Oxidized Low-Density Lipoprotein Biomarkers in Patients with End-Stage Renal Failure: Acute Effects of Hemodialysis

2007 ◽  
Vol 25 (5-6) ◽  
pp. 457-465 ◽  
Author(s):  
Maurizio Bossola ◽  
Luigi Tazza ◽  
Esther Merki ◽  
Stefania Giungi ◽  
Giovanna Luciani ◽  
...  
Keyword(s):  
Renal Failure ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Low Density ◽  
Acute Effects ◽  
Oxidized Low Density Lipoprotein ◽  
End Stage Renal Failure ◽  
End Stage

Effects of hemodialysis and vitamin E supplementation on low-density lipoprotein oxidizability in end-stage renal failure

2012 ◽  
Vol 26 (3) ◽  
pp. 549-555 ◽  
Author(s):  
Simona Baldi ◽  
Maurizio Innocenti ◽  
Silvia Frascerra ◽  
Monica Nannipieri ◽  
Alberto Lippi ◽  
...  
Keyword(s):  
Renal Failure ◽  
Vitamin E ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Low Density ◽  
End Stage Renal Failure ◽  
End Stage ◽  
Vitamin E Supplementation

Acute effects of oxidized low density lipoprotein on metabolic responses in macrophages

1998 ◽  
Vol 12 (1) ◽  
pp. 111-118 ◽  
Author(s):  
Helga E. De Vries ◽  
Eric Ronken ◽  
Jan-hendrik Reinders ◽  
Bas Buchner ◽  
Theo J. C. van berkel ◽  
...  
Keyword(s):  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Metabolic Responses ◽  
Low Density ◽  
Acute Effects ◽  
Oxidized Low Density Lipoprotein

scholarly journals Antibody to oxidized low-density lipoprotein and cardiovascular mortality in end-stage renal disease

2002 ◽  
Vol 62 (6) ◽  
pp. 2230-2237 ◽  
Author(s):  
Tetsuo Shoji ◽  
Mariko Fukumoto ◽  
Eiji Kimoto ◽  
Kayo Shinohara ◽  
Masanori Emoto ◽  
...  
Keyword(s):  
Renal Disease ◽  
Cardiovascular Mortality ◽  
End Stage Renal Disease ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Low Density ◽  
Oxidized Low Density Lipoprotein ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Acute effects of oxidized low density lipoprotein on metabolic responses in macrophages

1998 ◽  
Vol 12 (1) ◽  
pp. 111-118
Author(s):  
Helga E. Vries ◽  
Eric Ronken ◽  
Jan‐Hendrik Reinders ◽  
Bas Buchner ◽  
Theo J. C. Van Berkel ◽  
...  
Keyword(s):  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Metabolic Responses ◽  
Low Density ◽  
Acute Effects ◽  
Oxidized Low Density Lipoprotein

scholarly journals Oxidized Low-Density Lipoprotein Serum Concentrations and Cardiovascular Morbidity in End Stage of Renal Disease

2018 ◽  
Vol 5 (3) ◽  
pp. 35 ◽  
Author(s):  
Vaia Raikou ◽  
Vasilios Kardalinos ◽  
Despina Kyriaki
Keyword(s):  
Vitamin D ◽  
Renal Disease ◽  
Cardiac Dysfunction ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Cardiovascular Morbidity ◽  
Low Density ◽  
Serum Concentrations ◽  
Oxidized Low Density Lipoprotein ◽  
End Stage

Introduction: Oxidized low-density lipoprotein (ox-LDL) is considered a main biomarker of oxidative stress, a common characteristic in end stage renal disease. We examined the relationship between ox-LDL serum concentrations and cardiovascular disease in permanent hemodiafiltration therapy patients. Methods: Ox-LDL values were measured by ELISA and were corrected for LDL-cholesterol (LDL-C) in 96 participants and in 45 healthy control subjects. We performed chi-square tests and adjusted models for the role of ox-LDL on cardiovascular morbidity including coronary artery disease, left ventricular hypertrophy, systolic, diastolic dysfunction and peripheral arterial disease. Results: ox-LDL/LDL-C values were significantly higher in patients than in control group (p = 0.02), due to increased ox-LDL serum levels rather than to low LDL-C. The unadjusted relationship between high ox-LDL/LDL-C and low ejection fraction was found significant (x2 = 9.04, p = 0.003), although the association with the other cardiovascular manifestations was found non-significant. In the adjusted model for the prediction of systolic cardiac dysfunction, high ox-LDL/LDL-C, old age and non-administration of vitamin D supplementation during dialysis session were found to be significant predictors after adjustment to the confounder. Moreover, the association between systolic cardiac dysfunction and non-administration of vitamin D derivatives during dialysis sessions was found significant (x2 = 6.9, p = 0.008). Conclusions: This study showed a significant association between high ox-LDL and systolic cardiac dysfunction in permanent hemodiafiltration therapy patients. This relationship seems to be influenced by aging and pharmaceutical therapy during dialysis sessions, including vitamin D derivatives.

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