Use of Near Infrared Spectroscopy for Estimation of Peripheral Venous Saturation in Newborns: Comparison with Co-Oximetry of Central Venous Blood

Neonatology ◽  
2002 ◽  
Vol 82 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Rikke Bay-Hansen ◽  
Betina Elfving ◽  
Gorm Greisen
Ozone Therapy ◽  
2017 ◽  
Vol 1 (3) ◽  
pp. 56 ◽  
Author(s):  
Daniele Rimini ◽  
Filippo Molinari ◽  
William Liboni ◽  
Vincenzo Simonetti ◽  
Marianno Franzini

Ozone major autohemotherapy (O-MAHT) is a way of ozonetherapy administration consisting of drawing patient’s venous blood, mixing with oxygen/ozone, and reinfusing it into the vein. Some ozone therapists reported side effects during the O-MAHT, but the origin has not been described yet. We investigated the effect of blood drawing velocity during O-MAHT to see its effects on the vascular system and symptomatology. We administered O-MAHT to 11 subjects, and we interleaved fast and slow reinfusions. We monitored cerebral macrocirculation with transcranial Doppler (TCD) and tissue microcirculation with near-infrared spectroscopy (NIRS). Annoying symptoms appeared just during the fast reinfusion periods. NIRS and TCD parameters revealed vasoconstriction during fast reinfusion and improved metabolism during slow reinfusion. Overall, our investigation well discriminated fast from slow reinfusion velocity.


Biosensors ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 71
Author(s):  
Tomas Ysehak Abay ◽  
Kamran Shafqat ◽  
Panayiotis A. Kyriacou

Photoplethysmography (PPG) signals from the forehead can be used in pulse oximetry as they are less affected by vasoconstriction compared to fingers. However, the increase in venous blood caused by the positioning of the patient can deteriorate the signals and cause erroneous estimations of the arterial oxygen saturation. To date, there is no method to measure this venous presence under the PPG sensor. This study investigates the feasibility of using PPG signals from the forehead in an effort to estimate relative changes in haemoglobin concentrations that could reveal these posture-induced changes. Two identical reflectance PPG sensors were placed on two different positions on the forehead (above the eyebrow and on top of a large vein) in 16 healthy volunteers during a head-down tilt protocol. Relative changes in oxygenated ( Δ HbO 2 ), reduced ( Δ HHb) and total ( Δ tHb) haemoglobin were estimated from the PPG signals and the trends were compared with reference Near Infrared Spectroscopy (NIRS) measurements. Also, the signals from the two PPG sensors were analysed in order to reveal any difference due to the positioning of the sensor. Δ HbO 2 , Δ HHb and Δ tHb estimated from the forehead PPGs trended well with the same parameters from the reference NIRS. However, placing the sensor over a large vasculature reduces trending against NIRS, introduces biases as well as increases the variability of the changes in Δ HHb. Forehead PPG signals can be used to measure perfusion changes to reveal venous pooling induced by the positioning of the subject. Placing the sensor above the eyebrow and away from large vasculature avoids biases and large variability in the measurements.


2017 ◽  
Vol 22 (2) ◽  
pp. 025001 ◽  
Author(s):  
Martin B. Rasmussen ◽  
Vibeke R. Eriksen ◽  
Bjørn Andresen ◽  
Simon Hyttel-Sørensen ◽  
Gorm Greisen

2000 ◽  
Vol 5 (2) ◽  
pp. 155 ◽  
Author(s):  
M. Nitzan ◽  
A. Babchenko ◽  
B. Khanokh ◽  
H. Taitelbaum

1999 ◽  
Vol 24 (3) ◽  
pp. 216-230 ◽  
Author(s):  
Andrew Hicks ◽  
Stuart Mcgill ◽  
Richard L. Hughson

The relationship between tissue oxygenation measured by near-infrared spectroscopy (NIRS) and forearm muscle blood flow (FBF) measured by Doppler ultrasound was tested during isometric contractions at 10 and 30% maximal voluntary contraction (MVC) under conditions of normoxia and hypoxia (14% inspired O2). Six subjects maintained contractions at 10% MVCfor 5 min and at 30% for 2 min in both gas conditions. FBF was elevated during exercise at 10% MVC in hypoxia compared to normoxia, but there was no further increase in flow at 30% MVC. Median power frequency calculations from electromyographic recordings suggested progressive development of fatigue throughout both 10 and 30% MVC contractions. NIRS indicated no change in muscle oxygenation at 10% MVC, but deep venous blood O2 saturation was reduced in normoxia and more so in hypoxia. At 30% MVC, both NIRS and venous O2 saturation were reduced, with no effect of hypoxia on the NIRS signal. While NIRS might provide an indication of muscle oxygenation during isometric exercise, the conflicting findings for NIRS and direct venous blood sampling at 10 vs. 30% MVC suggest caution in the application of this noninvasive technique. Key words: exercise, Doppler ultrasound, venous blood. O2 saturation, hemoglobin


2001 ◽  
Vol 90 (5) ◽  
pp. 1657-1662 ◽  
Author(s):  
Yoko Hoshi ◽  
Norio Kobayashi ◽  
Mamoru Tamura

Using a newly developed perfused rat brain model, we examined direct effects of each change in cerebral blood flow (CBF) and oxygen metabolic rate on cerebral hemoglobin oxygenation to interpret near-infrared spectroscopy signals. Changes in CBF and total hemoglobin (tHb) were in parallel, although tHb showed no change when changes in CBF were small (≤10%). Increasing CBF caused an increase in oxygenated hemoglobin (HbO2) and a decrease in deoxygenated hemoglobin (deoxy-Hb). Decreasing CBF was accompanied by a decrease in HbO2, whereas changes in direction of deoxy-Hb were various. Cerebral blood congestion caused increases in HbO2, deoxy-Hb, and tHb. Administration of pentylenetetrazole without increasing the flow rate caused increases in HbO2 and tHb with a decrease in deoxy-Hb. There were no significant differences in venous oxygen saturation before vs. during seizure. These results suggest that, in activation studies with near-infrared spectroscopy, HbO2 is the most sensitive indicator of changes in CBF, and the direction of changes in deoxy-Hb is determined by the degree of changes in venous blood oxygenation and volume.


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