Use of Buspirone in Patients with Generalized Anxiety Disorder and Coexisting Depressive Symptoms

1992 ◽  
Vol 25 (4) ◽  
pp. 193-201 ◽  
Author(s):  
R.E. Gammans ◽  
J.C. Stringfellow ◽  
A.J. Hvizdos ◽  
R.J. Seidehamel ◽  
J.B. Cohn ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Generalized Anxiety

P.3.036 Pregabalin in the treatment of core depressive symptoms in generalized anxiety disorder

2004 ◽  
Vol 14 ◽  
pp. S319
Author(s):  
A. Khan ◽  
S.A. Montgomery ◽  
N. Simon ◽  
G. Farfel ◽  
K. Tobias ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Generalized Anxiety

scholarly journals The Role of Ethnicity in Expression, Prevalence, and Severity of Generalized Anxiety Disorder and their Overlap with Depressive Symptoms: Epidemiological Evidence from a Rapidly Developing Middle Eastern Country

2021 ◽  
Author(s):  
Salma M. Khaled ◽  
Monica Zolezzi
Keyword(s):  
Depressive Symptoms ◽  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Middle Eastern ◽  
Depression Symptoms ◽  
Generalized Anxiety ◽  
Middle Eastern Country ◽  
Eastern Country ◽  
Symptom Profile ◽  
The Impact

Abstract IntroductionQatar is a small but high-income Middle Eastern country with a large influx of migrants each year. However, the impact of changing population structure and urbanization on prevalence of generalized anxiety symptoms remains unexplored to date. Materials & MethodsA total of 2,640 participants interviewed by phone using the Generalized Anxiety Disorder (GAD-7) and the Patient Health Questionnaire (PHQ-2). Bivariate and multinomial logistic regression analyses were conducted to explore the associations of ethnicity (Arab versus Non-Arab) with severity and symptom profile of GAD and overlap with depressive symptoms. ResultsThe point prevalence of mild, moderate, and severe symptoms were 13.4% (95% CI: 11.9 – 15.0), 2.7% (95% CI: 2.0 – 3.5), and 0.9% (95% CI: 0.6– 1.4), respectively. Arab ethnicity was associated with mild GAD (OR=1.78, p=0.009) and moderate-to-severe GAD (OR=2.36, p=0.044). Relative to non-migrants, migrant types were not significantly associated with mild or with moderate-to- severe GAD. Interactions between depressive symptoms and ethnicity were evident and statistically significant for the association with mild GAD versus no GAD (OR=0.34, p=0.003). ConclusionsEthnicity moderated the association of depression symptoms and GAD severity, with potential implications for early screening and community intervention.

Abstract TMP42: Younger Age and Depressive Symptoms Predict Post-Stroke Generalized Anxiety Disorder

Stroke ◽  
2019 ◽  
Vol 50 (Suppl_1) ◽  
Author(s):  
Arunima Kapoor ◽  
Kevin Si ◽  
Nathan Herrmann ◽  
Krista L Lanctôt ◽  
Brian J Murray ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Generalized Anxiety ◽  
Post Stroke ◽  
Younger Age

Mental health impact of COVID-19 pandemic among physicians, nurses, and other healthcare providers, in the province of Alberta (Preprint)

2021 ◽  
Author(s):  
Hany ElGindi ◽  
Reham Shalaby ◽  
April Gusnowski ◽  
Wesley Vuong ◽  
Shireen Surood ◽  
...  
Keyword(s):  
Mental Health ◽  
Depressive Symptoms ◽  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
High Stress ◽  
Well Being ◽  
Self Report ◽  
Generalized Anxiety ◽  
Cross Sectional Survey ◽  
Cross Sectional

BACKGROUND During the COVID-19 pandemic, threats to mental health, psychological safety, and well-being are evident, particularly among the first responders and the healthcare staff. OBJECTIVE This study aimed to examine the prevalence and the potential predictors of the likely stress, generalized anxiety disorder, and major depressive disorder among healthcare workers (HCW). METHODS A cross-sectional survey was used through a survey link sent to gather demographic information and responses on several self-report scales, including the Perceived Stress Scale (PSS), Generalized Anxiety Disorder 7-item (GAD-7) scale, and Patient Health Questionnaire-9 (PHQ-9) among the various HCW groupings who subscribed to the Text4Hope program. RESULTS This study revealed that the HCW expressed an estimated high prevalence of moderate/high stress rates 840 (81.2%), while the likelihood of moderate/severe anxiety and depressive symptoms were 369 (38.6%), and 317 (32.7%), respectively, during COVID-19 pandemic. Nurses and other HCW were significantly more likely to report depressive symptoms, compared to physicians, (F (2, 159.47) =15.89, 95% CI= (-5.05) -(-2.04). Younger age groups of HCW (≤30 y) were more prone to report likely stress, anxiety, and depressive symptoms, compared to HCW 41-50y and >50y (Odd’s ratio range: 1.82- 3.03). Similarly, females and those who reported a lack of social support (separated/divorced and single) among HCW, had a higher likelihood to report likely stress and depressive symptoms, respectively (OR=1.8 and 1.6). CONCLUSIONS This cross-sectional study revealed the significant impact of COVID-19 pandemic on mental health and indicated significant vulnerability among groups of HCW in Alberta. CLINICALTRIAL Ethical approval for this research was obtained through the University of Alberta Health Research Ethics Board (Pro00086163).

scholarly journals Exploring the Association Between Physical Activity and Risk of Mental Health Disorders in Saudi Arabian Adults: Cross-sectional Study (Preprint)

2020 ◽  
Author(s):  
Nora A Althumiri ◽  
Mada H Basyouni ◽  
Nasser F BinDhim
Keyword(s):  
Mental Health ◽  
Physical Activity ◽  
Depressive Symptoms ◽  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Anxiety Symptoms ◽  
World Health ◽  
Moderate Intensity ◽  
Generalized Anxiety ◽  
Cross Sectional

BACKGROUND The relationship between physical activity and mental health, especially the symptoms of major depressive disorder (MDD) and generalized anxiety disorder (GAD), has received increasing attention in recent years. OBJECTIVE The aim of this study was to explore the association between fulfilling the World Health Organization (WHO) global recommendations on physical activity and the risk and symptoms of MDD and GAD in the Saudi population. METHODS This study was a secondary analysis of data from a large nationwide cross-sectional survey conducted via phone interviews in June and July 2020. In this study, a proportional quota sampling technique was used to obtain an equal distribution of participants, stratified by age and gender, across the 13 regions of Saudi Arabia. The main mental health screening tool used for the risk of MDD was the Patient Health Questionnaire-9 (PHQ-9). Risk of GAD was measured using the Generalized Anxiety Disorder-7 (GAD-7) scale. Participants self-reported whether they fulfill the WHO global recommendations on (1) moderate-intensity aerobic physical activity (MIPA) and (2) vigorous-intensity aerobic physical activity (VIPA). The results were then analyzed based on the following two categories: fulfilling the WHO global recommendations or not. RESULTS The data analysis included 8333 participants recruited in the main study between June and July 2020. The response rate was 81.45% (8333/10,231). Of them, 50.3% (4192/8333) were female, and the mean age was 36.5 years, with a median age of 36 years and a range from 18 to 90 years. The average total PHQ-9 score was 5.61, and the average total GAD-7 score was 4.18. For men, the average total PHQ-9 and GAD-7 scores were associated with fulfilling recommendations for MIPA; however, there were no associations for VIPA in both sexes. Fulfilling the WHO’s recommendations for MIPA was associated with considerably fewer depressive symptoms in six of the nine items in the PHQ-9. Moreover, fulfilling recommendations for MIPA was associated with considerably fewer anxiety symptoms in six of the seven items in the GAD-7. However, fulfilling recommendations for VIPA was significantly associated with more depressive symptoms in one of the PHQ-9 items (“Thoughts that you would be better off dead or thoughts of hurting yourself in some way;” <i>P</i>&lt;.001). CONCLUSIONS This study has shown that fulfilling guidelines on MIPA is associated with less overall risk of MDD and GAD in males and fewer depressive and anxiety symptoms generally in a nonclinical population. In the general population, an increase in MIPA may improve well-being and general mental health.

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