Pepsinogens: new variant and linkage relationships to chromosome 6 markers

1978 ◽  
Vol 22 (1-6) ◽  
pp. 301-303 ◽  
Author(s):  
T. Gedde-Dahl, Jr. ◽  
L. Korsnes ◽  
E. Thorsby ◽  
B. Olaisen ◽  
A. Bratlie ◽  
...  
Genomics ◽  
1993 ◽  
Vol 17 (2) ◽  
pp. 324-329 ◽  
Author(s):  
P.A. Clamp ◽  
R. Feltes ◽  
D. Shalhevet ◽  
J.E. Beever ◽  
E. Atac ◽  
...  

Genetics ◽  
1980 ◽  
Vol 96 (3) ◽  
pp. 697-710 ◽  
Author(s):  
M M Goodman ◽  
C W Stuber ◽  
K Newton ◽  
H H Weissinger

ABSTRACT Linkage relationships of 19 enzyme loci have been examined. The chromosomal locations of eight of these loci are formally reported for the first time in this paper. These localizations should assist in the construction of additional useful chromosome marker stocks, especially since several of these enzyme loci lie in regions that were previously poorly mapped. Six loci are on the long arm of chromosome 1. The arrangement is (centromere)—Mdh4-mmm-Pgm1-Adh1-Phi-Gdh1, with about 46% recombination between Mdh4 and Gdh1.—Linkage studies with a2 and pr have resulted in the localization of four enzyme genes to chromosome 5 with arrangement Pgm2-Mdh5-Got3-a2-(centromere)-pr-Got2. Pgm2 lies approximately 35 map units distal to a2 in a previously unmapped region of the short arm of 5, beyond ameiotic.—Approximately 23% recombination was observed between Mdh4 and Pgm1 on chromosome 1, while 17% recombination occurred between Mdh5 and Pgm2 on chromosome 5. Similarly, linkages between Idh1 and Mdh1, about 22 map units apart on chromosome 8, and between Mdh2 and Idh2, less than 5 map units apart on chromosome 6, were observed. Thus, segments of chromosomes 1 and 5 and segments of 6 and 8 may represent duplications on nonhomologous chromosomes.


2001 ◽  
Vol 120 (5) ◽  
pp. A121-A122
Author(s):  
T EZAKI ◽  
M WATANABE ◽  
S FUNAKOSHI ◽  
M NAGANUMA ◽  
T AZUMA ◽  
...  

Praxis ◽  
2002 ◽  
Vol 91 (27) ◽  
pp. 1151-1160
Author(s):  
Fajfr ◽  
Müller

Les maladies thyroïdiennes auto-immunes ou immunes (autoimmune thyroid disease, AITD) sont relativement fréquentes. Le terme de AITD comprend les thyréodites euthyroidiennes ou hypothyroïdiennes de Hashimoto avec ou sans goitre, les hyperthyroïdies classiques de Basedow et leurs variantes nettement plus rares euthyroïdiennes ou hypothyroïdiennes. Aucune des nombreuses classifications des AITD n'a pu s'imposer sur le plan international. La pathogénèse de toutes les formes d'AITD comprend une perturbation de la tolérance immune chez les individus prédisposés génétiquement (séquence HLA-DQAI*0501 sur le bras court du chromosome 6) qui provoque un processus auto-immun contre la glande thyroïdienne. Ces processus sont soit destructeurs ou inhibiteurs, soit stimulateurs, ce qui permet d'expliquer les formes très différentes de AITD. Dans de cas rares, ces processus peuvent se contrebalancer («balance hypotheseis»). Les anticorps anti-récepteurs TPO et TSH (TRAK) ont une place particulière dans le diagnostic des AITD. Les dosages de routine utilisent pour la mesure des TRAK des récepteurs qui ne peuvent pas différencier entre les anticorps stimulants ou bloquants contre les récepteurs TSH. C'est, entre autre pour ces raisons, que les résultats d'anticorps positifs ne sont utilisables qu'en connaissance de la clinique et / ou des paramètres de la fonction thyroïdienne. Ce travail présente quatre patients avec des formes plus complexes d'AITD et résume les connaissances actuelles.


Author(s):  
Andreas Voß ◽  
Klaus Rothermund ◽  
Dirk Wentura

Abstract. In this article, a modified variant of the Affective Simon Task (AST; De Houwer & Eelen, 1998 ) is presented as a measure of implicit evaluations of single stimuli. In the AST, the words “good” or “bad” have to be given as responses depending on the color of the stimuli. The AST was combined with an evaluation task to increase the salience of the valence of the presented stimuli. Experiment 1 investigated evaluations of schematic faces showing emotional expressions. In Experiment 2 we measured the valence of artificial stimuli that acquired valence in a game context during the experiment. Both experiments confirm the validity of the modified AST. The results also revealed a dissociation between explicit and implicit evaluations.


2012 ◽  
pp. 41-66 ◽  
Author(s):  
M. Storchevoy

The paper deals with development of a general theory of the firm. It discusses the demand for such a theory, reviews existing approaches to its generalization, and offers a new variant of general theory of the firm based on the contract theory. The theory is based on minimization of opportunistic behaviour determined by the material structure of production (a classification of ten structural factors is offered). This framework is applied to the analysis of three boundaries problems (boundaries of the job, boundaries of the unit, boundaries of the firm) and five integration dilemmas (vertical, horizontal, functional, related, and conglomerate).


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