Preclinical Application of Radioimmunoguided Surgery Using Anti-Carcinoembryonic Antigen Biparatopic Antibody in the Colon Cancer

2005 ◽  
Vol 37 (1) ◽  
pp. 36-44 ◽  
Author(s):  
J.C. Kim ◽  
S.A. Roh ◽  
K.H. Koo ◽  
Y.K. Cho ◽  
H.C. Kim ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Carcinoembryonic Antigen ◽  
Radioimmunoguided Surgery

Concurrent measurements of carcinoembryonic antigen, glucosephosphate isomerase, gamma-glutamyltransferase, and lactate dehydrogenase in malignant, normal adult, and fetal colon tissues.

1980 ◽  
Vol 26 (13) ◽  
pp. 1809-1812 ◽  
Author(s):  
D D Munjal
Keyword(s):  
Colon Cancer ◽  
Lactate Dehydrogenase ◽  
Carcinoembryonic Antigen ◽  
Tumor Tissue ◽  
Human Colon ◽  
Normal Adult ◽  
Metastatic Colon Cancer ◽  
Glucosephosphate Isomerase ◽  
Adult Human ◽  
Fetal Organs

Abstract Carcinoembryonic antigen and activities of glucosephosphate isomerase (EC 5.3.1.9), γ-glutamyltransferase (EC 2.3.2.2), and lactate dehydrogenase (EC 1.1.1.27) were measured in aqueous extracts of fetal, normal adult, and malignant human colon tissues. Fetal colon, as well as primary and metastatic colon tumor tissue, showed higher activities of these analytes than did normal adult human colon. Liver metastases of colon cancer gave the highest values, normal adult human colon the lowest. Statistically, these differences were more striking in the case of carcinoembryonic antigen and glucosephosphate isomerase than for γ-glutamyltransferase or lactate dehydrogenase. In contrast to the other markers, γ-glutamyltransferase activity was lower in fetal organs than in normal adult colon and colon tumors. These results are consistent with earlier observations that activities of these markers are significantly increased in the blood of patients with metastatic colon cancer.

scholarly journals Carcinoembryonic Antigen Elevation in a Patient with SARS-CoV-2 and a History of Colon Cancer

2021 ◽  
pp. 802-805
Author(s):  
Taha Alrifai ◽  
Anita Sharko ◽  
William T. Leslie
Keyword(s):  
Health Care ◽  
Colon Cancer ◽  
Severe Acute Respiratory Syndrome ◽  
Carcinoembryonic Antigen ◽  
Health Care Delivery ◽  
Care Delivery ◽  
Prognostic Biomarkers ◽  
Diagnosis And Treatment ◽  
Routine Surveillance ◽  
History Of

The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic continues to affect millions of people and impact health-care delivery worldwide. New data and insights into the diagnosis and treatment of SARS-CoV-2 are emerging rapidly. Several prognostic biomarkers have been studied in patients with SARS-CoV-2. Among those biomarkers is the carcinoembryonic antigen (CEA). We report the case of a 46-year-old male with a history of colon cancer who was found to have an elevated CEA level during routine surveillance. Further workup confirmed a diagnosis of SARS-CoV-2 infection. The CEA level normalized with the resolution of the infection.

Conformational epitopes specific to carcinoembryonic antigen defined by monoclonal antibodies raised against colon cancer xenografts

1989 ◽  
Vol 42 (1) ◽  
pp. 39-46 ◽  
Author(s):  
Yoichi Sakurai ◽  
Setsuo Hirohashi ◽  
Takashi Ohishi ◽  
Yukio Shimosato ◽  
Susumu Kodaira ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Monoclonal Antibodies ◽  
Carcinoembryonic Antigen ◽  
Conformational Epitopes

Carcinoembryonic antigen (CEA) levels and tumor histology in colon cancer

1975 ◽  
Vol 18 (3) ◽  
pp. 257-261 ◽  
Author(s):  
Brack A. Bivins ◽  
William R. Meeker ◽  
Ward O. Griffen ◽  
Jorge Pellegrini ◽  
Joseph C. Parker
Keyword(s):  
Colon Cancer ◽  
Carcinoembryonic Antigen ◽  
Tumor Histology
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