Release of Free Fatty Acids from Adipose Tissue in vitro after Adrenalin in Relation to the Total Body Fat in Rats of Different Age and Different Physical Activity

1967 ◽  
Vol 9 (1) ◽  
pp. 43-55
Author(s):  
J. Pařízková ◽  
L. Stañková
Keyword(s):  
Physical Activity ◽  
Fatty Acids ◽  
Adipose Tissue ◽  
Free Fatty Acids ◽  
Body Fat ◽  
Total Body Fat ◽  
Total Body

scholarly journals Improved insulin sensitivity after gastric bypass correlates with decreased total body fat, but not with changes in free fatty acids

2013 ◽  
Vol 28 (5) ◽  
pp. 1489-1493 ◽  
Author(s):  
Alessandro Mor ◽  
Lawrence Tabone ◽  
Philip Omotosho ◽  
Alfonso Torquati
Keyword(s):  
Fatty Acids ◽  
Gastric Bypass ◽  
Insulin Sensitivity ◽  
Free Fatty Acids ◽  
Body Fat ◽  
Total Body Fat ◽  
Total Body

ON THE EFFECT OF THE THYROID ON THE METABOLISM OF FREE FATTY ACIDS AND CHOLESTEROL IN FASTING RATS

1966 ◽  
Vol 44 (3) ◽  
pp. 443-449
Author(s):  
V. Felt
Keyword(s):  
Fatty Acids ◽  
Adipose Tissue ◽  
Uric Acid ◽  
Oxygen Consumption ◽  
Free Fatty Acids ◽  
Heart Weight ◽  
Fasting Serum ◽  
Total Body ◽  
Total Body Oxygen

Fasting markedly influences the effect of l-thyroxine on the metabolism of free fatty acids (FFA) and cholesterol in rats. In fed rats thyroxine raises the FFA content of serum and of adipose tissue and increases the liberation of FFA from the latter; in some animals there also occurs an increase in serum cholesterol. These differences are absent in fasting animals. After 48 hours of fasting, serum FFA and FFA liberation from adipose tissue are higher in controls than in thyroxine-treated animals. Total body oxygen consumption remains increased in thyroxine-treated animals even after 48 hours of fasting. Data are given on changes in glycemia, serum uric acid, and heart weight. Phentolamine in vitro was without effect on the liberation of FFA from adipose tissue either in thyroxine-treated animals or in controls.

White adipose tissue sensory nerve denervation mimics lipectomy-induced compensatory increases in adiposity

2005 ◽  
Vol 289 (2) ◽  
pp. R514-R520 ◽  
Author(s):  
Haifei Shi ◽  
Timothy J. Bartness
Keyword(s):  
Adipose Tissue ◽  
Body Fat ◽  
White Adipose Tissue ◽  
Sensory Nerve ◽  
Sensory Innervation ◽  
Siberian Hamsters ◽  
Total Body Fat ◽  
Total Body ◽  
Lipid Stores ◽  
The Brain

The sensory innervation of white adipose tissue (WAT) is indicated by the labeling of sensory bipolar neurons in the dorsal root ganglion after retrograde dye placement into WAT. In addition, immunoreactivity (ir) for sensory-associated neuropeptides such as calcitonin gene-related peptide (CGRP) and substance P in WAT pads also supports the notion of WAT sensory innervation. The function of this sensory innervation is unknown but could involve conveying the degree of adiposity to the brain. In tests of total body fat regulation, partial surgical lipectomy triggers compensatory increases in the mass of nonexcised WAT, ultimately resulting in restoration of total body fat levels in Siberian hamsters and other animals. The signal that triggers this compensation is unknown but could involve disruption of WAT sensory innervation that accompanies lipectomy. Therefore, a local and selective sensory denervation was accomplished by microinjecting the sensory nerve neurotoxin capsaicin bilaterally into epididymal WAT (EWAT) of Siberian hamsters, whereas controls received vehicle injections. Additional hamsters had bilateral EWAT lipectomy (EWATx) or sham lipectomy. As seen previously, EWATx resulted in significantly increased retroperitoneal WAT (RWAT) and inguinal WAT (IWAT) masses. Capsaicin treatment significantly decreased CGRP- but not tyrosine hydroxylase-ir, attesting to the diminished and selective sensory innervation. Capsaicin-treated hamsters also had increased RWAT and, to a lesser degree, IWAT mass largely mimicking the WAT mass increases seen after lipectomy. Collectively, these data suggest the possibility that information related to peripheral lipid stores may be conveyed to the brain via the sensory innervation of WAT.

Effect of nicotine on the mobilization of free fatty acids from adipose tissue in vitro

1969 ◽  
Vol 25 (2) ◽  
pp. 128-128 ◽  
Author(s):  
A. Kershbaum ◽  
H. Osada ◽  
D. J. Pappajohn ◽  
S. Bellet
Keyword(s):  
Fatty Acids ◽  
Adipose Tissue ◽  
Free Fatty Acids ◽  
Adipose Tissue In Vitro

Innervation of mammalian white adipose tissue: implications for the regulation of total body fat

1998 ◽  
Vol 275 (5) ◽  
pp. R1399-R1411 ◽  
Author(s):  
Timothy J. Bartness ◽  
Maryam Bamshad
Keyword(s):  
Nervous System ◽  
Adipose Tissue ◽  
Body Fat ◽  
White Adipose Tissue ◽  
Regional Differences ◽  
Sensory Innervation ◽  
Exact Nature ◽  
Total Body Fat ◽  
The Central Nervous System ◽  
Total Body

We review the extensive physiological and neuroanatomical evidence for the innervation of white adipose tissue (WAT) by the sympathetic nervous system (SNS) as well as what is known about the sensory innervation of this tissue. The SNS innervation of WAT appears to be a part of the general SNS outflow from the central nervous system, consisting of structures and connections throughout the neural axis. The innervation of WAT by the SNS could play a role in the regulation of total body fat in general, most likely plays an important role in regional differences in lipid mobilization specifically, and may have a trophic affect on WAT. The exact nature of the SNS innervation of WAT is not known but it may involve contact with adipocytes and/or their associated vasculature. We hypothesize that the SNS innervation of WAT is an important contributor to the apparent “regulation” of total body fat.

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