Morphometric and Stereological Study of the Glandular Epithelium of the Seminal Vesicle of Castrated Guinea Pigs Treated with 17β-Oestradiol Benzoate

1993 ◽  
Vol 148 (4) ◽  
pp. 181-188
Author(s):  
C.C. Tarn ◽  
Y.C. Wong
Keyword(s):  
Seminal Vesicle ◽  
Guinea Pigs ◽  
Glandular Epithelium ◽  
Oestradiol Benzoate

LACK OF EFFECT OF TREATMENT WITH OESTROGEN IN ADVANCING PUBERTY IN THE GUINEA-PIG

1982 ◽  
Vol 92 (2) ◽  
pp. 267-271 ◽  
Author(s):  
L. CALIGARIS ◽  
B. T. DONOVAN
Keyword(s):  
Guinea Pig ◽  
Guinea Pigs ◽  
Oestradiol Benzoate ◽  
Effect Of Treatment

Guinea-pigs were injected with 500 ng oestradiol benzoate or 0·1 ml arachis oil at 0, 5, 10, 20 or 25 days of age, or 2 μg oestradiol benzoate/100 g body wt at 25 days, in order to determine whether puberty would be advanced, as in the rat. It was not. Repeated injections of 100 ng oestradiol benzoate or 0·1 ml arachis oil for 5 days beginning at 0, 10, 20 or 25 days of age, or 2 μg oestradiol benzoate/100 g body wt beginning at 25 days, were similarly ineffective.

scholarly journals Immunohistochemical Characteristics of Estrogen Receptor .ALPHA. Positive Cells in Glandular Epithelium of the Rat Seminal Vesicle.

1999 ◽  
Vol 187 (1) ◽  
pp. 25-35 ◽  
Author(s):  
Hisako Yuasa ◽  
Yoshitatsu Fukabori ◽  
Yoshihiro Ono ◽  
Nao Tomita ◽  
Keiji Suzuki ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Seminal Vesicle ◽  
Estrogen Receptor Alpha ◽  
Glandular Epithelium ◽  
Receptor Alpha ◽  
Rat Seminal Vesicle

OESTROGEN AND PROGESTERONE AND THE FUNCTION OF THE CORPORA LUTEA IN THE GUINEA-PIG

1970 ◽  
Vol 47 (2) ◽  
pp. 225-230 ◽  
Author(s):  
K. P. BLAND ◽  
B. T. DONOVAN
Keyword(s):  
Guinea Pig ◽  
Guinea Pigs ◽  
Single Injection ◽  
Glass Beads ◽  
Oestrous Cycle ◽  
Corpora Lutea ◽  
Luteal Regression ◽  
Oestradiol Benzoate

SUMMARY Regression of the corpora lutea in the guinea-pig could be accelerated by treatment with 10 μg. oestradiol benzoate daily over days 3–11 of the oestrous cycle. A single injection of 10 μg. oestradiol benzoate on day 3 was also effective. The luteolytic effect of oestrogen was abolished by hysterectomy, indicating that the uterus is involved in the mediation of the response. Progesterone (5 mg. daily over days 3–11) enhanced the luteal regression brought about by the presence of two glass beads in one horn of the uterus, but did not affect luteal size in otherwise intact females. Treatment of guinea-pigs with 5 mg. progesterone daily over days 2–5 or 4–7 failed to alter the length of the oestrous cycle.

THE EFFECT OF OESTRADIOL ON THE RESPONSE OF HYPOPHYSECTOMIZED GUINEA-PIGS TO ADRENOCORTICOTROPHIN

1959 ◽  
Vol 19 (3) ◽  
pp. 241-250 ◽  
Author(s):  
R. V. BROOKS ◽  
BARBARA E. CLAYTON ◽  
JANET M. WORDEN
Keyword(s):  
Urinary Excretion ◽  
Pituitary Gland ◽  
Guinea Pigs ◽  
Oestradiol Benzoate

SUMMARY 1. A method is described for the preparation and maintenance of hypophysectomized guinea-pigs. 2. Following hypophysectomy the response of female guinea-pigs to adrenocorticotrophin (ACTH) as measured by the urinary excretion of 17-ketosteroids (KS) and 17-ketogenic steroids (KGS) was reduced by 53% for KS and 59% for KGS. The decreased response was seen as early as 1 week after operation. 3. In the absence of the pituitary gland, oestradiol benzoate did not modify the response to administered ACTH as measured by the urinary excretion of KS and KGS.

EFFECT OF ANAESTHESIA ON THE NEGATIVE FEEDBACK ACTION OF GONADAL STEROIDS ON GONADOTROPHIN SECRETION IN THE OVARIECTOMIZED GUINEA-PIG

1981 ◽  
Vol 89 (1) ◽  
pp. 167-177 ◽  
Author(s):  
M. J. KILPATRICK ◽  
B. T. DONOVAN
Keyword(s):  
Guinea Pig ◽  
Guinea Pigs ◽  
Experimental Conditions ◽  
Feedback Effects ◽  
Gonadotrophin Secretion ◽  
Serial Sampling ◽  
Oestradiol Benzoate ◽  
The Mean ◽  
Lh Secretion ◽  
Conscious Animals

The effects of urethane or sodium pentobarbitone anaesthesia on the feedback effects of oestradiol or progesterone on gonadotrophin secretion in the ovariectomized guinea-pig have been investigated. In the control experiments in which no steroids or vehicles were given the concentration of LH and FSH in samples of peripheral blood collected at intervals of 15 min varied in a random episodic manner. The mean level of LH was significantly greater in sodium pentobarbitone- and urethane-anaesthetized animals when compared with conscious animals, and in the conscious animals there was a progressive fall in mean LH level during the course of serial sampling. This effect was not observed in anaesthetized animals. Oestradiol benzoate (2 μg s.c.) inhibited LH secretion in conscious animals and in those anaesthetized with sodium pentobarbitone, but not in urethane-anaesthetized guinea-pigs. Progesterone (200 μg s.c.) progressively depressed plasma LH levels in conscious and urethane-anaesthetized animals, but not in guinea-pigs anaesthetized with sodium pentobarbitone. The effect of anaesthesia was the converse of that observed with oestradiol treatment. Significant changes in FSH secretion were not observed under any experimental conditions. These findings point to the existence of a mechanism in spayed guinea-pigs that restrains LH secretion, the action of which is reduced by anaesthesia and modified by oestradiol and progesterone.

Investigation of the relaxant effects of propofol on ovalbumin-induced asthma in guinea pigs

2006 ◽  
pp. 1
Author(s):  
I. Bagcivan ◽  
O. Cevit ◽  
M. K. Yildirim ◽  
S. Gursoy ◽  
S. Yildirim ◽  
...  
Keyword(s):  
Guinea Pigs

Electron Microscopic Study of the Epithelium of the Seminal Vesicle of Aging Rats

1974 ◽  
Vol 32 ◽  
pp. 138-139
Author(s):  
V. F. Allison ◽  
G. C. Fink ◽  
G. W. Cearley
Keyword(s):  
Cell Growth ◽  
Epithelial Cell ◽  
Epithelial Cells ◽  
Seminal Vesicle ◽  
Seminal Vesicles ◽  
Epithelial Layer ◽  
Epithelial Hyperplasia ◽  
Electron Microscopic ◽  
Aging Rats ◽  
Pseudostratified Epithelium

It is well known that epithelial hyperplasia (benign hypertrophy) is common in the aging prostate of dogs and man. In contrast, little evidence is available for abnormal epithelial cell growth in seminal vesicles of aging animals. Recently, enlarged seminal vesicles were reported in senescent mice, however, that enlargement resulted from increased storage of secretion in the lumen and occurred concomitant to epithelial hypoplasia in that species.The present study is concerned with electron microscopic observations of changes occurring in the pseudostratified epithelium of the seminal vescles of aging rats. Special attention is given to certain non-epithelial cells which have entered the epithelial layer.

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