Intracranial Navigation Using a Novel Device for Endoscope Fixation and Targeting: Technical Innovation

Objective: To measure the accuracy of a novel device in detecting Bradycardia andDesaturation (B&D) events and to determine its efficacy in resolving apneas innewborns with comparison to standard monitor (which only detects B&D eventsand alerts).Design: This was a prospective observational study.Setting: Sick Newborn Care Unit of a large tertiary referral hospital in Hyderabad,India.Methods: 31 newborns were provided with a novel device, which monitored oxygensaturation and pulse rate and alarmed when values dropped below a set thresholdwhich is referred as an event, henceforth. The novel device also provided footstimulation in response to above-mentioned events. When the monitor alarmed, anurse attended to the baby to confirm whether the baby was breathing and whetherthe event had been resolved by the device. If the event had not resolved, appropriateaction as per the standard-of-care was performed.Results: The novel device “ApneBootTM” positively detected B&D events 94.03% oftimes as compared to the standard reference monitor. 56 of 67 observed B&D eventswere visually confirmed to be apneas, indicating that 83.6% of B&D eventscoincided with apneas. Of the 56 apneic events, 50 were central apneas, of which 35were resolved by the novel device, making the device’s efficacy of apnea resolution70%.Conclusion: The results of the study indicate that this novel device “ApneBootTM”is very effective in detecting and alarming B&D events, which coincides with theapnea, and resolving it by providing foot stimulation.Keywords: Novel Device, Neonatal Apnea, Low Birth Weight, Body Temperature,Kangaroo Mother Care, Community Health,

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Regional Disparities of the Social Innovation Potential in the Visegrad Countries: Causes and Consequences

European Journal of Social Sciences Education and Research ◽

10.2478/ejser-2018-0004 ◽

2018 ◽

Vol 5 (1) ◽

pp. 36-42

Author(s):

György Kocziszky ◽

Dóra Szendi

Keyword(s):

Social Innovation ◽

Technical Innovation ◽

The European Union ◽

Social Culture ◽

Complex Character ◽

Innovation Potential ◽

The Social ◽

Territorial Disparities ◽

Active Contribution ◽

Visegrád Countries

Abstract The international literature is paying significant and increasing attention to the analysis of the regions’ innovation potential, and its active contribution to economic growth and competitiveness. Beside the classical, technical innovation, also the social innovation is getting even more emphasis. It can solve as alternative basically in the case of the peripheral territories. The convergence of peripheries is a stressed priority in the European Union. The territorial disparities are resulting in significant social and political problems also in the case of the Visegrad countries’ regions. The authors in their research represent a possible method for the measurement of regional (NUTS-2) level social innovation potential on the example of the Visegrad countries, and they also analyse the causes and consequences of disparities. The applied complex social innovation index can be calculated as a result of three pillars (economic, social, culture and attitude), and several components. As a result of the created patterns can be concluded that compared to the economic indicators, the disadvantage of the peripheries is not so significant in the case of the social innovation index, because of the complex character of the index. In the second part of the research, the authors analyse and evaluate also the methods, which can be adequate for increasing the social innovation potential.

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Faculty Opinions recommendation of Evaluation of a novel device for measuring patient compliance with oral appliances in the treatment of obstructive sleep apnea.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718356431.793494022 ◽

2014 ◽

Author(s):

Neil Freedman

Keyword(s):

Obstructive Sleep Apnea ◽

Sleep Apnea ◽

Patient Compliance ◽

Oral Appliances ◽

Novel Device ◽

Obstructive Sleep

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Measuring Earwax Cortisol Concentration Using a Non-Stressful Method (Preprint)

10.2196/preprints.19383 ◽

2020 ◽

Author(s):

Andrés Herane-Vives

Keyword(s):

Cortisol Level ◽

Local Stress ◽

Extraction Methods ◽

Cortisol Concentration ◽

The Novel ◽

Sampling Device ◽

Related Factors ◽

Novel Device ◽

Cortisol Levels ◽

The Right

BACKGROUND “Short-term” samples are not the most appropriate for reflecting Chronic Cortisol Concentration (CCC). Although hair is used for reflecting the systemic cortisol level over “long-term”, its use appears clinically problematic. Local stress and non-stress related factors may release a circumscribed cortisol secretion that is accumulated in hair. Non-stressful earwax extraction methods may provide a more accurate specimen to measure CCC. OBJECTIVE Correlate cortisol levels using hair, serum and earwax samples METHODS Earwax from both ears of 37 controls were extracted using a clinical procedure commonly associated with local pain. One month later, earwax from the left ear side was extracted using the same procedure, and earwax from the right ear side was comfortably extracted, using an earwax self-sampling device. Participants also provided one centimetre of hair that represented the retrospective month of cortisol output, and one serum sample that reflected the effect of systemic stressors on cortisol levels. Earwax (ECC), Hair (HCC) and Serum (SCC) Cortisol Concentration were correlated and compared. Confounders´ effect on cortisol levels were studied. RESULTS Serum showed the largest and hair the lowest cortisol concentration (p<0.01). Left-ECC was larger than Right-ECC (p=0.03). Right-ECC was the only sample unaffected by confounders (all p>0.05). Right-ECC and HCC showed the only significant association (r=0.39; p=0.03). CONCLUSIONS The self-sampling device did not represent a local stressor for the ceruminous glands. It provided the cortisol level with the least likely to be affected by confounding factors over the previous month. ECC using the novel device may constitute another accurate, but more suitable and affordable specimen for measuring CCC.

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Restoration and re-creation in the Eastern Han

10.1093/oso/9780198733119.003.0007 ◽

2018 ◽

Author(s):

Christopher Cullen

Keyword(s):

Han Dynasty ◽

Theory And Practice ◽

Early Years ◽

Technical Innovation ◽

Astronomical Observation ◽

Fundamental Innovation ◽

The Creation ◽

Zhang Heng ◽

Eastern Han ◽

New System

We look first at the situation in the early years of the restored Han dynasty. Liu Xin’s system continued in use for more than half a century. Then, in 85 CE, Liu Xin’s system was replaced. We have records of the practical and theoretical grounds on which the old system was rejected, and of the creation and implementation of a new system. Next we follow the story of how c. 92 CE Jia Kui advocated a fundamental innovation in both theory and practice: he insisted on the ecliptic as being central to astronomical observation and calculation. The richness of records from this period makes it easy to tell a detailed story of technical innovation in its fullest context, leading up to the work of Zhang Heng (78–139 CE), for whom astronomical calculation was just one of several fields in which he gained a reputation for exceptional originality.

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A Problem in the Making: How Firms Formulate Sharable Problems for Open Innovation Contests

10.1093/oso/9780198816225.003.0006 ◽

2018 ◽

Cited By ~ 1

Author(s):

Martin W. Wallin ◽

Georg von Krogh ◽

Jan Henrik Sieg

Keyword(s):

Knowledge Creation ◽

Open Innovation ◽

Problem Formulation ◽

Theoretical Framework ◽

Monetary Reward ◽

Technical Innovation ◽

Prior Work ◽

Exploratory Case Study ◽

External Sources

Crowdsourcing in the form of innovation contests stimulates knowledge creation external to the firm by distributing technical, innovation-related problems to external solvers and by proposing a fixed monetary reward for solutions. While prior work demonstrates that innovation contests can generate solutions of value to the firm, little is known about how problems are formulated for such contests. We investigate problem formulation in a multiple exploratory case study of seven firms and inductively develop a theoretical framework that explains the mechanisms of formulating sharable problems for innovation contests. The chapter contributes to the literatures on crowdsourcing and open innovation by providing a rare account of the intra-organizational implications of engaging in innovation contests and by providing initial clues to problem formulation—a critical antecedent to firms’ ability to leverage external sources of innovation.

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The Opera-Telephone in Munich

10.1093/oxfordhb/9780190466961.013.17 ◽

2018 ◽

Author(s):

Sonja Neumann

Keyword(s):

Social Economic ◽

Historical Analysis ◽

Technical Innovation ◽

Reciprocal Relation ◽

Special Means ◽

Private And Public ◽

Listening Experience ◽

Visual Element ◽

The Impact ◽

Technical Products

Through a cultural-historical analysis, the chapter portrays the Opera-Telephone in Munich as a special means of listening and explores its technical, social, economic, and psychological aspects. These aspects strongly reflect the reciprocal relation of technical innovation and listening to music, for example, by emphasizing the meaning of live broadcasting for listening habits and by highlighting the impact of headphone use on aural perception. The latter practice enables the transfer of the multidimensional opera event into a pure listening experience as the visual element is eliminated. The Opera-Telephone also serves to illustrate matters of social status in regard to private and public listening. In this way, opera was incorporated into the marketing of modern technical products.

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