scholarly journals The Future of Breast Cancer Diagnostics

Breast Care ◽  
2008 ◽  
Vol 3 (6) ◽  
pp. 384-387 ◽  
Author(s):  
Felix Diekmann ◽  
Susanne Diekmann
Keyword(s):  
Breast Cancer ◽  
Cancer Diagnostics ◽  
Breast Cancer Diagnostics ◽  
The Future

Micropattern Effect on Breast Cancer Cells Behavior on Isotropically Etched Silicon Microenvironments

2010 ◽  
Author(s):  
Mehdi Nikkhah ◽  
Jeannine S. Strobl ◽  
Bhanu Peddi ◽  
Adedamola Omotosho ◽  
Masoud Agah
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Three Dimensional ◽  
Cancer Diagnostics ◽  
Breast Cancer Diagnostics ◽  
Wide Range ◽  
Etched Silicon ◽  
Directed Motility ◽  
Etched Surface ◽  
Silicon Based

In this paper we are investigating three dimensional (3-D) silicon-based microenvironments as potential platforms for breast cancer diagnostics. We have developed isotropically etched microstructures with a wide range of geometrical patterns for this purpose. Our results indicate that with the etched surface ratio of ∼65%, it is possible to capture 80–90% of the cancer cells within each silicon chip. After treatment of the cells with mitomycin C (to block the cell growth) more number of the cells are trapped inside the etched features for longer cultures times (72 h) suggesting that there is a directed motility and attraction of the cells toward the etched cavities and by optimally designing the etched features, the proposed platforms can be potentially used for diagnostics purposes.

Nonlinear Microscopy as a Tool of Express Biopsy in Breast Cancer Diagnostics

2018 ◽  
Author(s):  
E.A. Sergeeva ◽  
V.V. Dudenkova ◽  
S.S. Kuznetsov ◽  
M.Yu. Kirillin ◽  
M.V. Pavlov ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Diagnostics ◽  
Nonlinear Microscopy ◽  
Breast Cancer Diagnostics

Advanced antifouling zwitterionic layer based impedimetric HER2 biosensing in human serum: Glycoprofiling as a novel approach for breast cancer diagnostics

2018 ◽  
Vol 272 ◽  
pp. 626-633 ◽  
Author(s):  
Erika Chocholova ◽  
Tomas Bertok ◽  
Lenka Lorencova ◽  
Alena Holazova ◽  
Pavol Farkas ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Human Serum ◽  
Cancer Diagnostics ◽  
Breast Cancer Diagnostics ◽  
Novel Approach

Breast cancer diagnostics by Raman spectroscopy

2008 ◽  
Vol 141 (3) ◽  
pp. 145-148 ◽  
Author(s):  
B. Brożek-Płuska ◽  
I. Placek ◽  
K. Kurczewski ◽  
Z. Morawiec ◽  
M. Tazbir ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Raman Spectroscopy ◽  
Cancer Diagnostics ◽  
Breast Cancer Diagnostics

scholarly journals Molecular Profiling for Breast Cancer: A Comprehensive Review

2013 ◽  
Vol 5 ◽  
pp. BIC.S9455 ◽  
Author(s):  
Muaiad Kittaneh ◽  
Alberto J. Montero ◽  
Stefan Glück
Keyword(s):  
Breast Cancer ◽  
Early Stage ◽  
Recurrence Risk ◽  
Cancer Diagnostics ◽  
Breast Cancer Patients ◽  
Breast Cancer Diagnostics ◽  
Molecular Tests ◽  
Standard Clinical Practice ◽  
Medical Oncologists ◽  
Polymerase Chain

In recent years advances in molecular biology have launched disruptive innovations in breast cancer diagnostics and therapeutics. The advent of genomics has revolutionized our understanding of breast cancer as several different biologically and molecularly distinct diseases. This research has led to commercially available polymerase chain reaction (PCR) and microarray tests that have begun to fundamentally change the way medical oncologists quantify recurrence risk in early stage breast cancer patients. The Genomics era has altered the clinicopathologic paradigm of selecting patients for adjuvant cytotoxic chemotherapy. Sufficiently powered prospective studies are underway that may establish these molecular assays as elements of standard clinical practice in breast cancer treatment. In this article, we review the strengths and limitations of currently available breast cancer-specific molecular tests.

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