In situ hybridization to human chromosome 1 of a cDNA probe for the gene encoding the basement membrane heparan sulfate proteoglycan (HSPG)

1990 ◽  
Vol 54 (1-2) ◽  
pp. 60-61 ◽  
Author(s):  
R.F. Wintle ◽  
R. Kisilevsky ◽  
D. Noonan ◽  
A.M.V. Duncan
1997 ◽  
Vol 79 (1-2) ◽  
pp. 143-144 ◽  
Author(s):  
J. Aurich-Costa ◽  
S. Cadel ◽  
C. Gouzy ◽  
T. Foulon ◽  
D. Chérif ◽  
...  

1977 ◽  
Vol 36 (1) ◽  
pp. 25-33 ◽  
Author(s):  
Dale M. Steffensen ◽  
Ernest H. Y. Chu ◽  
David P. Speert ◽  
Patrick M. Wall ◽  
Karen Meilinger ◽  
...  

1987 ◽  
Vol 165 (6) ◽  
pp. 1731-1736 ◽  
Author(s):  
D M Lublin ◽  
R S Lemons ◽  
M M Le Beau ◽  
V M Holers ◽  
M L Tykocinski ◽  
...  

Delay-accelerating factor (DAF) protects host cells from complement-mediated damage by regulating the activation of C3 convertases on host cell surfaces. Using a panel of hamster-human somatic cell hybrids, the DAF gene was mapped to human chromosome 1. In situ hybridization studies using human metaphase cells further localized the gene to bands 1q31-41, with the largest cluster of grains at 1q32. This establishes the close linkage of the DAF gene to genes for four other proteins (C3b/C4b receptor or complement receptor 1, C3d receptor or complement receptor 2, factor H, and C4-binding protein) that share 60-amino-acid homologous repeats as well as complement-regulatory or -receptor activity, thereby enlarging the complement-regulatory gene family on the long arm of human chromosome 1.


2000 ◽  
Vol 90 (3-4) ◽  
pp. 253-254 ◽  
Author(s):  
P. Liénard ◽  
M. Rivière ◽  
P. van Vooren ◽  
C. Szpirer ◽  
J. Szpirer

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