Measurement of oxygen saturation in venous blood by dynamic near infrared spectroscopy

Background: Accurate detection of cerebral oxygen saturation (rSO2) may be useful for neonatal brain injury prevention, and the normal range of rSO2 of neonates at high altitude remained unclear. Objective: To compare cerebral rSO2 and cerebral fractional tissue oxygen extraction (cFTOE) at high-altitude and low-altitude areas in healthy neonates and neonates with underlying diseases. Methods: 515 neonates from low-altitude areas and 151 from Tibet were enrolled. These neonates were assigned into the normal group, hypoxic-ischemic encephalopathy (HIE) group, and other diseases group. Near-infrared spectroscopy was used to measure rSO2 in neonates within 24 h after admission. The differences of rSO2, pulse oxygen saturation (SpO2), and cFTOE levels were compared between neonates from low- and high-altitude areas. Results: (1) The mean rSO2 and cFTOE levels in normal neonates from Tibet were 55.0 ± 6.4% and 32.6 ± 8.5%, significantly lower than those from low-altitude areas (p < 0.05). (2) At high altitude, neonates with HIE, pneumonia (p < 0.05), anemia, and congenital heart disease (p < 0.05) have higher cFTOE than healthy neonates. (3) Compared with HIE neonates from plain areas, neonates with HIE at higher altitude had lower cFTOE (p < 0.05), while neonates with heart disease in plateau areas had higher cFTOE than those in plain areas (p < 0.05). Conclusions: The rSO2 and cFTOE levels in normal neonates from high-altitude areas are lower than neonates from the low-altitude areas. Lower cFTOE is possibly because of an increase in blood flow to the brain, and this may be adversely affected by disease states which may increase the risk of brain injury.

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The speed of reinfusion affects the vascular system during ozone major autohemotherapy

Ozone Therapy ◽

10.4081/ozone.2016.6477 ◽

2017 ◽

Vol 1 (3) ◽

pp. 56 ◽

Cited By ~ 1

Author(s):

Daniele Rimini ◽

Filippo Molinari ◽

William Liboni ◽

Vincenzo Simonetti ◽

Marianno Franzini

Keyword(s):

Infrared Spectroscopy ◽

Side Effects ◽

Near Infrared Spectroscopy ◽

Transcranial Doppler ◽

Near Infrared ◽

Vascular System ◽

Venous Blood ◽

Blood Drawing

Ozone major autohemotherapy (O-MAHT) is a way of ozonetherapy administration consisting of drawing patient’s venous blood, mixing with oxygen/ozone, and reinfusing it into the vein. Some ozone therapists reported side effects during the O-MAHT, but the origin has not been described yet. We investigated the effect of blood drawing velocity during O-MAHT to see its effects on the vascular system and symptomatology. We administered O-MAHT to 11 subjects, and we interleaved fast and slow reinfusions. We monitored cerebral macrocirculation with transcranial Doppler (TCD) and tissue microcirculation with near-infrared spectroscopy (NIRS). Annoying symptoms appeared just during the fast reinfusion periods. NIRS and TCD parameters revealed vasoconstriction during fast reinfusion and improved metabolism during slow reinfusion. Overall, our investigation well discriminated fast from slow reinfusion velocity.

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Near-infrared spectroscopy monitoring tissue oxygen saturation after cardiac surgery

Critical Care ◽

10.1186/cc7403 ◽

2009 ◽

Vol 13 (Suppl 1) ◽

pp. P239

Author(s):

R Kopp ◽

S Rex ◽

K Dommann ◽

G Schälte ◽

G Dohmen ◽

...

Keyword(s):

Cardiac Surgery ◽

Infrared Spectroscopy ◽

Oxygen Saturation ◽

Near Infrared Spectroscopy ◽

Near Infrared ◽

Tissue Oxygen Saturation ◽

Tissue Oxygen

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