scholarly journals Dominant Drop Mutants Are Gain-of-Function Alleles of the muscle segment homeobox Gene (msh) Whose Overexpression Leads to the Arrest of Eye Development

2001 ◽  
Vol 233 (2) ◽  
pp. 380-393 ◽  
Author(s):  
Brian A Mozer
Keyword(s):  
Eye Development ◽  
Homeobox Gene ◽  
Gain Of Function

Identifying targets of the rough homeobox gene of Drosophila: evidence that rhomboid functions in eye development

Development ◽  
1992 ◽  
Vol 116 (2) ◽  
pp. 335-346 ◽  
Author(s):  
M. Freeman ◽  
B.E. Kimmel ◽  
G.M. Rubin
Keyword(s):  
Cell Fate ◽  
Target Genes ◽  
Eye Development ◽  
Expression Patterns ◽  
Ectopic Expression ◽  
Homeobox Gene ◽  
Homeodomain Protein ◽  
Dorsoventral Patterning ◽  
Altered Expression ◽  
Enhancer Trap Lines

In order to identify potential target genes of the rough homeodomain protein, which is known to specify some aspects of the R2/R5 photoreceptor subtype in the Drosophila eye, we have carried out a search for enhancer trap lines whose expression is rough-dependent. We crossed 101 enhancer traps that are expressed in the developing eye into a rough mutant background, and have identified seven lines that have altered expression patterns. One of these putative rough target genes is rhomboid, a gene known to be required for dorsoventral patterning and development of some of the nervous system in the embryo. We have examined the role of rhomboid in eye development and find that, while mutant clones have only a subtle phenotype, ectopic expression of the gene causes the non-neuronal mystery cells to be transformed into photoreceptors. We propose that rhomboid is a part of a partially redundant network of genes that specify photoreceptor cell fate.

Use of Gain-of-Function Study to Delineate the Roles of crumbs in Drosophila Eye Development

2003 ◽  
Vol 10 (6) ◽  
pp. 766-773 ◽  
Author(s):  
Seng-Sheen Fan ◽  
Mei-Sue Chen ◽  
Jui-Fen Lin ◽  
Wei-Ting Chao ◽  
Vivian Cheng Yang
Keyword(s):  
Eye Development ◽  
Gain Of Function ◽  
Function Study

scholarly journals The Dominant MutationGlazedIs a Gain-of-Function Allele ofwinglessThat, Similar to Loss of APC, Interferes with Normal Eye Development

1999 ◽  
Vol 206 (2) ◽  
pp. 178-188 ◽  
Author(s):  
Erich Brunner ◽  
Damian Brunner ◽  
Weimin Fu ◽  
Ernst Hafen ◽  
Konrad Basler
Keyword(s):  
Eye Development ◽  
Gain Of Function

The Rx homeobox gene is essential for vertebrate eye development

Nature ◽  
10.1038/42475 ◽  
1997 ◽  
Vol 387 (6633) ◽  
pp. 603-607 ◽  
Author(s):  
P. H. Mathers ◽  
A. Grinberg ◽  
K. A. Mahon ◽  
M. Jamrich
Keyword(s):  
Eye Development ◽  
Homeobox Gene ◽  
Vertebrate Eye

Use of gain-of-function study to delineate the roles ofcrumbs inDrosophila eye development

2003 ◽  
Vol 10 (6) ◽  
pp. 766-773
Author(s):  
Seng-Sheen Fan ◽  
Mei-Sue Chen ◽  
Jui-Fen Lin ◽  
Wei-Ting Chao ◽  
Vivian Cheng Yang
Keyword(s):  
Eye Development ◽  
Gain Of Function ◽  
Function Study

scholarly journals Isolation of a Drosophila homolog of the vertebrate homeobox gene Rx and its possible role in brain and eye development

1998 ◽  
Vol 95 (5) ◽  
pp. 2343-2348 ◽  
Author(s):  
T. Eggert ◽  
B. Hauck ◽  
N. Hildebrandt ◽  
W. J. Gehring ◽  
U. Walldorf
Keyword(s):  
Eye Development ◽  
Homeobox Gene ◽  
Drosophila Homolog

Fine structure of the retina of the giant scallop, Placopecten magellanicus

1984 ◽  
Vol 42 ◽  
pp. 312-313
Author(s):  
C.V.L. Powell
Keyword(s):  
Fine Structure ◽  
Electron Microscope ◽  
Light Intensity ◽  
Scanning Electron Microscope ◽  
Eye Development ◽  
Preliminary Observation ◽  
Columnar Epithelium ◽  
Placopecten Magellanicus ◽  
Environmental Light ◽  
Scanning Electron

The overall fine structure of the eye in Placopecten is similar to that of other scallops. The optic tentacle consists of an outer columnar epithelium which is modified into a pigmented iris and a cornea (Fig. 1). This capsule encloses the cellular lens, retina, reflecting argentea and the pigmented tapetum. The retina is divided into two parts (Fig. 2). The distal retina functions in the detection of movement and the proximal retina monitors environmental light intensity. The purpose of the present study is to describe the ultrastructure of the retina as a preliminary observation on eye development. This is also the first known presentation of scanning electron microscope studies of the eye of the scallop.

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