Prognostic Value of DNA Ploidy and Proliferating Cell Nuclear Antigen in Gastric Cancer

Oncology ◽  
1998 ◽  
Vol 55 (4) ◽  
pp. 300-306 ◽  
Author(s):  
Kazuo Hirose ◽  
Atsushi Iida ◽  
Akio Yamaguchi ◽  
Hidetoshi Onchi ◽  
Hirofumi Awata ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Proliferating Cell Nuclear Antigen ◽  
Prognostic Value ◽  
Dna Ploidy ◽  
Nuclear Antigen ◽  
Proliferating Cell

Prediction of Lymph Node Metastasis and Prognosis from the Assay of the Expression of Proliferating Cell Nuclear Antigen and DNA Ploidy in Gastric Cancer

Oncology ◽  
1994 ◽  
Vol 51 (3) ◽  
pp. 251-257 ◽  
Author(s):  
Yutaka Yonemura ◽  
Luis Fonseca ◽  
Kouichirou Tsugawa ◽  
Itasu Ninomiya ◽  
Hisashi Matsumoto ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Proliferating Cell Nuclear Antigen ◽  
Dna Ploidy ◽  
Nuclear Antigen ◽  
Node Metastasis ◽  
Proliferating Cell

Clinical relevance of p53 index and expression of proliferating cell nuclear antigen and Ki-67 in gastric cancer

1998 ◽  
Vol 124 (9) ◽  
pp. 497-502 ◽  
Author(s):  
Leena Setälä ◽  
Veli-Matti Kosma ◽  
Pertti Lipponen ◽  
Anita Naukkarinen ◽  
Stig Nordling ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Proliferating Cell Nuclear Antigen ◽  
Clinical Relevance ◽  
Nuclear Antigen ◽  
Ki 67 ◽  
Proliferating Cell

scholarly journals Phosphorylation of p53 Serine 15 Is a Predictor of Survival for Patients with Hepatocellular Carcinoma

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Taewoo Yang ◽  
Yegyun Choi ◽  
Jae Won Joh ◽  
Steve K. Cho ◽  
Dae-Shick Kim ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Proliferating Cell Nuclear Antigen ◽  
Prognostic Value ◽  
Nuclear Antigen ◽  
Survival Outcomes ◽  
P53 Expression ◽  
Immunohistochemical Markers ◽  
Prognostic Utility ◽  
Poor Outcomes ◽  
Proliferating Cell

Background. Hepatocellular carcinoma (HCC) is one of the most common malignant cancers with a poor prognosis. Several commonly investigated immunohistochemical markers in resected HCC have potential prognostic value, but the prognostic utility of p53 expression in HCC has remained elusive. Aim. To evaluate the prognostic value of p53 and p53 phosphorylation at serine 15 (p53 Ser15-P) in patients with HCC. Methods. Surgically resected tumors from 199 HCC patients were analyzed for p21, p53, p53 Ser15-P, and proliferating cell nuclear antigen (PCNA) expression using immunohistochemistry. Results. Stratifying by the expression of p53 Ser15-P (P = 0.016), but not by p53 (P = 0.301), revealed significantly different survival outcomes in patients with HCC. Moreover, our analysis demonstrated that patients who were PCNA-positive and p53 Ser15-P–negative had significantly worse survival outcomes (P = 0.001) than patients who were PCNA-positive and p53 Ser15-P–positive. Conclusions. P53 Ser15-P is associated with poor outcomes in patients with HCC, and this prognostic marker is useful for predicting the survival of patients with PCNA-positive HCC.

Prognostic value of proliferating cell nuclear antigen in parotid gland cancer

2011 ◽  
Vol 269 (4) ◽  
pp. 1225-1232 ◽  
Author(s):  
Markus Stenner ◽  
Ariane Demgensky ◽  
Christoph Molls ◽  
Aline Hardt ◽  
Jan C. Luers ◽  
...  
Keyword(s):  
Parotid Gland ◽  
Proliferating Cell Nuclear Antigen ◽  
Prognostic Value ◽  
Nuclear Antigen ◽  
Parotid Gland Cancer ◽  
Proliferating Cell
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