Somatic cell genetic evidence for the presence of a gene for citrullinemia on human chromosome 9

1977 ◽  
Vol 19 (1) ◽  
pp. 44-48 ◽  
Author(s):  
B. Carritt
1982 ◽  
Vol 155 (4) ◽  
pp. 1019-1024 ◽  
Author(s):  
D L Slate ◽  
P D'Eustachio ◽  
D Pravtcheva ◽  
A C Cunningham ◽  
S Nagata ◽  
...  

To determine the chromosomal location of the human alpha interferon genes, we scored a series of human/rodent somatic cell hybrids for the presence of DNA sequences hybridizing to an alpha 1 interferon DNA probe. The presence of human chromosome 9 in a hybrid correlated with the presence of a family of alpha interferon genes.


1982 ◽  
Vol 2 (5) ◽  
pp. 564-570
Author(s):  
P M Pitha ◽  
D L Slate ◽  
N B Raj ◽  
F H Ruddle

The human fibroblast interferon gene beta 1 was mapped to human chromosome 9. Sequence homology with a beta 1 cDNA clone was detected in both genomic DNA and induced mRNA of human/mouse or human/hamster somatic cell hybrids containing human chromosome 9, but not in lines lacking this chromosome or those retaining a complex translocation involving chromosomes 9 and 11. Interferon mRNA that did not share sequence homology with the beta 1 cDNA clone was detected in lines containing human chromosomes 2 and 5 but lacking chromosome 9, suggesting the presence of other unlinked interferon sequences in the human genome.


1994 ◽  
Vol 20 (5) ◽  
pp. 391-400 ◽  
Author(s):  
Bruce W. Porterfield ◽  
Olufunmilayo I. Olopade ◽  
Janet D. Rowley ◽  
Manuel O. Diaz

Nature ◽  
1976 ◽  
Vol 259 (5545) ◽  
pp. 665-667 ◽  
Author(s):  
V. M. CHAPMAN ◽  
T. B. SHOWS

1982 ◽  
Vol 2 (5) ◽  
pp. 564-570 ◽  
Author(s):  
P M Pitha ◽  
D L Slate ◽  
N B Raj ◽  
F H Ruddle

The human fibroblast interferon gene beta 1 was mapped to human chromosome 9. Sequence homology with a beta 1 cDNA clone was detected in both genomic DNA and induced mRNA of human/mouse or human/hamster somatic cell hybrids containing human chromosome 9, but not in lines lacking this chromosome or those retaining a complex translocation involving chromosomes 9 and 11. Interferon mRNA that did not share sequence homology with the beta 1 cDNA clone was detected in lines containing human chromosomes 2 and 5 but lacking chromosome 9, suggesting the presence of other unlinked interferon sequences in the human genome.


Science ◽  
1972 ◽  
Vol 176 (4042) ◽  
pp. 1429-1431 ◽  
Author(s):  
F. Ruddle ◽  
F. Ricciuti ◽  
F. A. McMorris ◽  
J. Tischfield ◽  
R. Creagan ◽  
...  

1986 ◽  
Vol 12 (1) ◽  
pp. 33-40 ◽  
Author(s):  
Wolfgang J. Rettig ◽  
Nicholas C. Dracopoli ◽  
Barbara A. Spengler ◽  
John H. Kersey ◽  
June L. Biedler ◽  
...  

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