Abnormal Eye Development in Drosophila after Treatment with Vinblastine

Pathobiology ◽  
1983 ◽  
Vol 51 (6) ◽  
pp. 345-351 ◽  
Author(s):  
Alexander Wolsky
Keyword(s):  
Eye Development

Fine structure of the retina of the giant scallop, Placopecten magellanicus

1984 ◽  
Vol 42 ◽  
pp. 312-313
Author(s):  
C.V.L. Powell
Keyword(s):  
Fine Structure ◽  
Electron Microscope ◽  
Light Intensity ◽  
Scanning Electron Microscope ◽  
Eye Development ◽  
Preliminary Observation ◽  
Columnar Epithelium ◽  
Placopecten Magellanicus ◽  
Environmental Light ◽  
Scanning Electron

The overall fine structure of the eye in Placopecten is similar to that of other scallops. The optic tentacle consists of an outer columnar epithelium which is modified into a pigmented iris and a cornea (Fig. 1). This capsule encloses the cellular lens, retina, reflecting argentea and the pigmented tapetum. The retina is divided into two parts (Fig. 2). The distal retina functions in the detection of movement and the proximal retina monitors environmental light intensity. The purpose of the present study is to describe the ultrastructure of the retina as a preliminary observation on eye development. This is also the first known presentation of scanning electron microscope studies of the eye of the scallop.

Etiology of White Spot Defect in Swiss Cheese Made from Pasteurized Milk

1986 ◽  
Vol 49 (9) ◽  
pp. 718-723 ◽  
Author(s):  
K. R. NATH ◽  
B. J. KOSTAK
Keyword(s):  
Eye Development ◽  
Lactobacillus Fermentum ◽  
White Spot ◽  
Co2 Production ◽  
Broth Culture ◽  
Complete Dissolution ◽  
Swiss Cheese ◽  
Streptococcus Faecalis ◽  
Pasteurized Milk ◽  
White Spots

Swiss cheese made from fully pasteurized milk developed white spots during hot room stay. This cheese was bitter and eye development was generally retarded. Streptococcus faecalis subsp. liquefaciens was isolated in high numbers from the spot; it caused bitterness in milk cultures with complete dissolution of the milk clot. The isolate was inhibitory to propionibacteria and Lactobacillus fermentum; CO2 production by Propionibacterium was depressed in broth culture in the presence of the S. faecalis subsp. liquefaciens isolate.

BMP 7 Is Required for Nephrogenesis, Eye Development, and Skeletal Patterninga

1996 ◽  
Vol 785 (1) ◽  
pp. 98-107 ◽  
Author(s):  
Gerard Karsenty ◽  
Guangbin Luo ◽  
Clementine Hofmann ◽  
Allan Bradley
Keyword(s):  
Eye Development

scholarly journals A Novel Mutation in Cse1l Disrupts Brain and Eye Development with Specific Effects on Pax6 Expression

2021 ◽  
Vol 9 (3) ◽  
pp. 27
Author(s):  
Lauren E. Blizzard ◽  
Chelsea Menke ◽  
Shaili D. Patel ◽  
Ronald R. Waclaw ◽  
Salil A. Lachke ◽  
...  
Keyword(s):  
Neural Development ◽  
Null Allele ◽  
Eye Development ◽  
Novel Mutation ◽  
Forward Genetics ◽  
Mammalian Development ◽  
Variants Of Unknown Significance ◽  
New Genes ◽  
Conditional Allele ◽  
Sequencing Studies

Forward genetics in the mouse continues to be a useful and unbiased approach to identifying new genes and alleles with previously unappreciated roles in mammalian development and disease. Here, we report a new mouse allele of Cse1l that was recovered from an ENU mutagenesis screen. Embryos homozygous for the anteater allele of Cse1l display a number of variable phenotypes, with craniofacial and ocular malformations being the most obvious. We provide evidence that Cse1l is the causal gene through complementation with a novel null allele of Cse1l generated by CRISPR-Cas9 editing. While the variability in the anteater phenotype was high enough to preclude a detailed molecular analysis, we demonstrate a very penetrant reduction in Pax6 levels in the developing eye along with significant ocular developmental phenotypes. The eye gene discovery tool iSyTE shows Cse1l to be significantly expressed in the lens from early eye development stages in embryos through adulthood. Cse1l has not previously been shown to be required for organogenesis as homozygosity for a null allele results in very early lethality. Future detailed studies of Cse1l function in craniofacial and neural development will be best served with a conditional allele to circumvent the variable phenotypes we report here. We suggest that human next-generation (whole genome or exome) sequencing studies yielding variants of unknown significance in CSE1L could consider these findings as part of variant analysis.

scholarly journals Expression ofXenopus laevis Lhx2 during eye development and evidence for divergent expression among vertebrates

2006 ◽  
Vol 235 (4) ◽  
pp. 1133-1141 ◽  
Author(s):  
Andrea S. Viczian ◽  
Anne G. Bang ◽  
William A. Harris ◽  
Michael E. Zuber
Keyword(s):  
Eye Development
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