Introduction of a Central Documentation of Blood Products according to §§ 14 and 17 Transfusionsgesetz (TFG) by a Computerized Blood Bank Data System

2001 ◽  
Vol 28 (1) ◽  
pp. 20-23 ◽  
Author(s):  
G. Hutschenreuter ◽  
M. Kiese ◽  
M. Wessiepe
Keyword(s):  
Blood Bank ◽  
Data System ◽  
Blood Products

scholarly journals Bacterial Contamination of Blood and Blood Products at Mbarara Regional Blood Bank in Rural South Western Uganda

2013 ◽  
Vol 03 (03) ◽  
pp. 205-209 ◽  
Author(s):  
G. B. Matte Aloysius ◽  
Bazira Joel ◽  
Richard Apecu ◽  
Boum Yap II ◽  
Frederick Byarugaba
Keyword(s):  
Bacterial Contamination ◽  
Blood Bank ◽  
Blood Products ◽  
Rural South ◽  
Western Uganda

Logistics of Massive Transfusions

Hematology ◽  
2010 ◽  
Vol 2010 (1) ◽  
pp. 470-473 ◽  
Author(s):  
Thomas G. DeLoughery
Keyword(s):  
Emergency Department ◽  
Massive Bleeding ◽  
Blood Bank ◽  
Trauma Patients ◽  
Blood Products ◽  
Proper Management ◽  
Surgical Suite

Abstract Care of the patient with massive bleeding involves more than aggressive surgery and infusion of large amounts of blood products. The proper management of massive transfusions—whether they are in trauma patients or other bleeding patients—requires coordination of the personnel in the surgical suite or the emergency department, the blood bank, and laboratory.

Disaster Impact (11-M) in a Blood Bank.

Blood ◽  
2004 ◽  
Vol 104 (11) ◽  
pp. 2707-2707
Author(s):  
Natalia Hernandez de Leon ◽  
Javier Anguita ◽  
Carmen Falero ◽  
Almudena Llorente ◽  
Tomas Pintado Cros ◽  
...  
Keyword(s):  
Surgical Procedures ◽  
Blood Donation ◽  
Terrorist Attack ◽  
Blood Bank ◽  
Blood Products ◽  
Patient Identification ◽  
Major Disaster ◽  
Short Period ◽  
Group A ◽  
Group B

Abstract Objective: To describe the main problems posed to a hospital’s blood bank (BB) by a major disaster situation (the11-M terrorist attack in Madrid, Spain). Report of the events: In the terrorist attack of Madrid in March 11, 2004, there were a total of 192 casualties and 1432 individuals who suffered various, usually complex, injuries. At the Gregorio Marañon Hospital 232 victims of the attack were admitted and 32 of them required surgical procedures. On this day there were 122 requests for blood products for 23 patient. Transfusion issues: Patient identification: initially most of transfusion requests arrived without patient’s demographic data nor blood sample; a numeric code was assigned to each case. Blood group testing: only ABO-type and Rh-D antigen were determined. Transfusion policy: patients were transfused with same specific ABO group whenever possible, otherwise with ABO compatible uncrossmatched red blood cells (RBC); for this purpose, retyped group A and O RBC were stored separately. Rh-D negative units were reserved for young D-negative females. Blood donation issues: There was a massive arrival of volunteers to donate blood in a very short period of time, which completely collapsed the BB facilities. It was necessary to improvise for additional space as well as technical staff and paramedical personal to attend to the massive flux of overanxious volunteers. Regular blood donors were rejected in order to guarantee blood supply after the catastrophe. Many volunteers could not donate at the time and a telephone number and address were obtained for recall at a later time if needed. Table I shows the results of HbsAg and HVC testing of blood donated on the day of the catastrophe (group B) compared with donors before the 11-M (group A). Conclusions: At a major public disaster such as the 11-M terrorist attack, donation greatly exceeds the actual needs generated by the catastrophe. Furthermore, this donation is of no use for the immediate needs. Ideally, civil authorities should not encourage blood donation indiscriminately but alert the general population to do so only after an evaluation of available resources and estimated needs. A center’s contingency plan should include: coordination with local authorities and regional blood center; hospital heads and directors should cancel all programmed activities, in particular surgical procedures and divert human effort resources to emergency care of the injured; the BB should reorganize its activities, initially focusing in patient identification and testing, redistribution and retyping of available blood products in order to deliver quickly type specific RBC; after above goals have been met, staff resources should be redistributed for blood collection and processing. Table I: Blood testing results an donation data. Total donors First-time donors Repeat donors Number HBsAg+ / VHC+ Number HBsAg+ / VHC+ Number HBsAg+ / VHC+ Between March 11 and March 14, 633 donations were made, 398 on March 11; this represent a 1,658% increment from the usual mean. There was a higher % of HCV positivity in group B compared to regular donors and no difference in HBV and HIV testing between both groups. A 662 2 / 2 323 1 / 2 339 1 / 0 B 633 1 / 5 543 1 / 5 90 0 / 0 Table II:Transfusion data. Available RCC Hospitalized Deceased Surgery Previous stock Received the 11-M Transfused 1st 4h Total transfused the 11-M During the first 4 hours 82% of the transfused patients (19) were registered at the blood bank and 63% of the RBC used that day (90 units) were transfused. 71,72% of RBC were specific ABO-group. 232 4 36 149 265 90 (62%) 143

scholarly journals Profile of Blood Donor Deferrals in a Tertiary Care Centre-Our Institutional Experience

2021 ◽  
pp. 75-80
Author(s):  
D. Rajeswari Thivya ◽  
R. Vijayashree ◽  
K. Meghanath
Keyword(s):  
Blood Donor ◽  
Demographic Data ◽  
Tertiary Care ◽  
Blood Bank ◽  
Care Hospital ◽  
Blood Products ◽  
Tertiary Care Centre ◽  
Donor Pool ◽  
Common Cause ◽  
Donor Deferral

Background:  It is the prime duty of transfusion services to provide safe, adequate and timely need of blood and the blood products. Understanding the reasons for donor deferral can help in planning more efficient recruitment strategies and educate and motivate temporarily deferred donors in order to maintain a safe and adequate supply of blood products. Aims of the Study: To evaluate and analyze the blood donor deferral pattern in a tertiary care hospital blood bank and to review its influence on blood safety. Methodology: This retrospective study was conducted in the blood bank, CHRI from the year January 2015 to December 2018. Data like demographic data, clinical history, physical examination, haematological examination, stored in the blood bank was retrived. The donors will be deferred based on standard WHO guidelines. The collected deferral data was analyzed using SPSS software 2011version 20. Results: During the study period there were 7010 registered blood donors. The deferral rate was 5.19%. Among the donor deferrals, females were more commonly deferred ie 31.66%. The deferral rate among voluntary and replacement donors are 4.71% and 11.62% respectively. The rate of permanent deferral (17.86%) was less compared to temporary deferral (82.14%). Among temporary deferral anaemia is the most common cause (27.75%). Seropositive for Hepatitis B is the most common cause for permenant deferral (52.30%). Conclusion: In our study temporary deferral is higher this necessities the need of education, motivation of these donors for future donation to maintain a healthy and safe donor pool. 

scholarly journals BLOOD BANK SCENARIO DURING COVID 19 PANDEMIC- EXPERIENCE FROM TERTIARY CARE HOSPITAL

2020 ◽  
pp. 1-3
Author(s):  
Sandhya V Poflee ◽  
Archana L Khade ◽  
Sanjay N Parate ◽  
Dinkar T Kumbhalkar
Keyword(s):  
Blood Donation ◽  
Statistical Significance ◽  
Tertiary Care ◽  
Transmitted Disease ◽  
Blood Bank ◽  
World Health ◽  
Blood Collection ◽  
Care Hospital ◽  
Blood Products ◽  
Significant Difference

Background: From initial declaration of outbreak of Severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) infections in December 2019 to declaration of pandemic on 11th March 2020 by World health organization (WHO), vast changes were noticed on healthcare scenario. Irrespective of projection in media, we observed specific changes only in some of the blood banking activities. Objectives: To evaluate changes in scenario at our blood bank during lockdown (restricted movements) period of COVID 19 pandemic. To get insight into the causation of the changes was the aim of this study. Material and Methods: Number of blood units collected, blood and blood products issued in parallel months of 2019 and 2020 were compared. Voluntary blood donation (VBD) activities carried out during lockdown period were also scrutinized, during respective months. Blood bank data was analyzed and statistical significance and correlation was evaluated. Results: Statistically significant increase was observed in utilization blood and blood products and collection from VBD camps in the months of March to May 2020, when compared with the respective months of year 2019.Major blood collection during March to May 2020 was from voluntary blood donation camps organized in rural areas. No significant difference was found in transfusion transmitted disease (TTD) positivity of blood unit collected during parallel months of 2019 and 2020. Conclusion: Even with COVID 19 pandemic, routine blood bank activities in our blood bank were not adversely affected. This was possible with timely guidelines from the concerned authorities, administrative support and proper mobilization of available resources during this period.

scholarly journals Erythrocyte Phenotyping in ABO, RH and Kell Blood Group Systems in the Donor and Recipient of Blood Products at the Yaounde University and Hospital Center

2020 ◽  
pp. 31-37
Author(s):  
B. Chetcha Chemegni ◽  
A. Ndoumba ◽  
Jiatsa Bogning ◽  
E. Lontsi ◽  
C. Tayou Tagne ◽  
...  
Keyword(s):  
Blood Group ◽  
Blood Bank ◽  
University Hospital ◽  
Blood Group System ◽  
Average Risk ◽  
Blood Products ◽  
Compatible Blood ◽  
D Antigen ◽  
The University ◽  
Hospital Center

In order to prevent post transfusion alloimmunization, it is essential to give recipients compatible blood products. However in countries with limited income, blood grouping is limited to the ABO system and to the D antigen of the Rhesus system; however, there are other immunogenic antigens such as C, c, E, e and K to name a few. This should be the reason why a retrospective study by Tayou et al. at the blood bank of the University Hospital Center (CHU) of Yaoundé in 2009 on the erythrocyte phenotype in the donor and recipient of blood product only reported to us that data relate to the erythrocyte blood group system ABO and the Rh 1 antigen. We therefore found it expedient to carry out erythrocyte phenotyping in the ABO, RH and KELL blood group systems in the donor and recipient of blood products at the CHU of Yaoundé. A descriptive, transversal and prospective study was carried out at the blood bank of the CHU of Yaoundé over 6 months, from June 1, 2017 to December 31, 2017. It was interested in the donor-recipient couples of blood within which the recipient was a patient hospitalized at the CHU. Laboratory analyses of donor and recipient blood samples have allowed us to have the phenotypes in the ABO, RH, and KELL blood group systems. In the ABO system, the phenotypes obtained were 4: A1, A1B, B and O at 27.27%, 2.27%, 13.64% and 56.82% respectively among donors and 31.82%, 2.27%, 13.64% and 52.27% among recipients. In addition, from the Rhesus system, there were 5 phenotypes in donors: D + C + E + c + e +, D + C + E-c + e +, D + C-E + c + e +, D + CE-c + e +, DCE-c + e + respectively at 2.27%, 11.36%, 9.09%, 75.00% and 2.27% and in recipients 4 phenotypes, namely: D + C + E + c + e +, D + C-E + c + e +, D + CE-c + e +, DCE-c + e + at 15.91%, 27.27%, 54.55% and 2.27% respectively. In the KELL system, the K antigen was present in 4.55% of donors and 2.27% of recipients. An antigen supply from the donor to the recipient was evaluated at 6.82% for C, 4.54% for E, 2.27% for K and 2.27% for K, C, E at the same time. This gave us an estimate of the average risk of alloimmunization at 15.9%. Erythrocyte phenotyping would therefore be of major benefit during blood transfusion and would considerably prevent the risks of alloimmunization.

scholarly journals FRESH FROZEN PLASMA

2018 ◽  
Vol 25 (09) ◽  
pp. 1364-1368
Author(s):  
Muhammad Asim Khan ◽  
Maryam Alam Khan ◽  
Aneela Dar ◽  
Syed Asad Maroof ◽  
Mohammad Zarin ◽  
...  
Keyword(s):  
General Medicine ◽  
Fresh Frozen Plasma ◽  
Infectious Complications ◽  
Blood Bank ◽  
Blood Products ◽  
Sampling Errors ◽  
Cross Sectional ◽  
Gynecology And Obstetrics ◽  
Fresh Frozen ◽  
Frozen Plasma

Introduction: As the use of Fresh Frozen Plasma (FFP) is having establishedcomplications including Allergic reactions, infectious complications, hemolysis, fluid overload, transfusion related acute lung injury (TRALI) and immune suppression, therefore it mustbe used cautiously. Objectives: To evaluate the inappropriate use of FFPs, to carry out anaudit of appropriateness of FFP transfusion with reference to international guidelines and setfoundations for blood bank and transfusion protocols. Study Design: Cross sectional study.Setting: Khyber Teaching Hospital Peshawar. Period: 6 months, 1st January 2016 to 30th June2016. Methods: During which FFP transfusion requests made to the blood bank by various unitsof the hospital were studied including general surgery, surgical ICU, general medicine, medicalICU, gynecology and obstetrics. Seventy Six requests were received that were judged using6 variables: indication for FFP use, sampling errors, laboratory analysis errors, interpretationerrors, dosage of FFP (number of units being transfused) and timing of FFP transfusion. Scoreof “1” was given for each correct variable. After matching data to the international protocols, ascore of 4-5 was taken as appropriate and <3 was classified as inappropriate. Results: TwentySeven (35.5%) FFP transfusions were done with a score of 4-5 and were considered appropriatewhile 49(64.5%) FFP transfusions were given a score of 3 or less and were consideredinappropriate. Conclusions: Almost two third of FFP were used inappropriately in our hospital,the commonest indication being acute Disseminated Intravascular Coagulation (DIC) andmostly requested from surgical units. Maximum cases of inappropriate transfusions were dueto wrong sampling techniques and wrong dosage calculations. Most inappropriate transfusionswere done in MICU. It is recommended that annual clinical audit of all blood products usageshould be conducted. Local guidelines for physicians and training programs for nurses andparamedics regarding proper use of blood products should be established.

Effective Reduction of Blood Product Use In a Community Teaching Hospital: a Possible Interventional Model.

Blood ◽  
2010 ◽  
Vol 116 (21) ◽  
pp. 1126-1126
Author(s):  
Alex Politsmakher ◽  
Dipanita Barua ◽  
Harvey Dosik
Keyword(s):  
Hospital Admissions ◽  
Conflicts Of Interest ◽  
Physician Behavior ◽  
Clinical Situation ◽  
Fresh Frozen Plasma ◽  
Blood Bank ◽  
Easy Access ◽  
Blood Products ◽  
Fresh Frozen ◽  
Frozen Plasma

Abstract Abstract 1126 Background: The complications of blood transfusions and the increased morbidity and mortality associated with liberal use of blood products have been convincingly demonstrated. The clinical problems they pose have prompted development of evidence-based transfusion guidelines. Nevertheless, most hospitals do not enforce these guidelines and effective strategies have not been developed. Continuing medical education, such as conferences, do not appear to be effective in changing physician behavior, as confirmed in the literature and by our hospital's experience. New York Methodist Hospital therefore undertook a more proactive approach to reduce unnecessary transfusions and in the process to change physicians' attitude toward transfusions. Methods: In October 2008, our hospital implemented strict criteria for transfusions of all blood products including red blood cells (RBC), platelets, fresh frozen plasma, and cryoprecipitate. These criteria were applied by selected experienced clinicians who each served as monitors for their own clinical department. The blood bank required the approval of the monitor to release blood products that did not meet the criteria. This helped ensure that patients who indeed require transfusion based on clinical situation would be treated appropriately. Physicians had easy access to the monitors 24 hours a day, 365 days a year. Transfusion requests from operating rooms and post-anesthesia care units were excluded from monitoring. Transfusion of patients with active bleeding was also exempted because it was included in the RBC justification criteria. In most patients with symptomatic anemia, a single unit of RBC was approved. We compared data from the 12 months preceding (Year 1) and the 12 months after the enforcement of the criteria (Year 2). The data included the number of hospital admissions, the amount of blood products transfused per month, the type and number of transfusion-related complications, and the number of type and screens performed by the blood bank. Results: Transfusion usage declined sharply from Year 1 to Year 2: RBC use fell by 27.9% (9,149 vs. 6,599 units), fresh frozen plasma use fell by 40.3 % (3,615 vs. 2,158), platelets use fell by 22.1 % (1,207 vs. 940), and cryoprecipitate use fell by 37.4% (1,421 vs. 890). These decreases occurred in the face of a 2.9% increase in hospital admissions over 12 months (from 35,348 to 36,421). The decreased transfusion use was accompanied by reduced complications, which declined by 28.6 % (35 transfusion reactions in Year 1 vs. 25 in Year 2). The total cost of blood products declined by $1,027,869 (from $3,694,069 in Year 1 to $2,666,200 in Year 2). The number of type and screen tests requested and performed in the hospital also decreased by 6.3% (from 28,488 in Year 1 to 26,681 in Year 2). Conclusion: We report our one-year experience with a new model for improving transfusion use. Monitoring and intervention in described settings with possibilities of appeal reduced transfusion use by 22–40%. It also appeared to modify physician attitude as exemplified by a 6.3% reduction in type and screen requests in spite of 2.9% increase in admissions. Although small, this decline supports the trend toward fewer transfusions and suggests a change in physician culture and behavior. We recommend other hospitals consider similar versions of this strategy appropriate for their circumstances since it benefits patients and reduces health care costs. Disclosures: No relevant conflicts of interest to declare.

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