Association of the Homeobox Transcription Factor Gene ENGRAILED 2 with Autistic Disorder in Chinese Children

2008 ◽  
Vol 57 (1-2) ◽  
pp. 3-8 ◽  
Author(s):  
Pinchen Yang ◽  
For-Wey Lung ◽  
Yuh-Jyh Jong ◽  
Hsin-Yi Hsieh ◽  
Chung-Ling Liang ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Autistic Disorder ◽  
Chinese Children ◽  
Transcription Factor Gene ◽  
Factor Gene ◽  
Homeobox Transcription Factor

Cloning and characterization of a novel bicoid-related homeobox transcription factor gene, RIEG, involved in Rieger syndrome

1996 ◽  
Vol 14 (4) ◽  
pp. 392-399 ◽  
Author(s):  
Elena V. Semina ◽  
Rebecca Reiter ◽  
Nancy J. Leysens ◽  
W. Lee M. Alward ◽  
Kent W. Small ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Transcription Factor Gene ◽  
Factor Gene ◽  
Rieger Syndrome ◽  
Homeobox Transcription Factor

scholarly journals Downregulation ofHlxClosely Related to the Decreased Expressions ofT-betandRunx3in Patients with Gastric Cancer May Be Associated with a Pathological Event Leading to the Imbalance of Th1/Th2

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Yan Xu ◽  
Jingjing Gao ◽  
Zhaoliang Su ◽  
Xiaoli Dai ◽  
Yazhen Li ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Transcription Factor ◽  
Associated Factors ◽  
Mrna Level ◽  
Tumor Development ◽  
Transcription Factor Gene ◽  
Factor Gene ◽  
Homeobox Transcription Factor ◽  
Pathological Event ◽  
Development Of Gastric Cancer

T-betplays an important role in immunoregulation; it induces the differentiation of Th1 together with the homeobox transcription factor geneHlx. Recent studies show thatT-betand Th1-associated factors are critical in regulating tumor development. However, the contributions ofHlxin the occurrence and development of cancer remain unknown. In this study, theHlx,T-bet,Runx3, and IFN-γwere measured in PBMC from patients with gastric cancer and the correlation betweenHlxandT-betor IFN-γwas assessed. The expression levels ofHlx,T-bet, andIFN-γwere significantly decreased, and there was a positive correlation betweenHlxandT-betor IFN-γ. In addition, theRunx3expression was also downregulated with the lowerT-betmRNA level. These results suggested that the decreasedHlxexpression was closely associated withT-betandRunx3downregulations and may contribute to the development of gastric cancer.

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