Impaired Water Excretion in a Hyponatremic Patient following Thyroidectomy: Causal Role of Glucocorticoid Deficiency

1998 ◽  
Vol 24 (5) ◽  
pp. 341-347
Author(s):  
Katsuhiko Yonemura ◽  
Ryuichi Furuya ◽  
Yutaka Oki ◽  
Hideki Matsushima ◽  
Kazuhisa Ohishi ◽  
...  
Keyword(s):  
Causal Role ◽  
Water Excretion ◽  
Glucocorticoid Deficiency ◽  
Impaired Water

scholarly journals Role of vasopressin in the impaired water excretion of glucocorticoid deficiency

1980 ◽  
Vol 18 (1) ◽  
pp. 58-67 ◽  
Author(s):  
Stuart L. Linas ◽  
Tomas Berl ◽  
Gary L. Robertson ◽  
Gary A. Aisenbrey ◽  
Robert W. Schrier ◽  
...  
Keyword(s):  
Water Excretion ◽  
Glucocorticoid Deficiency ◽  
Impaired Water

scholarly journals Role of Plasma Vasopressin in Impaired Water Excretion of Glucocorticoid Deficiency

1978 ◽  
Vol 62 (4) ◽  
pp. 738-744 ◽  
Author(s):  
John Boykin ◽  
Antoine Detorrenté ◽  
Abby Erickson ◽  
Gary Robertson ◽  
Robert W. Schrier
Keyword(s):  
Water Excretion ◽  
Plasma Vasopressin ◽  
Glucocorticoid Deficiency ◽  
Impaired Water

Vasopressin-dependent upregulation of aquaporin-2 gene expression in glucocorticoid-deficient rats

2000 ◽  
Vol 279 (3) ◽  
pp. F502-F508 ◽  
Author(s):  
Takako Saito ◽  
San-E Ishikawa ◽  
Fumiko Ando ◽  
Minori Higashiyama ◽  
Shoichiro Nagasaka ◽  
...  
Keyword(s):  
Gene Expression ◽  
Load Test ◽  
Sprague Dawley ◽  
Water Excretion ◽  
Water Load ◽  
Aquaporin 2 ◽  
Sprague Dawley Rats ◽  
Glucocorticoid Deficiency ◽  
Aqp2 Gene ◽  
Impaired Water

We determined alterations in renal aquaporin-2 (AQP2) gene expression in association with impaired water excretion in glucocorticoid-deficient rats. After adrenalectomy, Sprague-Dawley rats were administered aldosterone alone by osmotic pumps (glucocorticoid-deficient rats). As a control, both aldosterone and dexamethasone were administered. These animals were subjected to the studies on days 7–14. The expressions of AQP2 mRNA and protein in kidney of the glucocorticoid-deficient rats were increased by 1.6- and 1.4-fold compared with the control rats, respectively. An acute oral water load test verified the marked impairment in water excretion in the glucocorticoid-deficient rats. One hour after the water load, the expressions of AQP2 mRNA and protein were significantly reduced in the control rats, but they remained unchanged in the glucocorticoid-deficient rats. However, there was no alteration in [3H]arginine vasopressin (AVP) receptor binding and AVP V2 receptor mRNA expression in the glucocorticoid-deficient rats. A V2-receptor antagonist abolished the increased expressions of AQP2 mRNA and protein in the glucocorticoid-deficient rats. These results indicate that augmented expression of AQP2 participates in impaired water excretion, dependent on AVP, in glucocorticoid deficiency.

The role of vasopressin in the impaired water excretion of myxedema

1978 ◽  
Vol 64 (4) ◽  
pp. 613-621 ◽  
Author(s):  
W.Ronald Skowsky ◽  
Thomas A. Kikuchi
Keyword(s):  
Water Excretion ◽  
Impaired Water

Pathological Role of Aquaporin-2 in Impaired Water Excretion and Hyponatremia

2004 ◽  
Vol 16 (4) ◽  
pp. 293-296 ◽  
Author(s):  
S. Ishikawa ◽  
T. Saito ◽  
K. Kasono
Keyword(s):  
Water Excretion ◽  
Aquaporin 2 ◽  
Impaired Water

scholarly journals Role of vasopressin in impaired water excretion in conscious rats with experimental cirrhosis

1981 ◽  
Vol 20 (2) ◽  
pp. 173-180 ◽  
Author(s):  
Stuart L. Linas ◽  
Robert J. Anderson ◽  
Stephen J. Guggenheim ◽  
Gary L. Robertson ◽  
Tomas Berl ◽  
...  
Keyword(s):  
Experimental Cirrhosis ◽  
Water Excretion ◽  
Conscious Rats ◽  
Impaired Water

scholarly journals Role of plasma arginine vasopressin in the impaired water diuresis of isolated glucocorticoid deficiency in the rat

1980 ◽  
Vol 17 (2) ◽  
pp. 186-195 ◽  
Author(s):  
Ira N. Mandell ◽  
Ralph A. DeFronzo ◽  
Gary L. Robertson ◽  
John N. Forrest
Keyword(s):  
Arginine Vasopressin ◽  
Water Diuresis ◽  
Plasma Arginine ◽  
Glucocorticoid Deficiency ◽  
Impaired Water
Sign in / Sign up

Export Citation Format

Share Document