Assignment1 of the murine tumor susceptibility gene 101 (tsg101) and a processed tsg101 pseudogene (tsg101-ps1) to mouse chromosome 7 band B5 and chromosome 15 band D1 by in situ hybridization

1999 ◽  
Vol 84 (1-2) ◽  
pp. 87-88 ◽  
Author(s):  
K.-U. Wagner ◽  
P. Dierisseau ◽  
L. Hennighausen
Genome ◽  
1995 ◽  
Vol 38 (4) ◽  
pp. 780-785 ◽  
Author(s):  
S. Mai ◽  
J. Hanley-Hyde ◽  
A. Coleman ◽  
D. Siwarski ◽  
K. Huppi

After adaptation of a mouse plasma cell tumor, MOPC265, to culture, we have found several unique chromosomal alterations in addition to the T(12;15) translocation and trisomy 11 frequently observed in plasmacytomas. Among these alterations is a specific coamplification of the c-Myc and Pvt 1 gene loci from mouse chromosome 15. Further analysis by fluorescence in situ hybridization demonstrates that the amplicons of c-Myc and Pvt 1 exist as extrachromosomal elements as well as within intact chromosomes. Most importantly, the presence of both Pvt 1 and c-Myc in these extrachromosomal elements indicates ongoing coselection for these loci in the propagation of MOPC265.Key words: amplification, c-Myc, Pvt 1, plasmacytoma.


Cancer ◽  
2002 ◽  
Vol 96 (2) ◽  
pp. 105-109 ◽  
Author(s):  
Jonathan L. Hecht ◽  
Benjamin H. Lee ◽  
Jack L. Pinkus ◽  
Geraldine S. Pinkus

2000 ◽  
Vol 89 (3-4) ◽  
pp. 216-217
Author(s):  
C. Popovici ◽  
M.-G. Mattéi ◽  
J.B. Rattner ◽  
D. Birnbaum ◽  
M.-J. Pébusque

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