Borrelia burgdorferi s.l., the Infectious Agent of Lyme Borreliosis

2001 ◽  
pp. 72-89 ◽  
Author(s):  
I. Diterich ◽  
T. Hartung
Keyword(s):  
Borrelia Burgdorferi ◽  
Lyme Borreliosis ◽  
Infectious Agent

scholarly journals Interactions between Borrelia burgdorferi and Mouse Fibroblasts

2010 ◽  
Vol 59 (3) ◽  
pp. 157-160 ◽  
Author(s):  
TOMASZ CHMIELEWSKI ◽  
STANISŁAWA TYLEWSKA-WIERZBANOWSKA
Keyword(s):  
Borrelia Burgdorferi ◽  
Lyme Borreliosis ◽  
Extracellular Space ◽  
Infectious Agent ◽  
Electron Microscopic ◽  
Mouse Fibroblasts ◽  
Microscopic Studies ◽  
Infected Cells ◽  
Fibroblastic Cells

Borrelia burgdorferi spirochetes are an infectious agent of Lyme borreliosis. The aim of our studies was to investigate the fate of engulfed B. burgdorferi cells in L-929 mouse fibroblasts and to observe development of intracellular infection in vitro after 2 and 48 h. Electron microscopic studies reveal consecutive stages of B. burgdorferi spirochetes penetration to mouse fibroblasts in vitro. It has been observed, as a first step attachment and engulfment of spirochetes followed by formation of vacuoles. After 48 hours of infection, vacuoles of fibroblastic cells have been seen full of B. burgdorferi bacteria and latter they have been released from infected cells to extracellular space. It can be the evidence that B. burgdorferi multiply intracellulary.

scholarly journals Imbalanced presence of Borrelia burgdorferi s.l. multilocus sequence types in clinical manifestations of Lyme borreliosis

2016 ◽  
Vol 42 ◽  
pp. 66-76 ◽  
Author(s):  
E. Claudia Coipan ◽  
Setareh Jahfari ◽  
Manoj Fonville ◽  
G. Anneke Oei ◽  
Lodewijk Spanjaard ◽  
...  
Keyword(s):  
Borrelia Burgdorferi ◽  
Lyme Borreliosis ◽  
Clinical Manifestations ◽  
Borrelia Burgdorferi S.L ◽  
Sequence Types

scholarly journals Questionnaire Surveys of Cases of Tick Bite and Lyme Borreliosis in Hunters in Hokkaido with Reference to Detection of Anti-Borrelia burgdorferi Antibody.

1992 ◽  
Vol 31 (10) ◽  
pp. 1163-1168 ◽  
Author(s):  
Nobuhiko KUBO ◽  
Yasutomo ARASHIMA ◽  
Minori YOSHIDA ◽  
Masato KAWABATA ◽  
Susumu NISHINARITA ◽  
...  
Keyword(s):  
Borrelia Burgdorferi ◽  
Lyme Borreliosis ◽  
Tick Bite ◽  
Questionnaire Surveys

scholarly journals Borrelia burgdorferi elongation factor EF-Tu is an immunogenic protein during Lyme borreliosis

2015 ◽  
Vol 4 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Sebastian E Carrasco ◽  
Youyun Yang ◽  
Bryan Troxell ◽  
Xiuli Yang ◽  
Utpal Pal ◽  
...  
Keyword(s):  
Borrelia Burgdorferi ◽  
Lyme Borreliosis ◽  
Elongation Factor ◽  
Immunogenic Protein

Association of Borrelia afzelii with rodents in Europe

Parasitology ◽  
2003 ◽  
Vol 126 (1) ◽  
pp. 11-20 ◽  
Author(s):  
K. HANINCOVÁ ◽  
S. M. SCHÄFER ◽  
S. ETTI ◽  
H.-S. SEWELL ◽  
V. TARAGELOVÁ ◽  
...  
Keyword(s):  
Borrelia Burgdorferi ◽  
Lyme Borreliosis ◽  
Tick Infestation ◽  
Zoonotic Transmission ◽  
Host Association ◽  
Borrelia Afzelii ◽  
Hard Ticks ◽  
Bank Voles ◽  
Endemic Focus ◽  
Questing Ticks

Borrelia burgdorferi sensu lato (s.l.) is maintained in nature by complex zoonotic transmission cycles, involving a large variety of vertebrates as hosts and hard ticks of the genus Ixodes as vectors. Recent studies suggest that the genospecies of B. burgdorferi s.l. and sometimes their subtypes are propagated by different spectra of hosts, mainly birds and rodents. In order to test the concept of host-association, we analysed the relationships between Borrelia genospecies, rodent hosts and I. ricinus ticks in an endemic focus of Lyme borreliosis in western Slovakia. Rodents and questing ticks were collected at a forested lowland locality near Bratislava. Tick infestation levels on rodents were determined, and spirochaete infections in ticks and in ear punch biopsies were analysed by PCR followed by genotyping. Mice were more heavily infested with ticks than bank voles, and a higher proportion of mice was infected with spirochaetes than voles. However, the infectivity of voles was much higher than that of mice. The vast majority of infections detected in the skin and in ticks feeding on the rodents represented B. afzelii. In contrast, more than half of all infections in questing ticks collected in the same region of Slovakia were identified as B. valaisiana and B. garinii. In conclusion, whilst the study reveals that mice and voles play different quantitative roles in the ecology of Lyme borreliosis, it demonstrates that B. afzelii is specifically maintained by European rodents, validating the concept of host-association of B. burgdorferi s.l.

Borrelia burgdorferi in a newborn despite oral penicillin for Lyme borreliosis during pregnancy

1988 ◽  
Vol 7 (4) ◽  
pp. 286-288 ◽  
Author(s):  
KLAUS WEBER ◽  
HANS-JÜRGEN BRATZKE ◽  
UWE NEUBERT ◽  
BETTINA WILSKE ◽  
PAUL HARRISON DURAY
Keyword(s):  
Borrelia Burgdorferi ◽  
Lyme Borreliosis ◽  
Oral Penicillin
Sign in / Sign up

Export Citation Format

Share Document