Amino Acid Tablet-Substituted Diets in the Management of Chronic Renal Failure

1974 ◽  
Vol 17 (3) ◽  
pp. 154-165 ◽  
Author(s):  
H.A. Lee ◽  
P.F. Down ◽  
E. Fowell ◽  
B.E.H. Hyne
1991 ◽  
Vol 40 (3) ◽  
pp. 539-543 ◽  
Author(s):  
Eldar Söreide ◽  
Björn Skeie ◽  
Olli Kirvelä ◽  
Robert Lynn ◽  
Nancy Ginsberg ◽  
...  

1993 ◽  
Vol 265 (2) ◽  
pp. E230-E235 ◽  
Author(s):  
D. Reaich ◽  
S. M. Channon ◽  
C. M. Scrimgeour ◽  
S. E. Daley ◽  
R. Wilkinson ◽  
...  

The effect of correction of acidosis in chronic renal failure (CRF) was determined from the kinetics of infused L-[1-13C]leucine. Nine CRF patients were studied before (acid) and after two 4-wk treatment periods of sodium bicarbonate (NaHCO3) and sodium chloride (NaCl) (pH: acid 7.31 +/- 0.01, NaHCO3 7.38 +/- 0.01, NaCl 7.30 +/- 0.01). Leucine appearance from body protein (PD), leucine disappearance into body protein (PS) and leucine oxidation (O) decreased significantly with correction of acidosis (PD: acid 122.4 +/- 6.1, NaHCO3 88.3 +/- 6.9, NaCl 116.2 +/- 9.1 mumol.kg-1.h-1, acid vs. NaHCO3 P < 0.01, NaHCO3 vs. NaCl P < 0.01, acid vs. NaCl NS; PS: acid 109.4 +/- 5.6, NaHCO3 79.0 +/- 6.3, NaCl 101.3 +/- 7.7 mumol.kg-1.h-1, acid vs. NaHCO3 P < 0.01, NaHCO3 vs. NaCl P < 0.01, acid vs. NaCl NS; O: acid 13.0 +/- 1.2, NaHCO3 9.2 +/- 0.9, NaCl 15.0 +/- 1.9 mumol.kg-1.h-1, acid vs. NaHCO3 P < 0.05, NaHCO3 vs. NaCl P < 0.01, acid vs. NaCl NS). There were no significant changes in plasma amino acid concentrations. These results confirm that correction of acidosis in chronic renal failure removes a potential catabolic factor.


Author(s):  
Giacomo Deferrari ◽  
Giacomo Garibotto ◽  
Cristina Robaudo ◽  
Stefano Saffioti ◽  
Ernesto Paoletti ◽  
...  

1987 ◽  
Vol 14 (5) ◽  
pp. 8-11
Author(s):  
J. Bergström ◽  
M. Ahlberg ◽  
A. Alvestrand ◽  
P. Fürst

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