AXON-MYELIN RELATIONSHIPS IN PERIPHERAL NERVE FIBRES

1958 ◽  
Vol 33 (1-2) ◽  
pp. 1-37 ◽  
Author(s):  
S. Sunderland ◽  
A.F. Roche
Keyword(s):  
Peripheral Nerve ◽  
Nerve Fibres

scholarly journals Unravelling crucial biomechanical resilience of myelinated peripheral nerve fibres provided by the Schwann cell basal lamina and PMP22

2014 ◽  
Vol 4 (1) ◽  
Author(s):  
Gonzalo Rosso ◽  
Ivan Liashkovich ◽  
Burkhard Gess ◽  
Peter Young ◽  
Alejandra Kun ◽  
...  
Keyword(s):  
Schwann Cell ◽  
Peripheral Nerve ◽  
Basal Lamina ◽  
Nerve Fibres

scholarly journals Action of Various Poisons upon nerve-fibres and Peripheral nerve-cells

1890 ◽  
Vol 11 (suppl) ◽  
pp. 509-527 ◽  
Author(s):  
J. N. Langley ◽  
W. Lee Dickinson
Keyword(s):  
Peripheral Nerve ◽  
Nerve Cells ◽  
Nerve Fibres

Trigeminal trophic syndrome: Analysis of the number of peripheral nerve fibres and blood vessels in the lesional skin

2017 ◽  
Vol 59 (1) ◽  
pp. 59-61 ◽  
Author(s):  
Akihiko Uchiyama ◽  
Sei-ichiro Motegi ◽  
Chisako Fujiwara ◽  
Akiko Sekiguchi ◽  
Masahito Yasuda ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Blood Vessels ◽  
Nerve Fibres ◽  
Lesional Skin ◽  
Trigeminal Trophic Syndrome ◽  
Syndrome Analysis

scholarly journals Morphometric and ultrastructural changes with ageing in mouse peripheral nerve

1999 ◽  
Vol 195 (4) ◽  
pp. 563-576
Author(s):  
DOLORES CEBALLOS ◽  
JORDI CUADRAS ◽  
ENRIQUE VERDÚ ◽  
XAVIER NAVARRO
Keyword(s):  
Peripheral Nerve ◽  
Morphological Changes ◽  
Quantitative Information ◽  
Unmyelinated Axon ◽  
Ultrastructural Changes ◽  
Myelinated Fibre ◽  
Nerve Fibres ◽  
Internodal Length ◽  
Myelinated Fibres ◽  
Ageing Period

Qualitative and quantitative information is reported on the morphological changes that occur in nerve fibres and nonneuronal cells of peripheral nerve during the lifetime of the mouse. Tibial nerves of mice aged 6–33 mo were studied. With ageing, collagen accumulates in the perineurium and lipid droplets in the perineurial cells. Macrophages and mast cells increase in number, and onion bulbs and collagen pockets are frequently present. Schwann cells associated with myelinated fibres (MF) slightly decrease in number in parallel with an increase of the internodal length from 6 to 12 mo, but increase in older nerves when demyelination and remyelination are common. The unmyelinated axon to myelinated fibre (UA/MF) ratio was about 2 until 12 mo, decreasing to 1.6 by 27 mo. In older mice, the loss of nerve fibres involves UA (50% loss of 27–33 mo cf. 6 mo) more markedly than MF (35%). In aged nerves wide incisures and infolded or outfolded myelin loops are frequent, resulting in an increased irregularity in the morphology of fibres along the internodes. In the mouse there is an adult time period, 12–20 mo, during which several features of degeneration progressively appear, and an ageing period from 20 mo upwards when the nerve suffers a general disorganisation and marked fibre loss.

The Distribution of Electron-Dense Tracers in Peripheral Nerve Fibres

1971 ◽  
Vol 8 (2) ◽  
pp. 541-555
Author(s):  
SUSAN M. HALL ◽  
P. L. WILLIAMS
Keyword(s):  
Schwann Cell ◽  
Peripheral Nerve ◽  
Myelin Sheath ◽  
External Surface ◽  
Nerve Fibres ◽  
Cell Cytoplasm ◽  
Line Region ◽  
Periaxonal Space

Two electron-dense tracers, ferritin and lanthanum, have been administered to peripheral nerve fibres, and their uptake has been studied ultrastructurally. It was found that the perineurium was an effective barrier to ferritin in vivo, and the tracer was subsequently injected sub-perineurially. Ferritin uptake over a 120-min period was confined to occasional phagocytic vesicles in perineurial and Schwann cells, and to the nodal gap substance and paranodal periaxonal space. No uptake was observed in the myelin sheath, incisural intraperiod line gap, or in the axoplasm. Soaking fibres in ferritin in vitro resulted in a more generalized cytoplasmic and axoplasmic uptake, although the myelin sheath and Schmidt-Lanterman incisures remained devoid of the tracer. Lanthanum nitrate, included in the fixative solution, delineated the patent incisural intraperiod line gap, and outlined the external surface of the terminal loops of nodal Schwann cell cytoplasm, and the paranodal Schwann cell-axolemmal junction. Unlike ferritin, La3+ penetrated the myelin sheath, being usually confined to the intraperiod line region of the outer lamellae, where it was associated with a widening of the lamellar unit, and an apparent splitting of the intraperiod line. The results are discussed with regard to distribution of extracellular space in peripheral nerve fibres.

Atypical Spindles in Reinnervated Rat Muscles

Development ◽  
1961 ◽  
Vol 9 (3) ◽  
pp. 456-467
Author(s):  
P. Hník ◽  
J. Zelená
Keyword(s):  
Peripheral Nerve ◽  
Functional Groups ◽  
Transition Period ◽  
Present Report ◽  
Sensory Nerve ◽  
Morphological Characteristics ◽  
Muscle Spindles ◽  
Nerve Fibres ◽  
Muscle Receptors ◽  
Short Transition

In young rats, following lesions of a peripheral nerve at birth, immature muscle spindles disintegrate during a short transition period (Zelená, 1957), and even after several months of reinnervation the reinnervated muscles are usually found to contain no spindles (Zelená & Hník, 1960). Nevertheless, occasional small spindles of atypical structure are observed in some of these muscles. In the present report, the structure and morphological characteristics of these atypical spindles were studied and compared with normal spindles. Since differences in fast and slow muscles may include differences in muscle receptors (Voss, 1937; Maruseva, 1947; Hagbarth & Wohlfahrt, 1952; Freimann, 1953; Cooper, 1960), the number, size, and distribution of spindles were studied in two muscles representing the two functional groups. The origin of atypical spindles in the reinnervated muscles is not clear. These spindles could either differentiate anew under the influence of regenerating sensory nerve fibres, or they could originate from spindles reinnervated before their ultimate disintegration had taken place.

scholarly journals Quantitative study of the non-circularity of myelinated peripheral nerve fibres in the cat

1980 ◽  
Vol 308 (1) ◽  
pp. 99-123 ◽  
Author(s):  
Elinor R. Arbuthnott ◽  
Kathleen J. Ballard ◽  
I. A. Boyd ◽  
K. U. Kalu
Keyword(s):  
Peripheral Nerve ◽  
Quantitative Study ◽  
Nerve Fibres
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