Effects of Endothelin-1 on Human Trabecular Meshwork Cell Contraction

2005 ◽  
Vol 37 (1) ◽  
pp. 43-49 ◽  
Author(s):  
Mauro Cellini ◽  
Piera Versura ◽  
Davide Trerè ◽  
Emilio C. Campos
Keyword(s):  
Trabecular Meshwork ◽  
Cell Contraction ◽  
Endothelin 1 ◽  
Trabecular Meshwork Cell

scholarly journals Regulation of Trabecular Meshwork Cell Contraction and Intraocular Pressure by miR-200c

PLoS ONE ◽  
2012 ◽  
Vol 7 (12) ◽  
pp. e51688 ◽  
Author(s):  
Coralia Luna ◽  
Guorong Li ◽  
Jianyong Huang ◽  
Jianming Qiu ◽  
Jing Wu ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Trabecular Meshwork ◽  
Cell Contraction ◽  
Trabecular Meshwork Cell

Regulation of Endothelin-1–Induced Trabecular Meshwork Cell Contractility by Latanoprostene Bunod

2015 ◽  
Vol 56 (6) ◽  
pp. 4108 ◽  
Author(s):  
Megan E. Cavet ◽  
Thomas R. Vollmer ◽  
Karen L. Harrington ◽  
Karl VanDerMeid ◽  
Mary E. Richardson
Keyword(s):  
Trabecular Meshwork ◽  
Cell Contractility ◽  
Endothelin 1 ◽  
Trabecular Meshwork Cell

Circumferential trabecular meshwork cell density in the human eye

2021 ◽  
Vol 205 ◽  
pp. 108494
Author(s):  
Markus H. Kuehn ◽  
Janice A. Vranka ◽  
David Wadkins ◽  
Thomas Jackson ◽  
Lin Cheng ◽  
...  
Keyword(s):  
Cell Density ◽  
Trabecular Meshwork ◽  
Human Eye ◽  
Trabecular Meshwork Cell

scholarly journals Cyclic Mechanical Stress and Trabecular Meshwork Cell Contractility

2009 ◽  
Vol 50 (8) ◽  
pp. 3826 ◽  
Author(s):  
Renata F. Ramos ◽  
Grant M. Sumida ◽  
W. Daniel Stamer
Keyword(s):  
Mechanical Stress ◽  
Trabecular Meshwork ◽  
Cell Contractility ◽  
Trabecular Meshwork Cell

Cardiovascular and gill microcirculatory effects of endothelin-1 in atlantic cod: evidence for pillar cell contraction

1999 ◽  
Vol 202 (9) ◽  
pp. 1151-1157 ◽  
Author(s):  
K.O. Stenslokken ◽  
L. Sundin ◽  
G.E. Nilsson
Keyword(s):  
Vascular Resistance ◽  
Gadus Morhua ◽  
Atlantic Cod ◽  
Venous Blood ◽  
Cell Diameter ◽  
Cell Contraction ◽  
Pillar Cell ◽  
Endothelin 1 ◽  
Etb Receptor ◽  
Gill Lamellae

Endothelin-1 (ET-1) has been shown to cause a considerable increase in the vascular resistance of fish gills. In trout, recent evidence suggest that this is the result of pillar cell contraction in the gill lamellae. Using epi-illumination microscopy to observe the gill lamellae of anaesthetised Atlantic cod (Gadus morhua), we show that ET-1 (100 ng kg-1, injected into the ventral aorta) causes an increase in pillar cell diameter, consistent with pillar cell contraction, and a shift of intralamellar blood flow from the lamellar sheet to the outer marginal channels. Simultaneously, there was an increase in ventral aortic blood pressure, a reduction in cardiac output, an increase in gill vascular resistance and a reduction in the oxygen partial pressure of venous blood. All these effects were blocked by the ETA/ETB receptor antagonist bosentan (5 mg kg-1). Pillar cell contraction is likely to be a mechanism for matching the functional respiratory surface area with the instantaneous respiratory needs of the fish.

Caveolin‐1 regulates human trabecular meshwork cell adhesion, endocytosis, and autophagy

2019 ◽  
Vol 120 (8) ◽  
pp. 13382-13391 ◽  
Author(s):  
Zhenggen Wu ◽  
Chukai Huang ◽  
Ciyan Xu ◽  
Lijing Xie ◽  
Jia‐Jian Liang ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Trabecular Meshwork ◽  
Caveolin 1 ◽  
Trabecular Meshwork Cell

Effects of Unoprostone and Endothelin 1 on L-Type Channel Currents in Human Trabecular Meshwork Cells

2005 ◽  
Vol 37 (6) ◽  
pp. 293-300 ◽  
Author(s):  
Hagen Thieme ◽  
Kirsten Steinhausen ◽  
Anna Ottlecz ◽  
George N. Lambrou ◽  
Olaf Strauss ◽  
...  
Keyword(s):  
Trabecular Meshwork ◽  
Endothelin 1 ◽  
Trabecular Meshwork Cells ◽  
Channel Currents
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