Protein Binding of Indomethacin: Binding of Indomethacin to Human Plasma Albumin and its Displacement from Binding by Ibuprofen, Phenylbutazone and Salicylate, in vitro

Pharmacology ◽  
1974 ◽  
Vol 12 (1) ◽  
pp. 12-19 ◽  
Author(s):  
R.W. Mason ◽  
E.G. McQueen
Keyword(s):  
Protein Binding ◽  
Human Plasma ◽  
Plasma Albumin

Protein binding of fentanyl and its metabolite nor-fentanyl in human plasma, albumin andα-1 acid glycoprotein

Xenobiotica ◽  
2014 ◽  
Vol 45 (3) ◽  
pp. 207-212 ◽  
Author(s):  
Sudeep Raj Bista ◽  
Alison Haywood ◽  
Janet Hardy ◽  
Michael Lobb ◽  
Angela Tapuni ◽  
...  
Keyword(s):  
Protein Binding ◽  
Human Plasma ◽  
Plasma Albumin ◽  
Acid Glycoprotein

scholarly journals In Vitro Bactericidal Activity of Iclaprim in Human Plasma

2009 ◽  
Vol 53 (10) ◽  
pp. 4542-4544 ◽  
Author(s):  
Heike Laue ◽  
Tiziana Valensise ◽  
Aurélie Seguin ◽  
Sergio Lociuro ◽  
Khalid Islam ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Protein Binding ◽  
Human Plasma ◽  
Bactericidal Activity ◽  
The Novel

ABSTRACT This study evaluated the effect of human plasma on the in vitro bactericidal activity of the novel diaminopyrimidine iclaprim against methicillin (meticillin)-susceptible and -resistant Staphylococcus aureus strains. MICs and minimal bactericidal concentrations (MBCs) of iclaprim, with ∼93% protein binding, were similar in the absence and in the presence of 50% human plasma; MICs and MBCs ranged from 0.06 to 0.125 μg/ml. Furthermore, the activity of iclaprim was not affected by plasma, with ≥99.9% reduction in CFU after 5.0 to 7.6 h.

Comparative hydrolysis and plasma protein binding of cis-platin and carboplatin in human plasma in vitro

Metallomics ◽  
2011 ◽  
Vol 3 (1) ◽  
pp. 49-55 ◽  
Author(s):  
Melani Sooriyaarachchi ◽  
Aru Narendran ◽  
Jürgen Gailer
Keyword(s):  
Protein Binding ◽  
Human Plasma ◽  
Plasma Protein Binding ◽  
Plasma Protein

scholarly journals In Vitro Protein Binding of Liraglutide in Human Plasma Determined by Reiterated Stepwise Equilibrium Dialysis

2013 ◽  
Vol 102 (8) ◽  
pp. 2882-2888 ◽  
Author(s):  
Anne Plum ◽  
Lisbeth Bjerring Jensen ◽  
Jesper Bøggild Kristensen
Keyword(s):  
Protein Binding ◽  
Human Plasma ◽  
Equilibrium Dialysis ◽  
Vitro Protein

The effect of anti-inflammatory drugs on the protein-binding of [1,2-3H] cortisol in human plasma in vitro

1971 ◽  
Vol 23 (2) ◽  
pp. 145-146 ◽  
Author(s):  
J. B. Stenlake ◽  
W. D. Williams ◽  
A. G. Davidson ◽  
W. W. Downie
Keyword(s):  
Protein Binding ◽  
Human Plasma ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

The effect of anti-inflammatory drugs on the protein-binding of 11-hydroxysteroids in human plasma in vitro

1969 ◽  
Vol 21 (7) ◽  
pp. 451-459 ◽  
Author(s):  
J. B. STENLAKE ◽  
W. D. WILLIAMS ◽  
A. G. DAVIDSON ◽  
W. DOWNIE ◽  
K. WHALEY
Keyword(s):  
Protein Binding ◽  
Human Plasma ◽  
Inflammatory Drugs ◽  
Anti Inflammatory
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