scholarly journals Association Study of Suicidal Behavior and Affective Disorders with a Genetic Polymorphism in ABCG1, a Positional Candidate on Chromosome 21q22.3

2000 ◽  
Vol 42 (1) ◽  
pp. 22-25 ◽  
Author(s):  
D. Rujescu ◽  
I. Giegling ◽  
N. Dahmen ◽  
A. Szegedi ◽  
I. Anghelescu ◽  
...  
Keyword(s):  
Genetic Polymorphism ◽  
Association Study ◽  
Suicidal Behavior ◽  
Affective Disorders ◽  
Positional Candidate

Association Study of a Brain-Derived Neurotrophic-Factor Genetic Polymorphism and Mood Disorders, Age of Onset and Suicidal Behavior

2003 ◽  
Vol 48 (4) ◽  
pp. 186-189 ◽  
Author(s):  
Chen-Jee Hong ◽  
Sheue-Jane Huo ◽  
Feng-Chang Yen ◽  
Chun-Liang Tung ◽  
Guo-Mei Pan ◽  
...  
Keyword(s):  
Genetic Polymorphism ◽  
Association Study ◽  
Mood Disorders ◽  
Suicidal Behavior ◽  
Neurotrophic Factor ◽  
Age Of Onset ◽  
Brain Derived Neurotrophic Factor

scholarly journals Can Anhedonia Be Considered a Suicide Risk Factor? A Review of the Literature

Medicina ◽  
2019 ◽  
Vol 55 (8) ◽  
pp. 458 ◽  
Author(s):  
Bonanni ◽  
Gualtieri ◽  
Lester ◽  
Falcone ◽  
Nardella ◽  
...  
Keyword(s):  
Suicidal Behavior ◽  
Affective Disorders ◽  
Suicide Attempts ◽  
Positive Association ◽  
Negative Association ◽  
Schizophrenia Spectrum Disorders ◽  
Post Traumatic Stress ◽  
Significant Positive Association ◽  
Search Terms ◽  
Schizophrenia Spectrum

Background and Objectives: At present, data collected from the literature about suicide and anhedonia are controversial. Some studies have shown that low levels of anhedonia are associated with serious suicide attempts and death by suicide, while other studies have shown that high levels of anhedonia are associated with suicide. Materials and Methods: For this review, we searched PubMed, Medline, and ScienceDirect for clinical studies published from 1 January 1990 to 31 December 2018 with the following search terms used in the title or in the abstract: “anhedonia AND suicid*.” We obtained a total of 155 articles; 133 items were excluded using specific exclusion criteria, the remaining 22 articles included were divided into six groups based on the psychiatric diagnosis: mood disorders, schizophrenia spectrum disorders, post-traumatic stress disorder (PTSD), other diagnoses, attempted suicides, and others (healthy subjects). Results: The results of this review reveal inconsistencies. Some studies reported that high anhedonia scores were associated with suicidal behavior (regardless of the diagnosis), while other studies found that low anhedonia scores were associated with suicidal behavior, and a few studies reported no association. The most consistent association between anhedonia and suicidal behavior was found for affective disorders (7 of 7 studies reported a significant positive association) and for PTSD (3 of 3 studies reported a positive association). In the two studies of patients with schizophrenia, one found no association, and one found a negative association. For patients who attempted suicide (undiagnosed), one study found a positive association, one a positive association only for depressed attempters, and one a negative association. Conclusions: We found the most consistent positive association for patients with affective disorders and PTSD, indicating that the assessment of anhedonia may be useful in the evaluation of suicidal risk.

Tryptophan hydroxylase polymorphism and suicidality in unipolar and bipolar affective disorders: a multicenter association study

2001 ◽  
Vol 49 (5) ◽  
pp. 405-409 ◽  
Author(s):  
Daniel Souery ◽  
Sophie Van Gestel ◽  
Isabelle Massat ◽  
Sylvie Blairy ◽  
Rolf Adolfsson ◽  
...  
Keyword(s):  
Association Study ◽  
Affective Disorders ◽  
Tryptophan Hydroxylase ◽  
Bipolar Affective Disorders

Role of serotonergic-related systems in suicidal behavior: Data from a case–control association study

2011 ◽  
Vol 35 (6) ◽  
pp. 1518-1524 ◽  
Author(s):  
Pilar A. Saiz ◽  
Paz García-Portilla ◽  
Begoña Paredes ◽  
Paul Corcoran ◽  
Celso Arango ◽  
...  
Keyword(s):  
Association Study ◽  
Suicidal Behavior ◽  
Case Control ◽  
Control Association

scholarly journals Whole-genome association study searching for QTL for Aeromonas salmonicida resistance in rainbow trout

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Moonika H. Marana ◽  
Asma M. Karami ◽  
Jørgen Ødegård ◽  
Shaozhi Zuo ◽  
Rzgar M. Jaafar ◽  
...  
Keyword(s):  
Rainbow Trout ◽  
Association Study ◽  
Genome Wide Association Study ◽  
Snp Array ◽  
Disease Outbreaks ◽  
Significant Snps ◽  
Aeromonas Salmonicida ◽  
Natural Resistance ◽  
Positional Candidate ◽  
Time To Death

AbstractAeromonas salmonicida subsp. salmonicida, the causative agent of furunculosis, has extensive negative effects on wild and farmed salmonids worldwide. Vaccination induces some protection under certain conditions but disease outbreaks occur even in vaccinated fish. Therefore, alternative disease control approaches are required to ensure the sustainable expansion of rainbow trout aquaculture. Selective breeding can be applied to enhance host resistance to pathogens. The present work used genome-wide association study (GWAS) to identify quantitative trait loci (QTL) associated with A. salmonicida resistance in rainbow trout. A total 798 rainbow trout exposed to A. salmonicida by bath challenge revealed 614 susceptible and 138 resistant fish. Genotyping was conducted using the 57 K single nucleotide polymorphism (SNP) array and the GWAS was performed for survival and time to death phenotypes. We identified a QTL on chromosome 16 and located positional candidate genes in the proximity of the most significant SNPs. In addition, samples from exposed fish were examined for expression of 24 immune-relevant genes indicating a systematic immune response to the infection. The present work demonstrated that resistance to A. salmonicida is moderately heritable with oligogenic architecture. These result will be useful for the future breeding programs for improving the natural resistance of rainbow trout against furunculosis.

AN ASSOCIATION STUDY BETWEEN SUICIDAL BEHAVIOR AND TRYPTOPHAN HYDROXYLASE DNA MARKERS

1991 ◽  
Vol 2 (1) ◽  
pp. 105-106
Author(s):  
M. Abbar ◽  
Schenk ◽  
A. Malaforsse ◽  
S. Anadeo ◽  
J. Mallet ◽  
...  
Keyword(s):  
Association Study ◽  
Suicidal Behavior ◽  
Dna Markers ◽  
Tryptophan Hydroxylase
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