scholarly journals Copper (II) Acylhydrazinates. Their Synthesis and Characterization

2001 ◽  
Vol 8 (3) ◽  
pp. 171-177 ◽  
Author(s):  
Zahid H. Chohan ◽  
M. A. Farooq ◽  
Claudiu T. Supuran
Keyword(s):  
Escherichia Coli ◽  
Schiff Bases ◽  
Metal Ion ◽  
Bacterial Species ◽  
Analytical Data ◽  
Synthesis And Characterization ◽  
Tetradentate Ligand ◽  
Base Function ◽  
Enolic Form ◽  
Square Planar

Acylhydrazine derived furanyl and thienyl Schiff bases and their Cu(II) complexes have been prepared and characterized on the basis of their physical, spectral and analytical data. The preferred enolic form of the Schiff base function as a tetradentate ligand during coordination to the metal ion yielding a square planar complex. The Schiff bases and their complexes with different anions were tested for their antibacterial activity against bacterial species such as Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa andKlebsiella pneumonae.

scholarly journals Synthesis, Characterization and Biological Properties of Anions of Bivalent Transition Metal [Co(II) and Ni(II)] Complexes With Acylhydrazine Derived ONO Donor Schiff Bases

2000 ◽  
Vol 7 (3) ◽  
pp. 133-139 ◽  
Author(s):  
Zahid H. Chohan ◽  
M. A. Farooq ◽  
M. S. Iqbal
Keyword(s):  
Escherichia Coli ◽  
Schiff Bases ◽  
Metal Ion ◽  
Bacterial Species ◽  
Biological Properties ◽  
Molar Conductance ◽  
Schiff Base Ligands ◽  
Enolic Form ◽  
Elemental Analyses ◽  
Bivalent Transition Metal

Some acylhydrazine derived ONO donor Schiff bases and their Co(II) and Ni(II) complexes have been prepared having the same metal ion (cation) but different anions. These synthesized metal(II) complexes have been characterized on the basis of their elemental analyses, magnetic moment, molar conductance, and IR and electronic spectral data. All of the Schiff base ligands function as tridentates and the deprotonated enolic form is preferred for coordination. In order to evaluate the effect of anions on the bactericidal activity, these synthesized complexes, in comparison to the uncomplexed Schiff bases have been screened against bacterial species., Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa and the results are reported.

scholarly journals Transition Metal Ion Complexes of Schiff-bases. Synthesis, Characterization and Antibacterial Properties

2001 ◽  
Vol 8 (3) ◽  
pp. 137-143 ◽  
Author(s):  
Zahid H. Chohan ◽  
Asifa Munawar ◽  
Claudiu T. Supuran
Keyword(s):  
Escherichia Coli ◽  
Transition Metal ◽  
Schiff Bases ◽  
Metal Ion ◽  
Bacterial Species ◽  
Analytical Data ◽  
Antibacterial Properties ◽  
Octahedral Geometry ◽  
Complexation Reaction ◽  
New Compounds

Some novel transition metal [Co(II), Cu(II), Ni(II) and Zn(II)] complexes of substituted pyridine Schiff-bases have been prepared and characterized by physical, spectral and analytical data. The synthesized Schiff-bases act as deprotonated tridentate for the complexation reaction with Co(II), Ni(II) and Zn(II) ions. The new compounds, possessing the general formula [M(L)2] where [M=Co(II), Cu(II), Ni(II) and Zn(II) and HL=HL1, HL2, HL3 and HL4] show an octahedral geometry. In order to evaluate the effect of metal ions upon chelation, the Schiff bases and their complexes have been screened for antibacterial activity against the strains such as Escherichia coli,Staphylococcus aureus, and Pseudomonas aeruginosa. The complexed Schiff bases have shown to be more antibacterial against one more bacterial species as compared to uncomplexed Schiff-bases.

scholarly journals Antibacterial Co(II), Cu(II), Ni(II) and Zn(II) Complexes of Thiadiazoles Schiff Bases

2001 ◽  
Vol 8 (2) ◽  
pp. 95-101 ◽  
Author(s):  
Zahid H. Chohan ◽  
Maimoon F. Jaffery ◽  
Claudiu T. Supuran
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Schiff Bases ◽  
Bacterial Species ◽  
Analytical Data ◽  
Bacterial Strains ◽  
Antibiotic Resistant ◽  
Resistant Strains ◽  
New Compounds

Schiff bases were obtained by condensation of 2-amino-l,3,4-thiadiazole with 5-substituted-salicylaldehydes which were further used to obtain complexes of the type [M(L)2]Cl2, where M=Co(II), Cu(II), Ni(II) or Zn(II). The new compounds described here have been characterized by physical, spectral and analytical data, and have been screened for antibacterial activity against several bacterial strains such as Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa. The antibacterial potency of these Schiff bases increased upon chelation/complexation, against the tested bacterial species, opening new aproaches in the fight against antibiotic resistant strains.

scholarly journals Biologically Active Transition Metal Chelates of Ni(II), Cu(II) and Zn(II) With 2-Aminothiazole-Derived Schiff-bases: Their Synthesis, Characterization and the Role of Anions (NO3 , SO42− , C2O42- and CH3CO2− ) on Their Antibacterial Properties

1999 ◽  
Vol 6 (3) ◽  
pp. 187-192 ◽  
Author(s):  
Zahid H. Chohan
Keyword(s):  
Schiff Bases ◽  
Metal Ion ◽  
Bacterial Species ◽  
Analytical Data ◽  
Antibacterial Properties ◽  
Metal Chelates ◽  
Biologically Active ◽  
Transition Metal Chelates ◽  
Active Transition

Biologically active nickel(ll), copper(ll) and zinc(ll) chelates with thiazole-derived nitro- and chlorosalicylaldehyde Schiff-bases having the same metal ion but different anions, e.g. nitrate, sulfate, oxalate and acetate have been synthesized and characterized on the basis of their physical, spectral and analytical data. In order to evaluate the possible participating role of anions on the antibacterial properties, these ligands and their synthesized metal chelates with various anions have been screened against bacterial species Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus.

scholarly journals Pharmacological Role of Anions (Sulphate, Nitrate, Oxalate and Acetate) on the Antibacterial Activity of Cobalt(II), Copper(II) and Nickel(II) Complexes With Nicotinoylhydrazine-Derived ONO, NNO and SNO Ligands

1996 ◽  
Vol 3 (5) ◽  
pp. 211-217 ◽  
Author(s):  
Zahid Hussain Chohan ◽  
Abdur Rauf
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Metal Ion ◽  
Bacterial Species ◽  
Biologically Active ◽  
Schiff Base Ligands ◽  
Mixed Ligands ◽  
And Staphylococcus Aureus

Mixed ligands biologically active complexes of cobalt(II), copper(II) and nickel(II) with nicotinoylhydrazine-derived ONO, NNO and SNO donor schiff-base ligands having the same metal ion but different anions such as sulphate, nitrate, oxalate and acetate have been synthesised and characterised on the basis of their physical, analytical and spectral data. In order to evaluate the role of anions on their bioability, these ligands and their synthesised metal complexes with various anions have been screened against bacterial species such as Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus and the title studies have proved a definative role of anions in increasing the biological activity

scholarly journals Studies on Some Biologically Cobalt(II), Copper(II) and Zinc(II) Complexes With ONO, NNO and SNO Donor Pyrazinoylhydrazine-Derived Ligands

1998 ◽  
Vol 5 (5) ◽  
pp. 267-274 ◽  
Author(s):  
Zahid H. Chohan ◽  
Marapaka Praveen ◽  
Syed K. A. Sherazi
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antibacterial Activity ◽  
Bacterial Species ◽  
Analytical Data ◽  
Biologically Active ◽  
Activity Data ◽  
Distorted Octahedral ◽  
Physicochemical Studies

Biologically active complexes of Co(II), Ni(II), Cu(II) and Zn(II) with novel ONO, NNO and SNO donor pyrazinoylhydrazine-derived compounds have been prepared and characterized on the basis of analytical data and various physicochemical studies. Distorted octahedral structures for all the complexes have been proposed. The synthesized ligands and their complexes have been screened for their antibacterial activity against bacterial species Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Klebsiella pneumonae. The activity data show the metal complexes to be more active than the parent free ligands against one or more bacterial species.

Synthesis and Characterization of Palladium(II) Complexes with Substituted Dihydrobenzoimidazo Quinazoline Derivatives

2017 ◽  
Vol 13 (2) ◽  
pp. 1-15
Author(s):  
Rita Bhattacharjee Virupaiah Gayathri
Keyword(s):  
Metal Ion ◽  
Synthesis And Characterization ◽  
Planar Geometry ◽  
Conductivity Measurements ◽  
Spectral Techniques ◽  
Mass Spectral ◽  
Square Planar ◽  
Elemental Analyses ◽  
Quinazoline Derivatives

A series of palladium(II) halo complexes of the types [PdX 2 L 2 ].nH 2 O {n = 0, X = Cl, L = L 2 , L 4 and L 5 ; X = Br, L = L 2 ; n = 1, X = Cl, L = L 1 and L 3 } and Pd 2 X 4 L 3 [X = Br, L = L 1 , L 3 , L 4   and L 5 ] were prepared where L is 6-R-5,6- dihydrobenzoimidazo quinazoline (R-Diq; where R = ethyl: L 1 / n or i-propyl: L 2 , L 3 / n or i-butyl: L 4 , L 5 ) and characterized by elemental analyses, conductivity measurements, TGA, infrared, electronic, NMR and mass spectral techniques. Based    on these studies monomeric/dimeric structure with a square planar geometry around the metal ion was proposed for all the complexes. Some of the complexes were investigated for anti-microbial activity.

Metal Ion Complexes of Aromatic Amino Acids

1966 ◽  
Vol 21 (6) ◽  
pp. 522-526 ◽  
Author(s):  
J. Smith Decker ◽  
Herschel Frye
Keyword(s):  
Metal Ion ◽  
Analytical Data ◽  
Aromatic Amino Acids ◽  
Chlorobenzoic Acid ◽  
Solubility In Water ◽  
Nonpolar Solvents ◽  
Aminobenzoic Acids ◽  
Square Planar ◽  
Coordinated Water ◽  
Infrared Data

This study has shown that certain ring substitutions on aminobenzoic acids are possible without greatly affecting the favorable chelating properties of the parent ligand. It was also shown that para substitution of methyl groups yields more stable complexes than does ortho substitution relative to the amino group. Meta substitution of chlorine enhances chelate formation and yields very insoluble complexes in yields approaching one hundred per cent.Based on carbon-hydrogen analyses and other analytical data, the structures have been determined as square planar ones in which the ligand functions as a bidentate. Some water is usually incorporated in the crystal lattice, and occasionally a complex will contain one or more molecules of coordinated water. The variable amount of water in some compound crystals makes the carbonhydrogen data less exact and tends to obscure interpretation of at least some of the infrared data. Lack of solubility in water and in other polar and nonpolar solvents increases the difficulty of both infrared and ultraviolet-visible analyses; in every case potassium bromide tablets were made and were used in both infrared and ultraviolet-visible spectrophotometers; evidence obtained through study of the ultraviolet-visible data are not presented here, but there substantiate the data obtained by the other methods.With the ligands and metal cations used, fifty-five compounds were possible; forty-four of these were actually prepared and isolated, and of these, thirty-five were shown to be coordination complexes. Twenty-seven of these complexes were previously unreported including all the compounds reported for 3,5-dimethylanthranilic acid, 2-amino-4-chlorobenzoic acid, and 6-amino-3-methylbenzoic acid.

scholarly journals Synthesis, Characterization and Role of Anions (Nitrate, Sulphate, Oxalate and Acetate) \in the Biological Activity of Hydrazine Derived Compounds and Their Metal Chelates

1997 ◽  
Vol 4 (6) ◽  
pp. 327-332 ◽  
Author(s):  
Zahid H. Chohan ◽  
S. K. A. Sherazi
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Antibacterial Activity ◽  
Biological Activity ◽  
Metal Ion ◽  
Bacterial Species ◽  
Analytical Data ◽  
Metal Chelates

Hydrazine derived compounds and its Co(II), Cu(II) and Ni(II) chelates having the same metal ion but different anions (e.g., nitrate, sulphate, oxalate and acetate) have been synthesised and characterised by their physical, spectral and analytical data. In order to evaluate the participating role of anions in the antibacterial activity, these synthesised ligands and its metal chelates have been screened against bacterial species such as Staphylococcus aureous, pseudomonas aeruginosa, Klebsiella pneumonae and Proteus vulgarus, and the results are reported.

Complexes of palladium(II) with cis- and trans-1,2-bis(dimethylarsino)ethylene

1969 ◽  
Vol 47 (14) ◽  
pp. 2699-2706 ◽  
Author(s):  
G. J. Erskine
Keyword(s):  
Metal Ion ◽  
Room Temperature ◽  
Analytical Data ◽  
Far Infrared ◽  
Bridging Ligand ◽  
Dimeric Complexes ◽  
Square Planar ◽  
Temperature Irradiation ◽  
Cis And Trans ◽  
Cis Isomer

Palladium(II) complexes of cis- and trans-1,2-bis(dimethylarsino)ethylene, 1 and 2, respectively, in the metal: ligand ratios 1:1 and 1:2 are described. Their structures are discussed in terms of nuclear magnetic resonance, infrared, conductivity, and analytical data, and by comparison with the corresponding platinum(II) complexes (1). The cis-isomer, cis-ED, is a strong chelating ligand and forms the complexes Pd(cis-ED)X2, 9 (X = Cl−, Br−), and Pd(cis-ED)2X2•3H2O, 8 (X = Cl−, Br−, ClO4−, PF6−). The trans-isomer, trans-ED is a bridging ligand and forms the dimeric complexes, [Pd(trans-ED)X2]2, 10 (X = Cl−, Br−), and Pd2(trans-ED)4X4•3H2O, 7 (X = Cl−, Br−, ClO4−, PF6−). All these complexes contain 4-coordinate, square planar palladium(II). The anhydrous form of 7 (X = Cl−) shows evidence for a Pd—Cl bond, suggesting 5-coordination in the solid state. Room temperature irradiation (with ultraviolet light) of 7 (X = Cl−), in non-aqueous solvents, causes isomerization of the ligand and the formation of complex 8 (X = Cl−). No change occurs under these conditions in aqueous solutions. Contrary to the original suggestion for the corresponding platinum(II) derivative, 10 (M = Pt(II), ref. 1) far infrared evidence supports a cis-configuration about the metal ion rather than the trans-configuration, 6.

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