Effect of Histamine on Basal and TRH/LH-RH-Stimulated PRL and LH Secretion during Different Phases of the Menstrual Cycle in Normal Women

1985 ◽  
Vol 41 (4) ◽  
pp. 337-341 ◽  
Author(s):  
Ulrich Knigge ◽  
Benedikte Thuesen ◽  
Flemming Wollesen ◽  
Birgit Svenstrup ◽  
Poul M. Christiansen
Keyword(s):  
Menstrual Cycle ◽  
Normal Women ◽  
Lh Rh ◽  
Lh Secretion

scholarly journals The Correlation between Hormonal Disturbance in PCOS Women and Serum Level of Kisspeptin

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Razaw O. Ibrahim ◽  
Shirwan H. Omer ◽  
Chro N. Fattah
Keyword(s):  
Menstrual Cycle ◽  
Polycystic Ovary ◽  
Essential Element ◽  
Free Testosterone ◽  
Serum Levels ◽  
Normal Weight ◽  
Normal Women ◽  
And Control ◽  
Lh Secretion ◽  
Ovarian Syndrome

Background. Kisspeptin is a neuropeptide that upregulates gonadotropin-releasing hormone (GnRH) secretion. It is an essential element for the luteinizing hormone (LH) surge and ovulation. Women with polycystic ovary syndrome (PCOS) expose alteration in both GnRH and LH secretion levels. Objective. This paper aims to evaluate serum kisspeptin levels in healthy and polycystic ovarian syndrome women. Furthermore, it investigates the effect of obesity and age on circulating kisspeptin levels in both normal and PCOS women. Moreover, it points out the correlation between kisspeptin and other hormonal parameters. Methods and Patients. One hundred women (60 are with PCOS and 40 are normal) were enrolled in the study. Five milliliter samples of blood from all the patients and control women were obtained twice during the menstrual cycle. All the study samples were classified depending on the age factor for several subgroups. Results. Kisspeptin levels were higher in PCOS patients than those in the normal group. Kisspeptin correlated with serum free testosterone level (r=0.26). In healthy women, preovulatory kisspeptin levels were higher than follicular kisspeptin levels (P<0.05), while this difference was insignificant in PCOS patients. The variation in serum kisspeptin levels between overweight/obese and normal-weight women was insignificant. In normal women, serum kisspeptin levels were higher in women >35 years than those <24 years at (P=0.03). Conclusion. The serum kisspeptin level is higher in PCOS women. Its levels fluctuate during the menstrual cycle, but these fluctuations are disturbed in PCOS women. The effect of BMI on serum kisspeptin levels is insignificant, and kisspeptin serum levels increase with age.

Alterations of the hypothalamic GnRH interpulse interval sequence over the normal menstrual cycle

1988 ◽  
Vol 255 (5) ◽  
pp. E696-E701 ◽  
Author(s):  
N. Santoro ◽  
J. P. Butler ◽  
M. Filicori ◽  
W. F. Crowley
Keyword(s):  
Menstrual Cycle ◽  
Renewal Process ◽  
Gnrh Secretion ◽  
Late Luteal Phase ◽  
Normal Menstrual Cycle ◽  
Lh Release ◽  
Interval Sequence ◽  
Normal Women ◽  
Normal Men ◽  
Lh Secretion

Luteinizing hormone (LH) is released in a pulsatile fashion from the anterior pituitary in response to hypothalamic gonadotropin-releasing hormone (GnRH) secretion. Previous autocorrelation analysis of the sequence of interpulse intervals of LH secretion in normal men has supported the hypothesis that the underlying hypothalamic mechanism of GnRH secretion governing episodic LH release is a renewal process, indicating that hypothalamic "memory," if present, does not extend back further in time than the preceding secretory pulse. A similar analysis of pulsatile LH secretion was undertaken in 45 studies of normal women, obtained throughout the menstrual cycle. Analysis of these studies revealed a process consistent with renewal throughout the follicular and early luteal phases. However, this relationship appears to break down in the mid-to-late luteal phase, indicating that alternative feedback pathways provide an overriding influence on the underlying renewal process of hypothalamic GnRH secretion. Pulsatile progesterone secretion by the corpus luteum, which first emerges at this stage of the menstrual cycle, may be the agent responsible for this feedback.

Lysine-Vasopressin Does Not Affect Basal and LH-RH-Stimulated LH and FSH Release during the Menstrual Cycle of Normal Women

1987 ◽  
Vol 24 (1) ◽  
pp. 56-61 ◽  
Author(s):  
P. Chiodera ◽  
R. Volpi ◽  
C. Cigarini ◽  
A. Caiazza ◽  
C. Marchesi ◽  
...  
Keyword(s):  
Menstrual Cycle ◽  
Lysine Vasopressin ◽  
Normal Women ◽  
Lh Rh

EFFECT OF LH-RH ON SERUM FSH, LH AND PROGESTERONE DURING THE LUTEAL PHASE OF THE MENSTRUAL CYCLE

1975 ◽  
Vol 80 (1_Suppla) ◽  
pp. S20
Author(s):  
I. Gerhard ◽  
M. Röhrich ◽  
K. Klinga ◽  
B. Runnebaum
Keyword(s):  
Menstrual Cycle ◽  
Luteal Phase ◽  
Lh Rh

Urinary melatonin, LH, oestradiol, progesterone excretion during the menstrual cycle or in women taking oral contraceptives

1987 ◽  
Vol 116 (1) ◽  
pp. 145-149 ◽  
Author(s):  
Jocelyne Brun ◽  
Bruno Claustrat ◽  
Michel David
Keyword(s):  
Oral Contraceptive ◽  
Menstrual Cycle ◽  
Urinary Excretion ◽  
Oral Contraceptives ◽  
Coefficient Of Variation ◽  
Luteal Phase ◽  
Positive Relationship ◽  
Follicular Phase ◽  
The Other ◽  
Normal Women

Abstract. Nocturnal urinary excretion of melatonin, LH, progesterone and oestradiol was measured by radioimmunoassay in nine normal women during a complete cycle. In addition, these hormonal excretions were studied in two women taking an oral contraceptive. A high within-subject coefficient of variation was observed for melatonin excretion in the two groups. In the nine normal cycling women, melatonin excretion was not decreased at the time of ovulation, but was significantly increased during the luteal phase compared with that of the follicular phase (P < 0.01). These data are consistent with a positive relationship between melatonin and progesterone during the luteal phase. In the two women under an oral contraceptive, melatonin excretion was found within the same range as for the other nine. The results are discussed in terms of pineal investigation in human.

Renal sodium retention does not occur during the luteal phase of the menstrual cycle in normal women

1992 ◽  
Vol 99 (3) ◽  
pp. 247-252 ◽  
Author(s):  
D. L. BISSON ◽  
G. D. DUNSTER ◽  
J. P. O'HARE ◽  
D. HAMPTON ◽  
M. D. PENNEY
Keyword(s):  
Menstrual Cycle ◽  
Luteal Phase ◽  
Sodium Retention ◽  
Normal Women

OVARIAN SECRETION RATES OF OESTROGENS, ANDROGENS AND PROGESTERONE IN NORMAL WOMEN AND IN WOMEN WITH PERSISTENT OVARIAN FOLLICLES

1974 ◽  
Vol 77 (3) ◽  
pp. 575-587 ◽  
Author(s):  
F. H. de Jong ◽  
D. T. Baird ◽  
H. J. van der Molen
Keyword(s):  
Menstrual Cycle ◽  
Production Rate ◽  
Follicular Fluid ◽  
Ovarian Follicles ◽  
Dehydroepiandrosterone Sulphate ◽  
Peripheral Plasma ◽  
Normal Women ◽  
Quantitative Contribution ◽  
Secretion Rates ◽  
Venous Plasma

ABSTRACT The concentrations of oestradiol-17β, oestrone, androstenedione, testosterone, dehydroepiandrosterone, dehydroepiandrosterone sulphate and progesterone were measured in ovarian venous plasma from one or both ovaries in 4 normal women during different stages of the menstrual cycle and in 4 women with persistent ovarian follicles. In addition the steroid concentrations in peripheral plasma and follicular fluid were estimated. All steroids mentioned, with the exception of dehydroepiandrosterone sulphate, were secreted by the ovaries. The concentrations of oestradiol-17β, oestrone, androstenedione and progesterone were higher in the venous plasma from the ovary containing the developing follicle or corpus luteum than in venous plasma from the contralateral ovary. There was a good correlation between ovarian secretion of the oestrogenic steroids and androstenedione. Finally, the quantitative contribution of the ovarian secretion to the blood production rates of the androgens and progesterone was calculated. The only contributions exceeding 20 % of the blood production rate were those of progesterone and androstenedione during the second half of the cycle.

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