BACE1 and Mutated Presenilin-1 Differently Modulate Aβ40 and Aβ42 Levels and Cerebral Amyloidosis in APPDutch Transgenic Mice

2007 ◽  
Vol 4 (2-3) ◽  
pp. 127-135 ◽  
Author(s):  
Martin C. Herzig ◽  
Paolo Paganetti ◽  
Matthias Staufenbiel ◽  
Mathias Jucker
Keyword(s):  
Transgenic Mice ◽  
Presenilin 1 ◽  
Cerebral Amyloidosis

scholarly journals MyD88 Is Dispensable for Cerebral Amyloidosis and Neuroinflammation in APP/PS1 Transgenic Mice

2014 ◽  
Vol 184 (11) ◽  
pp. 2855-2861 ◽  
Author(s):  
Tara M. Weitz ◽  
David Gate ◽  
Kavon Rezai-Zadeh ◽  
Terrence Town
Keyword(s):  
Transgenic Mice ◽  
Cerebral Amyloidosis

scholarly journals P1-216: SEX-SPECIFIC PERTURBATIONS IN CEREBRAL AMYLOIDOSIS AND MICROGLIA PHENOTYPES IN ANTIBIOTIC-TREATED APPSWE /PS1L166P TRANSGENIC MICE

2019 ◽  
Vol 15 ◽  
pp. P319-P319
Author(s):  
Hemraj B. Dodiya ◽  
Thomas Kuntz ◽  
Shabana M. Shaik ◽  
Caroline Baufeld ◽  
Jeffrey Leibowitz ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Cerebral Amyloidosis

Coenzyme Q10 Attenuates β-Amyloid Pathology in the Aged Transgenic Mice with Alzheimer Presenilin 1 Mutation

2008 ◽  
Vol 34 (2) ◽  
pp. 165-171 ◽  
Author(s):  
Xifei Yang ◽  
Ying Yang ◽  
Geng Li ◽  
Jianzhi Wang ◽  
Edward S Yang
Keyword(s):  
Transgenic Mice ◽  
Coenzyme Q10 ◽  
Presenilin 1 ◽  
Amyloid Pathology ◽  
Presenilin 1 Mutation ◽  
Β Amyloid

scholarly journals Age-Related Vascular Pathology in Transgenic Mice Expressing Presenilin 1-Associated Familial Alzheimer's Disease Mutations

2010 ◽  
Vol 176 (1) ◽  
pp. 353-368 ◽  
Author(s):  
Miguel A. Gama Sosa ◽  
Rita De Gasperi ◽  
Anne B. Rocher ◽  
Athena Ching-Jung Wang ◽  
William G.M. Janssen ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Transgenic Mice ◽  
Vascular Pathology ◽  
Presenilin 1 ◽  
Familial Alzheimer’S Disease ◽  
Age Related ◽  
Disease Mutations ◽  
Familial Alzheimer's Disease

Tetracycline-controlled expression of presenilin-1 in transgenic mice

2000 ◽  
Vol 21 ◽  
pp. 154
Author(s):  
Joanna L. Jankowsky ◽  
Hilda H. Slunt ◽  
David R. Borchelt
Keyword(s):  
Transgenic Mice ◽  
Presenilin 1

Transcriptome Differences Between the Frontal Cortex and Hippocampus of Wild-Type and Humanized Presenilin-1 Transgenic Mice

2005 ◽  
Vol 13 (12) ◽  
pp. 1041-1051 ◽  
Author(s):  
Travis Unger ◽  
Zeljka Korade ◽  
Orly Lazarov ◽  
David Terrano ◽  
Nina F. Schor ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Frontal Cortex ◽  
Presenilin 1 ◽  
Wild Type

Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation

10.1038/8438 ◽  
1999 ◽  
Vol 5 (5) ◽  
pp. 560-564 ◽  
Author(s):  
De-Hua Chui ◽  
Hiroshi Tanahashi ◽  
Kazuharu Ozawa ◽  
Sachiya Ikeda ◽  
Frédéric Checler ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Amyloid Plaque ◽  
Plaque Formation ◽  
Presenilin 1

Effects of Alzheimer-related presenilin-1 mutations on oxidative stress and cell death in transgenic mice

2000 ◽  
Vol 21 ◽  
pp. 43
Author(s):  
Anne Eckert ◽  
Katharina Schindowski ◽  
Silke Leutner ◽  
Christian Luckhaus ◽  
Nathalie Touchet ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cell Death ◽  
Transgenic Mice ◽  
Presenilin 1
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