Adrenergic and Peptidergic (Substance P and Vasoactive Intestinal Polypeptide) Innervation of the Rat Portal Vein

1982 ◽  
Vol 19 (5) ◽  
pp. 263-272 ◽  
Author(s):  
Francisco Barja ◽  
Ron Mathison
Keyword(s):  
Substance P ◽  
Portal Vein ◽  
Vasoactive Intestinal Polypeptide ◽  
Rat Portal Vein ◽  
Intestinal Polypeptide

scholarly journals Innervation of the pancreas by substance P, enkephalin, vasoactive intestinal polypeptide and gastrin/CCK immunoractive nerves.

1979 ◽  
Vol 27 (9) ◽  
pp. 1283-1284 ◽  
Author(s):  
L I Larsson
Keyword(s):  
Blood Flow ◽  
Insulin Secretion ◽  
Substance P ◽  
Blood Vessels ◽  
Vasoactive Intestinal Polypeptide ◽  
Pancreatic Blood Flow ◽  
Major Site ◽  
Site Of Action ◽  
Immunocytochemical Studies ◽  
Intestinal Polypeptide

Immunocytochemical studies habe shown that many peptides which profoundly affect the endocrine and exocrine functions of the pancreas are localized to neurons. In the cat, such peptidergic nerves appear to innervate ganglia, islets and blood vessels of the pancreas, whereas their contributions to exocrine cells are minor. Our studies suggest that pancreatic ganglia represent one major site of action of the peptides and that, in addition, nerves containing the vasoactive intestinal polypeptide and gastrin/CCK-related peptides profoundly affect pancreatic blood flow and insulin secretion, respectively.

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