Three-Dimensional High-Resolution Diffusion Tensor Imaging and Tractography of the Developing Rabbit Brain

2008 ◽  
Vol 30 (4) ◽  
pp. 262-275 ◽  
Author(s):  
Helen D’Arceuil ◽  
Christina Liu ◽  
Pat Levitt ◽  
Barbara Thompson ◽  
Barry Kosofsky ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
High Resolution ◽  
Diffusion Tensor ◽  
Three Dimensional ◽  
Rabbit Brain

scholarly journals 4.7-T diffusion tensor imaging of acute traumatic peripheral nerve injury

2015 ◽  
Vol 39 (3) ◽  
pp. E9 ◽  
Author(s):  
Richard B. Boyer ◽  
Nathaniel D. Kelm ◽  
D. Colton Riley ◽  
Kevin W. Sexton ◽  
Alonda C. Pollins ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
High Resolution ◽  
Peripheral Nerve ◽  
Nerve Injury ◽  
Peripheral Nerve Injury ◽  
Diffusion Tensor ◽  
Ex Vivo ◽  
Nerve Fibers ◽  
Nerve Transection ◽  
Nerve Injuries

Diagnosis and management of peripheral nerve injury is complicated by the inability to assess microstructural features of injured nerve fibers via clinical examination and electrophysiology. Diffusion tensor imaging (DTI) has been shown to accurately detect nerve injury and regeneration in crush models of peripheral nerve injury, but no prior studies have been conducted on nerve transection, a surgical emergency that can lead to permanent weakness or paralysis. Acute sciatic nerve injuries were performed microsurgically to produce multiple grades of nerve transection in rats that were harvested 1 hour after surgery. High-resolution diffusion tensor images from ex vivo sciatic nerves were obtained using diffusion-weighted spin-echo acquisitions at 4.7 T. Fractional anisotropy was significantly reduced at the injury sites of transected rats compared with sham rats. Additionally, minor eigenvalues and radial diffusivity were profoundly elevated at all injury sites and were negatively correlated to the degree of injury. Diffusion tensor tractography showed discontinuities at all injury sites and significantly reduced continuous tract counts. These findings demonstrate that high-resolution DTI is a promising tool for acute diagnosis and grading of traumatic peripheral nerve injuries.

scholarly journals Preliminary Experience with Visualization of Intracortical Fibers by Focused High-Resolution Diffusion Tensor Imaging

2007 ◽  
Vol 29 (1) ◽  
pp. 146-150 ◽  
Author(s):  
T. Jaermann ◽  
N. De Zanche ◽  
P. Staempfli ◽  
K.P. Pruessmann ◽  
A. Valavanis ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
High Resolution ◽  
Diffusion Tensor

scholarly journals In vivo high-resolution diffusion tensor imaging of the developing neonatal rat cortex and its relationship to glial and dendritic maturation

2019 ◽  
Vol 224 (5) ◽  
pp. 1815-1829 ◽  
Author(s):  
Markus Breu ◽  
Dominik Reisinger ◽  
Liangcheng Tao ◽  
Dan Wu ◽  
Yajing Zhang ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
High Resolution ◽  
Diffusion Tensor ◽  
Neonatal Rat ◽  
Rat Cortex

scholarly journals Feasibility of creating a high-resolution 3D diffusion tensor imaging based atlas of the human brainstem: A case study at 11.7T

NeuroImage ◽  
2013 ◽  
Vol 74 ◽  
pp. 117-127 ◽  
Author(s):  
Manisha Aggarwal ◽  
Jiangyang Zhang ◽  
Olga Pletnikova ◽  
Barbara Crain ◽  
Juan Troncoso ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
High Resolution ◽  
Diffusion Tensor

Progressive brain changes in schizophrenia: a 1-year follow-up study of diffusion tensor imaging

2009 ◽  
Vol 21 (6) ◽  
pp. 301-307 ◽  
Author(s):  
Miho Ota ◽  
Satoko Obu ◽  
Noriko Sato ◽  
Katsuyoshi Mizukami ◽  
Takashi Asada
Keyword(s):  
Diffusion Tensor Imaging ◽  
Diffusion Tensor ◽  
Three Dimensional ◽  
Anterior Cingulate ◽  
Volume Data ◽  
Cross Sectional ◽  
Schizophrenic Patients ◽  
Brain Changes ◽  
Magnetic Resonance Imaging Mri

Objective:Recent cross-sectional studies suggest that brain changes in schizophrenia are progressive during the course of the disorder. However, it remains unknown whether this is a global process or whether some brain areas are affected to a greater degree. The aim of this study was to examine the longitudinal brain changes in patients with chronic older schizophrenia by magnetic resonance imaging (MRI).Methods:Three-dimensional (3D) T1-weighted and diffusion tensor (DT) MRI were performed twice on each of 16 chronic older schizophrenia patients (mean age = 58.1 ± 6.7 years ) with an interval of 1 year between imaging sessions. To clarify the longitudinal morphological and white matter changes, volume data and normalised diffusion tensor imaging (DTI) metrics were compared between the first and follow-up studies using a paired t-test.Results:Focal cortical volume loss was observed in the left prefrontal lobe and anterior cingulate on volumetric study. In addition, DTI metrics changed significantly at the bilateral posterior superior temporal lobes, left insula, genu of the corpus callosum and anterior cingulate.Conclusion:There are ongoing changes in the brains of schizophrenic patients during the course of the illness. Discrepancies between volume data and DTI metrics may indicate that the pattern of progressive brain changes varies according to brain region.

High-resolution diffusion tensor imaging using interleaved echo-planar imaging

2000 ◽  
Author(s):  
Roland Bammer ◽  
Manfred J. Augustin ◽  
Thomas Seifert ◽  
S. Strasser-Fuchs ◽  
Rudolf Stollberger ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
High Resolution ◽  
Diffusion Tensor ◽  
Echo Planar Imaging ◽  
Planar Imaging ◽  
Echo Planar
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