Induction of Apoptosis in Rabbit Kidney Cell under High-Level Expression of Bovine Herpesvirus 1 Us ORF8 Product

Intervirology ◽  
2002 ◽  
Vol 45 (2) ◽  
pp. 85-93 ◽  
Author(s):  
Kazuo Nakamichi ◽  
Yasunobu Matsumoto ◽  
Yukinobu Tohya ◽  
Haruki Otsuka
Keyword(s):  
Kidney Cell ◽  
Bovine Herpesvirus ◽  
Rabbit Kidney ◽  
High Level Expression ◽  
Bovine Herpesvirus 1 ◽  
Herpesvirus 1 ◽  
Induction Of Apoptosis ◽  
High Level ◽  
Rabbit Kidney Cell

scholarly journals Bovine Herpesvirus 1 Glycoprotein G Is Required for Prevention of Apoptosis and Efficient Viral Growth in Rabbit Kidney Cells

Virology ◽  
2001 ◽  
Vol 279 (2) ◽  
pp. 488-498 ◽  
Author(s):  
Kazuo Nakamichi ◽  
Daisuke Kuroki ◽  
Yasunobu Matsumoto ◽  
Haruki Otsuka
Keyword(s):  
Bovine Herpesvirus ◽  
Rabbit Kidney ◽  
Kidney Cells ◽  
Bovine Herpesvirus 1 ◽  
Viral Growth ◽  
Glycoprotein G ◽  
Herpesvirus 1

Inhibition of T-lymphocyte mitogenic responses and effects on cell functions by bovine herpesvirus 1.

1989 ◽  
Vol 63 (4) ◽  
pp. 1525-1530 ◽  
Author(s):  
J J Carter ◽  
A D Weinberg ◽  
A Pollard ◽  
R Reeves ◽  
J A Magnuson ◽  
...  
Keyword(s):  
T Lymphocyte ◽  
Bovine Herpesvirus ◽  
Bovine Herpesvirus 1 ◽  
Cell Functions ◽  
Herpesvirus 1

scholarly journals Neutralizing Antibodies to Bovine Herpesvirus 1 in Reindeer

1982 ◽  
Vol 23 (4) ◽  
pp. 565-569
Author(s):  
C. Ek-Kommonen ◽  
P. Veijalainen ◽  
M. Rantala ◽  
E. Neuvonen
Keyword(s):  
Neutralizing Antibodies ◽  
Bovine Herpesvirus ◽  
Bovine Herpesvirus 1 ◽  
Herpesvirus 1

scholarly journals Regulation of Krüppel-Like Factor 15 Expression by Herpes Simplex Virus Type 1 or Bovine Herpesvirus 1 Productive Infection

Viruses ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1148
Author(s):  
Fouad S. El-mayet ◽  
Kelly S. Harrison ◽  
Clinton Jones
Keyword(s):  
Steady State ◽  
Promoter Activity ◽  
Bovine Herpesvirus ◽  
Productive Infection ◽  
Bovine Herpesvirus 1 ◽  
Protein Levels ◽  
Herpesvirus 1 ◽  
Simplex Virus ◽  
Hsv 1

Expression of Krüppel-like factor 15 (KLF15), a stress-induced transcription factor, is induced during bovine herpesvirus 1 (BoHV-1) reactivation from latency, and KLF15 stimulates BoHV-1 replication. Transient transfection studies revealed that KLF15 and glucocorticoid receptor (GR) cooperatively transactivate the BoHV-1-immediate-early transcription unit 1 (IEtu1), herpes simplex virus type 1 (HSV-1) infected cell protein 0 (ICP0), and ICP4 promoters. The IEtu1 promoter drives expression of bICP0 and bICP4, two key BoHV-1 transcriptional regulatory proteins. Based on these studies, we hypothesized infection is a stressful stimulus that increases KLF15 expression and enhances productive infection. New studies demonstrated that silencing KLF15 impaired HSV-1 productive infection, and KLF15 steady-state protein levels were increased at late stages of productive infection. KLF15 was primarily localized to the nucleus following infection of cultured cells with HSV-1, but not BoHV-1. When cells were transfected with a KLF15 promoter construct and then infected with HSV-1, promoter activity was significantly increased. The ICP0 gene, and to a lesser extent, bICP0 transactivated the KLF15 promoter in the absence of other viral proteins. In contrast, BoHV-1 or HSV-1 encoded VP16 had no effect on KLF15 promoter activity. Collectively, these studies revealed that HSV-1 and BoHV-1 productive infection increased KLF15 steady-state protein levels, which correlated with increased virus production.

EvaGreen-based Multiplex Real-time PCR Assay for Rapid Differentiation of Wild-Type and Glycoprotein E-Deleted Bovine Herpesvirus-1 Strains

2017 ◽  
Vol 28 (4) ◽  
pp. 248-252 ◽  
Author(s):  
Sachin S. Pawar ◽  
Chetan D. Meshram ◽  
Niraj K. Singh ◽  
Mohini Saini ◽  
B. P. Mishra ◽  
...  
Keyword(s):  
Real Time ◽  
Real Time Pcr ◽  
Bovine Herpesvirus ◽  
Wild Type ◽  
Pcr Assay ◽  
Bovine Herpesvirus 1 ◽  
Glycoprotein E ◽  
Herpesvirus 1

Rubella Neutralizing Antibody Determinations with the Rabbit Kidney Cell Strain LLC-RK1

1968 ◽  
Vol 129 (2) ◽  
pp. 650-652 ◽  
Author(s):  
D. A. Fuccillo ◽  
J. L. Sever ◽  
G. L. Gitnick ◽  
R. G. Traub ◽  
R. J. Huebner
Keyword(s):  
Kidney Cell ◽  
Neutralizing Antibody ◽  
Cell Strain ◽  
Rabbit Kidney ◽  
Rabbit Kidney Cell
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