Decreased Mitochondrial Oxygen Consumption and Antioxidant Enzyme Activities in Skeletal Muscle of Dystrophic Mice after Low-Intensity Exercise

2001 ◽  
Vol 45 (2) ◽  
pp. 58-66 ◽  
Author(s):  
V. Faist ◽  
J. König ◽  
H. Höger ◽  
I. Elmadfa
Keyword(s):  
Skeletal Muscle ◽  
Oxygen Consumption ◽  
Antioxidant Enzyme ◽  
Enzyme Activities ◽  
Antioxidant Enzyme Activities ◽  
Mitochondrial Oxygen Consumption ◽  
Low Intensity ◽  
Low Intensity Exercise ◽  
Dystrophic Mice

Pair-wise linear and 3D nonlinear relationships between the liver antioxidant enzyme activities and the rate of body oxygen consumption in mice

2002 ◽  
Vol 33 (12) ◽  
pp. 1736-1739 ◽  
Author(s):  
Khachik K Muradian ◽  
Natalie A Utko ◽  
Tatyana G Mozzhukhina ◽  
Alexander Y Litoshenko ◽  
Irina N Pishel ◽  
...  
Keyword(s):  
Oxygen Consumption ◽  
Antioxidant Enzyme ◽  
Enzyme Activities ◽  
Antioxidant Enzyme Activities ◽  
Nonlinear Relationships

Aging and exercise training in skeletal muscle: responses of glutathione and antioxidant enzyme systems

1994 ◽  
Vol 267 (2) ◽  
pp. R439-R445 ◽  
Author(s):  
C. Leeuwenburgh ◽  
R. Fiebig ◽  
R. Chandwaney ◽  
L. L. Ji
Keyword(s):  
Skeletal Muscle ◽  
Exercise Training ◽  
Antioxidant Enzyme ◽  
Enzyme Activities ◽  
Vastus Lateralis ◽  
Antioxidant Systems ◽  
Antioxidant Enzyme Activities ◽  
Vastus Lateralis Muscle ◽  
Adult Rats ◽  
Young Rats

Glutathione (GSH) content and antioxidant enzyme activities were investigated in skeletal muscle of young, adult, and old male Fischer 344 rats. Furthermore, the effect of 10 wk of exercise training on these antioxidant systems was evaluated at all ages. In the soleus muscle, GSH concentration increased markedly with age, with no significant change in glutathione disulfide (GSSG) content. Training caused a 30% decrease of GSH (P < 0.05) in the soleus of young rats and a reduction of the GSH-to-GSSG ratio at all ages. Activity of gamma-glutamyl transpeptidase (GGT), a key enzyme for GSH uptake by muscle, was also significantly decreased with training. GSH, GSSG, and the GSH-to-GSSG ratio were not altered with aging or training in the deep portion of vastus lateralis muscle (DVL). Activities of GSH peroxidase (GPX), GSSG reductase (GR), superoxide dismutase (SOD), catalase (CAT), and GSH sulfur-transferase were increased significantly with aging in both soleus and DVL. In DVL, training increased GPX and SOD activities in the young rats, whereas in soleus, training decreased GR and CAT activities in the adult rats and GGT and CAT activities in the old rats. Muscle lipid peroxidation was significantly increased with aging in both DVL and soleus but was not affected by training. These data indicate that aging may cause not only an overall elevation of antioxidant enzyme activities but also a fiber-specific adaptation of GSH system in skeletal muscle. Exercise training, although increasing selective antioxidant enzymes in the young rats, does not offer additional protection against oxidative stress in the senescent muscle.

Improving the activity of Lycium barbarum polysaccharide on sub-health mice

2015 ◽  
Vol 6 (6) ◽  
pp. 2033-2040 ◽  
Author(s):  
Rui Zhao ◽  
Yaping Cai ◽  
Xingyue Shao ◽  
Baoling Ma
Keyword(s):  
Skeletal Muscle ◽  
Lipid Peroxidation ◽  
Membrane Potential ◽  
Antioxidant Enzyme ◽  
Calcium Homeostasis ◽  
Enzyme Activities ◽  
Mitochondrial Membrane ◽  
Antioxidant Enzyme Activities ◽  
Lycium Barbarum ◽  
Lycium Barbarum Polysaccharide

Anti-fatigue activity of Lycium barbarum polysaccharide on sub-health mice: LBP-4a exhibited anti-fatigue activity on sub-health mice, and the mechanism was closely correlated with the reduction of lipid peroxidation levels and an increase of antioxidant enzyme activities in skeletal muscle tissue, in addition to the improvement in intracellular calcium homeostasis imbalance of skeletal muscle and an increase in mitochondrial membrane potential.

Antioxidant enzyme activities in heart and skeletal muscle of rats of different ages

1989 ◽  
Vol 24 (3) ◽  
pp. 211-218 ◽  
Author(s):  
Mario Vertechy ◽  
Michael B. Cooper ◽  
Orlando Ghirardi ◽  
M.Teresa Ramacci
Keyword(s):  
Skeletal Muscle ◽  
Antioxidant Enzyme ◽  
Enzyme Activities ◽  
Antioxidant Enzyme Activities ◽  
Different Ages
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