Effects of Injections and/or Chronic Implants of Melatonin and 5-Methoxytryptamine on Plasma Thyroid Hormones in Male and Female Syrian Hamsters

1984 ◽  
Vol 39 (4) ◽  
pp. 361-366 ◽  
Author(s):  
Mary K. Vaughan ◽  
Bruce A. Richardson ◽  
Larry J. Petterborg ◽  
Anke P. Holtorf ◽  
George M. Vaughan ◽  
...  
1984 ◽  
Vol 20 (6) ◽  
pp. 1471
Author(s):  
M.K. Vaughan ◽  
B.A. Richardson ◽  
L.J. Petterborg ◽  
G.M. Vaughan ◽  
R.J. Reiter

1984 ◽  
Vol 5 (5) ◽  
pp. 413-418 ◽  
Author(s):  
MARY K. VAUGHAN ◽  
BRUCE A. RICHARDCON ◽  
LARRY J. PETTERBORG ◽  
GEORGE M. VAUGHAN ◽  
RUSSEL J. REITER

1999 ◽  
Vol 43 (1) ◽  
pp. 47-51 ◽  
Author(s):  
E. Turley ◽  
N.C. Armstrong ◽  
J.M.W. Wallace ◽  
W.S. Gilmore ◽  
V.J. McKelvey-Martin ◽  
...  

2003 ◽  
Vol 44 (3) ◽  
pp. 293-299 ◽  
Author(s):  
Kim L Huhman ◽  
Matia B Solomon ◽  
Marcus Janicki ◽  
Alvin C Harmon ◽  
Stacie M Lin ◽  
...  

2017 ◽  
Vol 177 ◽  
pp. 264-269 ◽  
Author(s):  
Amy P. Ross ◽  
Alisa Norvelle ◽  
Dennis C. Choi ◽  
James C. Walton ◽  
H. Elliott Albers ◽  
...  

1991 ◽  
Vol 69 (4) ◽  
pp. 1004-1009 ◽  
Author(s):  
J. Vriend

Gonadal involution, with reduced serum levels of luteinizing hormone and prolactin, was induced in male Syrian hamsters by daily injections of melatonin, given in the evening. Highly significant increases in daytime concentrations of 5-hydroxyindoleacetic acid (5-HIAA) and in the ratio of 5-HIAA to serotonin (5-HT) were noted in extracts of mediobasal hypothalamus of melatonin-treated hamsters. An increase in the 5-HIAA/5-HT ratio, with decreased 5-HT concentrations, was found in brainstem extracts of hamsters treated with melatonin. The increase in the 5-HIAA/5-HT ratio was not prevented by inhibition of catecholamine synthesis with α-methyl-p-tyrosine, which suggests that the melatonin-induced increase in the 5-HIAA/5-HT ratio was not due to changes in catecholamine turnover. These results are consistent with the view that serotonergic neurons terminating in the hypothalamus mediate the melatonin-induced inhibition of luteinizing hormone, prolactin, and thyroid hormones accompanying gonadal involution.


2000 ◽  
Vol 46 (5) ◽  
pp. 35-39
Author(s):  
L. I. Nadolnik ◽  
N. V. Emelyanov ◽  
I. P. Pasteur ◽  
V. V. Vinogradov

Main parameters of complex formation of corticosteroid-binding globulin (CSG) were studied in young male and female rats with hypothyrosis induced by mercasolyl in a daily dose of 6 and 30 mg/kg. No pronounced differences in CSG, typical of adult animals, were observed in young rats under conditions of thyroid function inhibition. Steroidand androgen-inhibitory and estrogen-inducing effects of hormones towards CSG did not manifest in hypothyrosis. Decrease in the level of thyroid hormones is characterized by increased affinity of CSG for glucocorticoids and a decrease in the concentration of binding sites. These data indicate that thyroid hormones are the primary regulators of CSG activity. Possibility of modifying CSG affinity and role of this factor in regulation of biological activity of glucocorticoids are discussed.


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