Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation

10.1038/8438 ◽  
1999 ◽  
Vol 5 (5) ◽  
pp. 560-564 ◽  
Author(s):  
De-Hua Chui ◽  
Hiroshi Tanahashi ◽  
Kazuharu Ozawa ◽  
Sachiya Ikeda ◽  
Frédéric Checler ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Amyloid Plaque ◽  
Plaque Formation ◽  
Presenilin 1

scholarly journals The Neuronal Adaptor Protein X11β Reduces Amyloid β-Protein Levels and Amyloid Plaque Formation in the Brains of Transgenic Mice

2004 ◽  
Vol 279 (47) ◽  
pp. 49099-49104 ◽  
Author(s):  
Ju-Hyun Lee ◽  
Kwok-Fai Lau ◽  
Michael S. Perkinton ◽  
Claire L. Standen ◽  
Boris Rogelj ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Amyloid Β ◽  
Adaptor Protein ◽  
Amyloid Plaque ◽  
Plaque Formation ◽  
Amyloid Β Protein ◽  
Protein Levels ◽  
Β Protein

Intraneuronal Aβ accumulation precedes plaque formation in β-amyloid precursor protein and presenilin-1 double-transgenic mice

2001 ◽  
Vol 306 (1-2) ◽  
pp. 116-120 ◽  
Author(s):  
Oliver Wirths ◽  
Gerd Multhaup ◽  
Christian Czech ◽  
Véronique Blanchard ◽  
Saliha Moussaoui ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Amyloid Precursor Protein ◽  
Plaque Formation ◽  
Precursor Protein ◽  
Presenilin 1 ◽  
Β Amyloid ◽  
Double Transgenic Mice ◽  
Intraneuronal Aβ

scholarly journals Intraneuronal APP/Aβ Trafficking and Plaque Formation in β-Amyloid Precursor Protein and Presenilin-1 Transgenic Mice

2006 ◽  
Vol 12 (3) ◽  
pp. 275-286 ◽  
Author(s):  
Oliver Wirths ◽  
Gerd Multhaup ◽  
Christian Czech ◽  
Nicole Feldmann ◽  
Véronique Blanchard ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Amyloid Precursor Protein ◽  
Plaque Formation ◽  
Precursor Protein ◽  
Presenilin 1 ◽  
Β Amyloid

scholarly journals Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice

2002 ◽  
Vol 99 (11) ◽  
pp. 7705-7710 ◽  
Author(s):  
J.-Y. Lee ◽  
T. B. Cole ◽  
R. D. Palmiter ◽  
S. W. Suh ◽  
J.-Y. Koh
Keyword(s):  
Transgenic Mice ◽  
Plaque Formation
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