Alteration in Red Blood Cell Sodium and Potassium Concentrations and Increased Lipid Peroxidation in Patients with Chronic Renal Failure on Maintenance Hemodialysis: A Hypothesis

1994 ◽  
Vol 14 (3) ◽  
pp. 246-248 ◽  
Author(s):  
Dobrin Paskalev ◽  
Pavlina Tchankova ◽  
Tatjana Jankovd ◽  
Michael Steiner ◽  
Dimitir Nenov
Keyword(s):  
Lipid Peroxidation ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Maintenance Hemodialysis ◽  
Sodium And Potassium

scholarly journals Low Alpha-Tocopherol Concentration of Red Blood Cell in Chronic Renal Failure

1985 ◽  
Vol 13 (5) ◽  
pp. 1129-1135
Author(s):  
Kazuo MORI ◽  
Susumu YUKAWA ◽  
Akira HIBINO ◽  
Miyahiko SONOBE ◽  
Osamu NISHIKAWA ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Alpha Tocopherol ◽  
Tocopherol Concentration

scholarly journals Changes in red blood cell membrane structure in patients with chronic renal failure.

1997 ◽  
Vol 44 (1) ◽  
pp. 99-107 ◽  
Author(s):  
K Gwoździński ◽  
M Janicka ◽  
J Brzeszczyńska ◽  
M Luciak
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Membrane Protein ◽  
Blood Cell ◽  
Hydroxyl Radicals ◽  
Red Blood Cell ◽  
Blood Cells ◽  
Membrane Structure ◽  
Osmotic Fragility ◽  
Tert Butylhydroperoxide

The properties of red blood cell membranes in patients with chronic renal failure were investigated using electron paramagnetic resonance spectroscopy. Using spin traps, 5,5-dimethylpirroline-1 oxide and N-tert-butyl-alpha-phenylnitrone, we found generation of hydroxyl radicals in the blood of patients with chronic renal failure after 20 min of regular hemodialysis. The physical state of membrane proteins and membrane osmotic fragility and reductive properties of red blood cells were studied. The increase in the relative correlation time of 4-(2-iodoacetamido)-2,2,6,6-tetramethylpiperidine-1 oxyl indicates the immobilization of membrane protein molecules in erythrocytes of chronic renal failure patients. The decrease in membrane protein mobility was observed in whole blood incubated with tert-butylhydroperoxide, regardless of the presence of iron. We found that the addition of ferrous ions did not aggravate profound changes in membrane proteins induced with tert-butylhydroperoxide. We also demonstrated higher osmotic fragility of erythrocytes in the patients with renal failure as compared to normal subjects. These alterations in membrane structure of red blood cells in hemodialysed patients suggest that hydroxyl radicals generated during hemodialysis can play an important role in the oxidative mechanism of erythrocyte damage.

scholarly journals COVID-19 disease—Temporal analyses of complete blood count parameters over course of illness, and relationship to patient demographics and management outcomes in survivors and non-survivors: A longitudinal descriptive cohort study

PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0244129
Author(s):  
Simone Lanini ◽  
Chiara Montaldo ◽  
Emanuele Nicastri ◽  
Francesco Vairo ◽  
Chiara Agrati ◽  
...  
Keyword(s):  
Renal Failure ◽  
Cohort Study ◽  
Chronic Renal Failure ◽  
Cardiovascular Diseases ◽  
Blood Cell ◽  
Red Blood Cell ◽  
Blood Count ◽  
Time Dependent ◽  
Full Blood Count ◽  
Platelet Volume

Background Detailed temporal analyses of complete (full) blood count (CBC) parameters, their evolution and relationship to patient age, gender, co-morbidities and management outcomes in survivors and non-survivors with COVID-19 disease, could identify prognostic clinical biomarkers. Methods From 29 January 2020 until 28 March 2020, we performed a longitudinal cohort study of COVID-19 inpatients at the Italian National Institute for Infectious Diseases, Rome, Italy. 9 CBC parameters were studied as continuous variables [neutrophils, lymphocytes, monocytes, platelets, mean platelet volume, red blood cell count, haemoglobin concentration, mean red blood cell volume and red blood cell distribution width (RDW %)]. Model-based punctual estimates, as average of all patients’ values, and differences between survivors and non-survivors, overall, and by co-morbidities, at specific times after symptoms, with relative 95% CI and P-values, were obtained by marginal prediction and ANOVA- style joint tests. All analyses were carried out by STATA 15 statistical package. Main findings 379 COVID-19 patients [273 (72% were male; mean age was 61.67 (SD 15.60)] were enrolled and 1,805 measures per parameter were analysed. Neutrophils’ counts were on average significantly higher in non-survivors than in survivors (P<0.001) and lymphocytes were on average higher in survivors (P<0.001). These differences were time dependent. Average platelets’ counts (P<0.001) and median platelets’ volume (P<0.001) were significantly different in survivors and non-survivors. The differences were time dependent and consistent with acute inflammation followed either by recovery or by death. Anaemia with anisocytosis was observed in the later phase of COVID-19 disease in non-survivors only. Mortality was significantly higher in patients with diabetes (OR = 3.28; 95%CI 1.51–7.13; p = 0.005), obesity (OR = 3.89; 95%CI 1.51–10.04; p = 0.010), chronic renal failure (OR = 9.23; 95%CI 3.49–24.36; p = 0.001), COPD (OR = 2.47; 95% IC 1.13–5.43; p = 0.033), cardiovascular diseases (OR = 4.46; 95%CI 2.25–8.86; p = 0.001), and those >60 years (OR = 4.21; 95%CI 1.82–9.77; p = 0.001). Age (OR = 2.59; 95%CI 1.04–6.45; p = 0.042), obesity (OR = 5.13; 95%CI 1.81–14.50; p = 0.002), renal chronic failure (OR = 5.20; 95%CI 1.80–14.97; p = 0.002) and cardiovascular diseases (OR 2.79; 95%CI 1.29–6.03; p = 0.009) were independently associated with poor clinical outcome at 30 days after symptoms’ onset. Interpretation Increased neutrophil counts, reduced lymphocyte counts, increased median platelet volume and anaemia with anisocytosis, are poor prognostic indicators for COVID19, after adjusting for the confounding effect of obesity, chronic renal failure, COPD, cardiovascular diseases and age >60 years.

99mTc-Labelled Red Blood Cell Scintigraphy for Localization of Gastrointestinal Bleeding in Chronic Renal Failure

Nephron ◽  
1998 ◽  
Vol 80 (1) ◽  
pp. 76-78 ◽  
Author(s):  
A. Oliveras ◽  
J. Aubia ◽  
H. Cao ◽  
J.M. Puig ◽  
F. Barbosa ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Blood Cell ◽  
Gastrointestinal Bleeding ◽  
Red Blood Cell

Red blood cell survival in chronic renal failure

2004 ◽  
Vol 44 (4) ◽  
pp. 715-719 ◽  
Author(s):  
Joseph Ly ◽  
Rosa Marticorena ◽  
Sandra Donnelly
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Blood Cell ◽  
Cell Survival ◽  
Red Blood Cell

Summer Camp Hemodialysis for Children With Chronic Renal Failure

PEDIATRICS ◽  
1977 ◽  
Vol 60 (1) ◽  
pp. 46-50
Author(s):  
William A. Primack ◽  
Ira Greifer
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Medical Treatment ◽  
Summer Camp ◽  
Maintenance Hemodialysis ◽  
Self Confidence ◽  
Self Image ◽  
Hemodialysis Unit ◽  
Pediatric Hemodialysis ◽  
Satellite Unit

A hemodialysis unit was established at a rural summer camp for children. Required medical treatment was planned so as to interfere as little as possible with normal camp programs. Campers who require dialysis were mixed fully into the population of normal campers. Twenty-two children participated during the first summer of operation. Our experience indicates that children on maintenance hemodialysis can be integrated with normal peers in a recreational program and can improve their self-image and self-confidence. The program also demonstrates that chronic pediatric hemodialysis can be safely performed in a rural satellite unit.

Sign in / Sign up

Export Citation Format

Share Document