Neuropsychiatric Symptoms in Nursing Home Patients: Factor Structure Invariance of the Dutch Nursing Home Version of the Neuropsychiatric Inventory in Different Stages of Dementia

2007 ◽  
Vol 24 (3) ◽  
pp. 169-176 ◽  
Author(s):  
Sytse U. Zuidema ◽  
Jos F.M. de Jonghe ◽  
Frans R.J. Verhey ◽  
Raymond T.C.M. Koopmans
Keyword(s):  
Nursing Home ◽  
Factor Structure ◽  
Neuropsychiatric Symptoms ◽  
Neuropsychiatric Inventory ◽  
Nursing Home Patients

Stability of the factor structure of the Neuropsychiatric Inventory in a 31-month follow-up study of a large sample of nursing-home patients with dementia

2011 ◽  
Vol 24 (1) ◽  
pp. 62-73 ◽  
Author(s):  
Geir Selbæk ◽  
Knut Engedal
Keyword(s):  
Nursing Home ◽  
Factor Structure ◽  
Neuropsychiatric Symptoms ◽  
Neuropsychiatric Inventory ◽  
Large Sample ◽  
Nursing Home Patients ◽  
Affective Symptoms ◽  
The Stability ◽  
Over Time

ABSTRACTBackground: Neuropsychiatric symptoms (NPS) are highly prevalent among nursing home patients with dementia. Several studies have investigated subsyndromes of NPS but the stability of these subsyndromes over time has rarely been examined. We have examined the stability over time of the factor structure of the Neuropsychiatric Inventory-Nursing Home version (NPI-NH) in a large sample of nursing-home patients with dementia.Methods: Nursing-home patients with dementia were assessed with the NPI-NH at baseline (n = 895), and at 12-month (n = 592) and 31-month (n = 278) follow-up assessments, giving three partly overlapping samples. Exploratory factor analysis was done to investigate neuropsychiatric subsyndromes of the NPI-NH at each assessment in these samples.Results: Three- or four-factor solutions were found, termed agitation, psychosis, apathy, and affective symptoms. Depression and anxiety (affective), delusion and hallucination (psychosis), and agitation and irritability (agitation) were the symptoms that most often co-occurred in the same factor. Apathy did not load together with affective symptoms at any of the assessments.Conclusions: Subsyndromes of the NPI-NH are relatively stable over 31-month follow-up assessments in nursing-home patients with dementia, indicating that these subsyndromes may be useful for following the natural course of symptoms as well as observing the effect of interventions. Our findings lend support to the distinction between apathy and affective symptoms, which may have important clinical implications.

scholarly journals Natural course of neuropsychiatric symptoms in nursing home patients with mental-physical multimorbidity in the first eight months after admission

2018 ◽  
Vol 24 (1) ◽  
pp. 155-161
Author(s):  
Anne van den Brink ◽  
Debby L. Gerritsen ◽  
Miranda M.H. de Valk ◽  
Richard Oude Voshaar ◽  
Raymond Koopmans
Keyword(s):  
Nursing Home ◽  
Neuropsychiatric Symptoms ◽  
Natural Course ◽  
Nursing Home Patients

The course of neuropsychiatric symptoms in nursing-home patients with dementia over a 53-month follow-up period

2013 ◽  
Vol 26 (1) ◽  
pp. 81-91 ◽  
Author(s):  
Geir Selbæk ◽  
Knut Engedal ◽  
Jūratė Šaltytė Benth ◽  
Sverre Bergh
Keyword(s):  
Nursing Home ◽  
Rating Scale ◽  
Neuropsychiatric Symptoms ◽  
Clinical Dementia Rating ◽  
Severe Dementia ◽  
Persistent Symptoms ◽  
Nursing Home Patients ◽  
Affective Symptoms ◽  
Clinically Significant

ABSTRACTBackground:Neuropsychiatric symptoms (NPS) are prevalent in nursing-home (NH) patients with dementia, but little is known about the long-term course of these symptoms.Methods:In this study, 931 NH patients with dementia took part in a prospective cohort study with four assessments over a 53-month follow-up period. NPS and level of dementia were assessed with the Neuropsychiatric Inventory scale and the Clinical Dementia Rating scale, respectively.Results:Mild, moderate, and severe dementia was present in 25%, 33%, and 42%, respectively. There was an increase in the severity of the dementia from the first to the fourth assessment. Agitation, irritability, disinhibition, and apathy were the most prevalent and persistent symptoms during the study period. The affective subsyndrome (depression and anxiety) became less severe, whereas the agitation subsyndrome (agitation/aggression, disinhibition, and irritability) and apathy increased in severity during the follow-up period. More severe dementia was associated with more severe agitation, psychosis, and apathy, but not more severe affective symptoms. Mild dementia was associated with an increase in the severity of psychosis, whereas moderate or severe dementia was associated with decreasing severity of psychosis over the follow-up period.Conclusion:Nearly all the patients experienced clinically significant NPS, but individual symptoms fluctuated. Affective symptoms became less severe, while agitation and apathy increased in severity. An increase in dementia severity was associated with an increase in the severity of agitation, psychosis, and apathy, but not affective symptoms. The results may have implications when planning evaluation, treatment, and the prevention of NPS in NH patients.

Racial Differences in Neuropsychiatric Symptoms Among Dementia Patients: A Comparison of African Americans and Whites

2000 ◽  
Vol 12 (S1) ◽  
pp. 395-402 ◽  
Author(s):  
Carl I. Cohen
Keyword(s):  
African American ◽  
Nursing Home ◽  
African Americans ◽  
Racial Differences ◽  
Neuropsychiatric Symptoms ◽  
Psychotic Symptoms ◽  
Sociodemographic Variable ◽  
Behavioral Disturbances ◽  
Dementia Patients ◽  
Nursing Home Patients

Race is a critical sociodemographic variable that may serve as a marker for genetic, clinical, cultural, and socioeconomic factors. There have been several studies that found differences between African Americans and Whites in the neuropsychiatric symptoms of dementia. There have been fairly consistent findings that psychotic symptoms—hallucinations and delusions—are more prevalent among African American patients with dementia (Cohen & Carlin, 1993; Cooper et al., 1991, Deutsch et al., 1991; Fabrega et al., 1988), and that depression is higher among Whites than among African Americans (Fabrega et al., 1988; Walker et al., 1995). One study by Class and colleagues (1996) also suggested that behavioral disturbances might be higher among White than among African American nursing home patients, a majority of whom had dementia.

scholarly journals Prevalence and Correlates of Neuropsychiatric Symptoms in Nursing Home Patients With Young-Onset Dementia: The BEYOnD Study

2016 ◽  
Vol 17 (6) ◽  
pp. 495-500 ◽  
Author(s):  
Ans J.M.J. Mulders ◽  
Ilma W.F. Fick ◽  
Hans Bor ◽  
Frans R.J. Verhey ◽  
Sytse U. Zuidema ◽  
...  
Keyword(s):  
Nursing Home ◽  
Neuropsychiatric Symptoms ◽  
Young Onset ◽  
Nursing Home Patients ◽  
Young Onset Dementia
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