weight of the rats increased.

THE RELATIONSHIP OF SERUM PHOSPHATASES TO SEX HORMONES

1949 ◽  
Vol 27e (3) ◽  
pp. 202-209 ◽  
Author(s):  
Jules Tuba ◽  
Donald B. Baker ◽  
Max M. Cantor
Keyword(s):  
Serum Alkaline Phosphatase ◽  
Inorganic Phosphorus ◽  
Female Rats ◽  
Male Rats ◽  
Normal Male ◽  
Normal Female ◽  
Hormone Injection ◽  
Relationship Of ◽  
The Relationship ◽  
Phosphorus Levels

Castration produces a fall in serum inorganic phosphorus values in adult male rats but not in adult female rats. The alterations of phosphorus levels that occur following castration in male rats and after the injection of some hormones into normal and castrated rats of both sexes may be accounted for by corresponding alterations in metabolic requirements. Neither castration nor hormone injection produces any significant change in serum acid phosphatase activity in male or in female rats. A fall of about 30% to levels approaching values for normal female rats is found in serum alkaline phosphatase of castrated male rats in about eight weeks. There is no change in the enzyme values in castrated females. In those instances where injections of a sex hormone into castrated or normal rats produce alterations in alkaline serum phosphatase values such changes may be accounted for on the basis of altered food intake. The sole exception to this finding is the very marked decrease in the activity of the enzyme produced by progesterone after oestrogen in normal male rats.

scholarly journals Sexual maturation in girls: association with physical activity and sedentary behaviour

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
V Desnouck ◽  
C Pedroni ◽  
M Dujeu ◽  
N Moreau ◽  
T Lebacq ◽  
...  
Keyword(s):  
Physical Activity ◽  
Sedentary Behaviour ◽  
Sexual Maturation ◽  
Pubertal Development ◽  
Negative Consequences ◽  
Cross Sectional ◽  
School Aged Children ◽  
French Speaking ◽  
Relationship Of ◽  
The Relationship

Abstract Introduction During adolescence, physical activity tends to decline, especially among girls. Adolescent inactivity is due in part to biological factors, among which pubertal development may play a role. Our aim was to study in girls, the relationship of sexual maturation based on menarche with physical activity and sedentary behaviour. Methods Analyses were based on a two-stage random sample of 3,911 10-15-year-old girls included in the 2018 cross-sectional Health Behaviour in School-aged Children survey carried out in French-speaking schools. Menarche, sufficient levels of physical activity (PA) (global PA: at least 60 min. of moderate- to vigorous-intensity PA daily, and vigorous PA: at least 3 times/week), sedentary week time based on all-screen use duration (SWT; categories based on tertiles), and sociodemographic characteristics were self-reported. Multilevel multiple binary (for PA) and multinomial (for SWT) logistic regressions were performed, stratified by age group (≤12.5 years vs. &gt;12.5 years). Results Twenty percent of girls aged ≤ 12.5 years and 85.0% of girls aged &gt; 12.5 years have had their first period. Within the group aged ≤12.5, post-menarcheal girls were more likely to spend long SWT (≥8h/day) than pre-menarcheal girls (vs. short SWT (&lt;4h/day): aRRR= 1.74 [1.27-2.37]; NS for moderate SWT (4-7h/day)). Within those aged &gt;12.5, post-menarcheal girls were less likely to engage in sufficient vigorous PA (aOR=0.76 [0.59-0.98]) than pre-menarcheal girls. Moreover, they were more likely to spend moderate (aRRR=1.70 [1.19-2.42]) and long SWT (aRRR=2.74 [1.94-3.88]) than pre-menarcheal girls of same ages. Additional adjustments for age modified the strength of associations. Conclusions Our results suggest that during adolescence, the physiological changes induced by sexual maturation may contribute to the decline in physical activity (in &gt; 12.5 years), and in the increase in sedentary behaviour in girls. Potential confounding by age will be explored further. Key messages Development of strategies aimed at improving physical activity among adolescent girls should take into account, among other aspects, pubertal development. Specific interventions, targeting pubescent girls, should also be developed to reduce screen time in order to prevent its potential negative consequences.

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