Infants of Mothers with HELLP Syndrome Compensate Intrauterine Growth Retardation Faster than Unaffected Premature Infants: Does HELLP Change Fetal Programming?

Neonatology ◽  
2002 ◽  
Vol 82 (3) ◽  
pp. 174-180 ◽  
Author(s):  
Thomas Brune ◽  
Bade Baytar-Dagly ◽  
Roland Hentschel ◽  
Erik Harms ◽  
Frank Louwen
Keyword(s):  
Premature Infants ◽  
Growth Retardation ◽  
Fetal Programming ◽  
Hellp Syndrome ◽  
Intrauterine Growth Retardation ◽  
Intrauterine Growth

HUMAN FETAL GROWTH RETARDATION: I. CLINICAL FEATURES OF SAMPLE WITH INTRAUTERINE GROWTH RETARDATION

PEDIATRICS ◽  
1972 ◽  
Vol 50 (4) ◽  
pp. 547-558
Author(s):  
J. Urrusti ◽  
P. Yoshida ◽  
L. Velasco ◽  
S. Frenk ◽  
A. Rosado ◽  
...  
Keyword(s):  
Birth Weight ◽  
Premature Infants ◽  
Fetal Growth ◽  
Gestational Age ◽  
Growth Retardation ◽  
Intrauterine Growth Retardation ◽  
Fetal Growth Retardation ◽  
Neonatal Deaths ◽  
Intrauterine Growth ◽  
Normal Term

Intrauterine growth was assessed in a series of 128 cases. Thirty-six infants were small for gestational age, and showed the usual signs of intrauterine growth retardation (IUM). The head circumference of these infants was small, with reference to normal term babies (FT) and comparable to premature infants, appropriately sized for a gestational age (ACA) five weeks less than that of the IUM's. There were 12 neonatal deaths, three among IUM infants within 24 hours and nine in the low birth weight AGA group within 72 hours. The mothers of these three groups of infants were similar with respect to age, weight, height, nutritional patterns, and prior pregnancy histories.

scholarly journals Fetal Programming Is Deeply Related to Maternal Selenium Status and Oxidative Balance; Experimental Offspring Health Repercussions

Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 2085
Author(s):  
María Luisa Ojeda ◽  
Fátima Nogales ◽  
Inés Romero-Herrera ◽  
Olimpia Carreras
Keyword(s):  
Oxidative Stress ◽  
Growth Retardation ◽  
Fetal Programming ◽  
Intrauterine Growth Retardation ◽  
Antioxidant Properties ◽  
Experimental Studies ◽  
Abnormal Development ◽  
Endocrine Regulation ◽  
Intrauterine Growth ◽  
Oxidative Balance

Nutrients consumed by mothers during pregnancy and lactation can exert permanent effects upon infant developing tissues, which could represent an important risk factor for diseases during adulthood. One of the important nutrients that contributes to regulating the cell cycle and tissue development and functionality is the trace element selenium (Se). Maternal Se requirements increase during gestation and lactation. Se performs its biological action by forming part of 25 selenoproteins, most of which have antioxidant properties, such as glutathione peroxidases (GPxs) and selenoprotein P (SELENOP). These are also related to endocrine regulation, appetite, growth and energy homeostasis. In experimental studies, it has been found that low dietary maternal Se supply leads to an important oxidative disruption in dams and in their progeny. This oxidative stress deeply affects gestational parameters, and leads to intrauterine growth retardation and abnormal development of tissues, which is related to endocrine metabolic imbalance. Childhood pathologies related to oxidative stress during pregnancy and/or lactation, leading to metabolic programing disorders like fetal alcohol spectrum disorders (FASD), have been associated with a low maternal Se status and intrauterine growth retardation. In this context, Se supplementation therapy to alcoholic dams avoids growth retardation, hepatic oxidation and improves gestational and breastfeeding parameters in FASD pups. This review is focused on the important role that Se plays during intrauterine and breastfeeding development, in order to highlight it as a marker and/or a nutritional strategy to avoid diverse fetal programming disorders related to oxidative stress.

scholarly journals Vegetative regulation in the first three months of life in premature infants born with intrauterine growth retardation

2018 ◽  
Vol 9 (4) ◽  
pp. 36-43
Author(s):  
Elena A. Bliznetsova ◽  
Liudmila K. Antonova ◽  
Alexandr N. Malinin
Keyword(s):  
Body Weight ◽  
Preterm Infants ◽  
Premature Infants ◽  
Growth Retardation ◽  
Intrauterine Growth Retardation ◽  
Wave Spectrum ◽  
High Frequency Component ◽  
Control Group ◽  
Intrauterine Growth ◽  
Vegetative Regulation

Goal. To study the dynamics of vegetative states in preterm infants with intrauterine growth retardation (IUGR) during the first three months of life. Materials and methods. Examined 34 preterm infants with IUGR – 1st group (GA – 33,3 ± 1,4 weeks, body weight – 1557,8 ± 63,8 g, length – 41,2 ± 1,7 cm) at the age of 5 days and 3 months of life; 51 premature infants without IUGR (GA – 33,2 ± 1,02 weeks, body weight 2062,0 ± 63,9 grams, length – 44,0 ± 1,4 cm) – 2nd group; a control group included 31 healthy full-term infants (GA – 38,8 ± 1,5 weeks, body weight – 3355,4 ± 147,6 grams, length – 52,7 ± 2,3 cm). The vegetative tester “Polispektr-8E/88” (2000 Hz, 12 bit), from the Russian firm “Neurosoft”, was used. Indicators of the cardiointervalogram (CIG) and spectrogram were determined in the baseline sample and in the orthostatic test (tilt-test). Results. Among the indicators of CIG there was a noticeable decrease of mode (Mo, s) in 2 groups of preterm infants at 5 days of life (p < 0,05) and an increase in stress-index by 3 months of age in 1 group (p < 0,05). The study revealed the predominance in the structure of the wave spectrum of the VLF-component in all groups of children to 3 months; children 1 group had a lower value of this indicator, but they also had a higher proportion of high frequency component (HF, %) (p < 0,05). Vagotonic initial vegetative tonus (IVT) was defined only in 1 group, while the frequency of sympathicotonic and hypersympathicotonic IVT decreased (p < 0,05). Asympathicotonia vegetative reactivity (AST VR) in premature infants with IUGR was increased from 38, to 72,7% to 3 months (p < 0,05). Conclusion. The study revealed the lack of influence of the Central contour vegetative regulation, more intense adaptation and high exhaustion of the functional reserve in preterm infants with IUGR to 3 months of life.

scholarly journals 147 Abdominal Organ Growth in Intrauterine Growth Retardation: Fetal “Programming” of Diseases Later in Life

2004 ◽  
Vol 56 (3) ◽  
pp. 489-489
Author(s):  
G Latini ◽  
B De Mitri ◽  
A Del Vecchio ◽  
G Chitano ◽  
C De Felice ◽  
...  
Keyword(s):  
Growth Retardation ◽  
Fetal Programming ◽  
Intrauterine Growth Retardation ◽  
Abdominal Organ ◽  
Organ Growth ◽  
Intrauterine Growth

scholarly journals Factor VIII levels and the risk of pre-eclampsia, HELLP syndrome, pregnancy related hypertension and severe intrauterine growth retardation

2005 ◽  
Vol 115 (5) ◽  
pp. 387-392 ◽  
Author(s):  
C.P.J. Witsenburg ◽  
F.R. Rosendaal ◽  
J.M. Middeldorp ◽  
F.J.M. Van der Meer ◽  
S.A. Scherjon
Keyword(s):  
Factor Viii ◽  
Growth Retardation ◽  
Hellp Syndrome ◽  
Intrauterine Growth Retardation ◽  
Intrauterine Growth
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