A Striking Diurnal Variation in Plasma Testosterone Concentrations in Infantile Male Rhesus Monkeys (Macaca mulatta)

1982 ◽  
Vol 35 (5) ◽  
pp. 370-373 ◽  
Author(s):  
Tony M. Plant
1978 ◽  
Vol 76 (1) ◽  
pp. 67-74 ◽  
Author(s):  
R. M. ROSE ◽  
T. P. GORDON ◽  
I. S. BERNSTEIN

SUMMARY Concentrations of cortisol and testosterone in the plasma of adult male rhesus monkeys living in social groups were determined during a 27-h period. Capture and venipuncture of experienced, conditioned animals did not lead to a fall in the concentration of testosterone in the plasma during the 90 min immediately after removal from the group. Both plasma cortisol and plasma testosterone concentrations showed a significant fall and rise in samples collected every 3 h during a 27-h period, even though there was considerable individual variation. During the autumn breeding season, animals showed higher concentrations of testosterone at both 10.00 and 22.00 h compared with those observed at the same times during the summer. Even though animals demonstrated significant diurnal changes, testosterone samples withdrawn at the same time of day (10.00 h) on consecutive days were significantly correlated with one another (r = 0·65, n = 27, P < 0·01), suggesting the usefulness of sampling once a day to study potential environmental influences on plasma testosterone concentrations.


The work of Collings (1926), Allen (1927, 1928), Morrell (1930), and Parkes and Zuckerman (1931) on rhesus monkeys has established the fact that the brilliant coloration of the skin about the genitalia and the face, loosely referred to as the sex skin, and seen in both the female and male of this species, can be called forth by the administration of œstrous-producing hormone. Parkes and Zuckerman could not produce it in the case of one castrate male rhesus and a castrate female bonnet monkey. M. radiata , but they obtained in an ovariectomized baboon the full swelling seen during the follicular phase, and Dohrn, Hohlweg and Schoeller (1932, 1933) working with both male and female baboons and employing crystalline “ progynon,” were uniformly successful in eliciting a reaction, which in the male specimens of this species consisted of a remarkable œdema of the genitalia. In the present paper we should like to report our own experiments concerning this particular skin reaction to œstriol. Material and Technique Eight macaques, including one immature and four adolescent animals, were studied. Of the total, five were normal animals, four of these being males. The remaining three comprised one castrate male and two hypophysectomized-castrate females.


Nature ◽  
1971 ◽  
Vol 231 (5302) ◽  
pp. 366-368 ◽  
Author(s):  
ROBERT M. ROSE ◽  
JOHN W. HOLADAY ◽  
IRWIN S. BERNSTEIN

2015 ◽  
Vol 78 (1) ◽  
pp. 152-166 ◽  
Author(s):  
Matthew J. Kessler ◽  
Qian Wang ◽  
Antonietta M. Cerroni ◽  
Marc D. Grynpas ◽  
Olga D. Gonzalez Velez ◽  
...  

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