scholarly journals Prevalence and Correlates of Neuropsychiatric Symptoms in Nursing Home Patients With Young-Onset Dementia: The BEYOnD Study

2016 ◽  
Vol 17 (6) ◽  
pp. 495-500 ◽  
Author(s):  
Ans J.M.J. Mulders ◽  
Ilma W.F. Fick ◽  
Hans Bor ◽  
Frans R.J. Verhey ◽  
Sytse U. Zuidema ◽  
...  
Keyword(s):  
Nursing Home ◽  
Neuropsychiatric Symptoms ◽  
Young Onset ◽  
Nursing Home Patients ◽  
Young Onset Dementia

scholarly journals Prevalence and correlates of psychotropic drug use in Dutch nursing home patients with young‐onset dementia

2019 ◽  
Vol 34 (8) ◽  
pp. 1185-1193 ◽  
Author(s):  
Ans J.M.J. Mulders ◽  
Sytse U. Zuidema ◽  
Renée Leeuwis ◽  
Hans Bor ◽  
Frans R.J. Verhey ◽  
...  
Keyword(s):  
Nursing Home ◽  
Drug Use ◽  
Psychotropic Drug ◽  
Young Onset ◽  
Psychotropic Drug Use ◽  
Nursing Home Patients ◽  
Young Onset Dementia

scholarly journals Differences in neuropsychiatric symptoms between nursing home residents with young-onset dementia and late-onset dementia

2018 ◽  
Vol 23 (5) ◽  
pp. 581-586 ◽  
Author(s):  
Britt Appelhof ◽  
Christian Bakker ◽  
Jeannette C. L. Van Duinen-van Den IJssel ◽  
Sandra A. Zwijsen ◽  
Martin Smalbrugge ◽  
...  
Keyword(s):  
Nursing Home ◽  
Late Onset ◽  
Neuropsychiatric Symptoms ◽  
Nursing Home Residents ◽  
Young Onset ◽  
Young Onset Dementia ◽  
Late Onset Dementia

scholarly journals The Determinants of Quality of Life of Nursing Home Residents with Young-Onset Dementia and the Differences between Dementia Subtypes

2017 ◽  
Vol 43 (5-6) ◽  
pp. 320-329 ◽  
Author(s):  
Britt Appelhof ◽  
Christian Bakker ◽  
Jeannette C.L. Van Duinen-van den Ijssel ◽  
Sandra A. Zwijsen ◽  
Martin Smalbrugge ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Nursing Home ◽  
Frontotemporal Dementia ◽  
Neuropsychiatric Symptoms ◽  
Nursing Home Residents ◽  
Young Onset ◽  
Alzheimer Dementia ◽  
Young Onset Dementia ◽  
Dementia Subtype

Aims: The aims of this study are to (1) explore the determinants of quality of life (QoL) in nursing home residents with young-onset dementia (YOD), (2) investigate whether there are differences between dementia subtypes (Alzheimer dementia, vascular/mixed dementia, frontotemporal dementia, other) regarding these determinants, and (3) compare QoL profiles of YOD nursing home residents across dementia subtypes. Methods: This cross-sectional study included 207 nursing home residents. Multilevel modeling was used to determine the relationships between QoL and neuropsychiatric symptoms (NPS), dementia severity, psychotropic drug use (PDU), dementia subtype, age, and gender. Additional multilevel models were used to compare aspects of QoL between dementia subtypes. Results: Residents' QoL was negatively associated with advanced dementia, PDU, and NPS. In general, the relationships between the determinants and QoL were similar across the dementia subtypes. Aspects of QoL differed by dementia subtype. Residents with frontotemporal dementia showed less negative emotions, accepted more help and experienced better quality of relationships with professional caregivers, had a more positive self-image, felt more comfortable in the nursing home environment, and experienced lower quality of social relationships. Conclusions: Considering the high rates of NPS and PDU in YOD residents and their negative associations with QoL, we recommend emphasizing services to manage and reduce NPS and PDU in nursing home residents with YOD. Furthermore, our findings suggest accounting for differences in aspects of QoL by dementia subtype to address specific needs and thereby improve QoL.

scholarly journals Natural course of neuropsychiatric symptoms in nursing home patients with mental-physical multimorbidity in the first eight months after admission

2018 ◽  
Vol 24 (1) ◽  
pp. 155-161
Author(s):  
Anne van den Brink ◽  
Debby L. Gerritsen ◽  
Miranda M.H. de Valk ◽  
Richard Oude Voshaar ◽  
Raymond Koopmans
Keyword(s):  
Nursing Home ◽  
Neuropsychiatric Symptoms ◽  
Natural Course ◽  
Nursing Home Patients

The course of neuropsychiatric symptoms in nursing-home patients with dementia over a 53-month follow-up period

2013 ◽  
Vol 26 (1) ◽  
pp. 81-91 ◽  
Author(s):  
Geir Selbæk ◽  
Knut Engedal ◽  
Jūratė Šaltytė Benth ◽  
Sverre Bergh
Keyword(s):  
Nursing Home ◽  
Rating Scale ◽  
Neuropsychiatric Symptoms ◽  
Clinical Dementia Rating ◽  
Severe Dementia ◽  
Persistent Symptoms ◽  
Nursing Home Patients ◽  
Affective Symptoms ◽  
Clinically Significant

ABSTRACTBackground:Neuropsychiatric symptoms (NPS) are prevalent in nursing-home (NH) patients with dementia, but little is known about the long-term course of these symptoms.Methods:In this study, 931 NH patients with dementia took part in a prospective cohort study with four assessments over a 53-month follow-up period. NPS and level of dementia were assessed with the Neuropsychiatric Inventory scale and the Clinical Dementia Rating scale, respectively.Results:Mild, moderate, and severe dementia was present in 25%, 33%, and 42%, respectively. There was an increase in the severity of the dementia from the first to the fourth assessment. Agitation, irritability, disinhibition, and apathy were the most prevalent and persistent symptoms during the study period. The affective subsyndrome (depression and anxiety) became less severe, whereas the agitation subsyndrome (agitation/aggression, disinhibition, and irritability) and apathy increased in severity during the follow-up period. More severe dementia was associated with more severe agitation, psychosis, and apathy, but not more severe affective symptoms. Mild dementia was associated with an increase in the severity of psychosis, whereas moderate or severe dementia was associated with decreasing severity of psychosis over the follow-up period.Conclusion:Nearly all the patients experienced clinically significant NPS, but individual symptoms fluctuated. Affective symptoms became less severe, while agitation and apathy increased in severity. An increase in dementia severity was associated with an increase in the severity of agitation, psychosis, and apathy, but not affective symptoms. The results may have implications when planning evaluation, treatment, and the prevention of NPS in NH patients.

Racial Differences in Neuropsychiatric Symptoms Among Dementia Patients: A Comparison of African Americans and Whites

2000 ◽  
Vol 12 (S1) ◽  
pp. 395-402 ◽  
Author(s):  
Carl I. Cohen
Keyword(s):  
African American ◽  
Nursing Home ◽  
African Americans ◽  
Racial Differences ◽  
Neuropsychiatric Symptoms ◽  
Psychotic Symptoms ◽  
Sociodemographic Variable ◽  
Behavioral Disturbances ◽  
Dementia Patients ◽  
Nursing Home Patients

Race is a critical sociodemographic variable that may serve as a marker for genetic, clinical, cultural, and socioeconomic factors. There have been several studies that found differences between African Americans and Whites in the neuropsychiatric symptoms of dementia. There have been fairly consistent findings that psychotic symptoms—hallucinations and delusions—are more prevalent among African American patients with dementia (Cohen & Carlin, 1993; Cooper et al., 1991, Deutsch et al., 1991; Fabrega et al., 1988), and that depression is higher among Whites than among African Americans (Fabrega et al., 1988; Walker et al., 1995). One study by Class and colleagues (1996) also suggested that behavioral disturbances might be higher among White than among African American nursing home patients, a majority of whom had dementia.

The relationship between unmet care needs in young-onset dementia and the course of neuropsychiatric symptoms: a two-year follow-up study

2013 ◽  
Vol 26 (12) ◽  
pp. 1991-2000 ◽  
Author(s):  
Christian Bakker ◽  
Marjolein E. de Vugt ◽  
Deliane van Vliet ◽  
Frans R.J. Verhey ◽  
Yolande A. Pijnenburg ◽  
...  
Keyword(s):  
Unmet Needs ◽  
Neuropsychiatric Symptoms ◽  
The Elderly ◽  
Care Needs ◽  
Young Onset ◽  
Future Care ◽  
Camberwell Assessment Of Need ◽  
Young Onset Dementia ◽  
The Relationship ◽  
Level Of Agreement

ABSTRACTBackground:Little is known about care needs in young-onset dementia (YOD) patients, even though this information is essential for service provision and future care planning.We explored: (1) care needs of people with YOD, (2) the level of agreement within patient-caregiver dyads on care needs, and (3) the longitudinal relationship between unmet needs and neuropsychiatric symptoms.Methods:A community-based prospective study of 215 YOD patients-caregiver dyads. Care needs were assessed with the Camberwell Assessment of Need for the Elderly. The level of agreement between patient and caregivers’ report on care needs was calculated using κ coefficients. The relationship between unmet needs and neuropsychiatric symptoms over time, assessed with the Neuropsychiatric Inventory, was explored using linear mixed models.Results:Patients and caregivers generally agreed on the areas in which needs occurred. Only modest agreement existed within patient-caregiver dyads regarding whether needs could be met. Patients experienced high levels of unmet needs in areas such as daytime activities, social company, intimate relationships, and information, leading to an increase in neuropsychiatric symptoms.Conclusions:Our findings indicate that in YOD, there are specific areas of life in which unmet needs are more likely to occur. The high proportions of unmet needs and their relationship with neuropsychiatric symptoms warrant interventions that target neuropsychiatric symptoms as well as the prevention of unmet needs. This underlines the importance of the periodic investigation of care needs, in which patient and caregiver perspectives are considered complementary.

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