scholarly journals Synthesis, Identification, and Biological Study for Some Complexes of Azo Dye Having Theophylline

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Hasan Mohammed
Keyword(s):  
Azo Dye ◽  
Polar Solvent ◽  
Diazonium Salt ◽  
Octahedral Geometry ◽  
Biological Study ◽  
Infrared Spectrometry ◽  
Photochromic Properties ◽  
E Coli ◽  
Metal Ligand ◽  
Cobalt And Nickel

This article includes the synthesis of heterocyclic azo dye of theophylline by coupling diazonium salt of 4-chloroaniline with theophylline which is, namely, 8-(1-(4-chlorophenyl)azo)theophylline (CPAT). The complexes of cobalt and nickel were prepared by reacting their ions with CPAT ligand in ethanol under 1 : 2 ratio metal-ligand. The CPAT ligand and its complexes were characterized by elemental analysis, infrared spectrometry, electronic absorption spectroscopy, molar conductivity, and magnetic moment. The cobalt and nickel complexes show octahedral geometry having general formula [M(CPAT)2Cl2]. This article addresses the properties of CPAT dye such as photochromic properties. The CPAT dye exhibited obvious and desired changes under irradiation with visible light (405 nm), high sensitive for pH changes which refer to its ability to be analysis indicator. CPAT dye exhibited solvatochromic properties presenting red shift with polar solvent. The CPAT and its complexes show interesting antibiological activities towards Staph. aureus and E. coli bacteria and Aspergillus fungi.

scholarly journals Synthesis, Characterization and Microbial Evaluation of Heterocyclic Azo Dye Ligand Complexes of Some Transition Metal(II) Ions

2019 ◽  
Vol 31 (3) ◽  
pp. 727-732 ◽  
Author(s):  
Jinan Mohammed Mahmood Al-Zinkee ◽  
Amer J. Jarad
Keyword(s):  
Transition Metal ◽  
Azo Dye ◽  
Analytical Data ◽  
Octahedral Geometry ◽  
Condensation Rate ◽  
Biological Studies ◽  
Different Types ◽  
Metal Ligand ◽  
Azo Ligand

The snthesis and characterization of cobalt(II), nickel(II), copper(II) and zinc(II) complexes of azo ligand 4-[(5-acetyl-2-aminophenyl)-diazenyl]-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one derived from 4-aminoantipyrine and 4-aminoacetophenone are reported. The nature of the compounds have been studied followed by mole ratio and methods of continuous contrast, Beer′s law followed during a condensation rate (1 × 10-4 – 3 × 10-4 M). The analytical data showed that all the complexes are in 1:2 metal-ligand ratio. An octahedral geometry have been suggested for all the compounds and biological studies of all the complexes were evaluated against different types of antimicrobial strains.

Preparation of azo-dye sensitized TiO 2 photocatalyst for inhibition of E-Coli bacteria under visible light irradiation

2017 ◽  
Vol 4 (11) ◽  
pp. 11671-11678
Author(s):  
M. Giridhar ◽  
H.S. BhojyaNaik ◽  
R. Vishwanath ◽  
C.N. Sudhamani ◽  
M.C. Prabakar ◽  
...  
Keyword(s):  
Visible Light ◽  
Visible Light Irradiation ◽  
Azo Dye ◽  
Light Irradiation ◽  
E Coli ◽  
Dye Sensitized

Determination of Unconjugated and Total N-Acetyl-p-aminophenol (NAPA) in Urine and Serum

1967 ◽  
Vol 13 (3) ◽  
pp. 215-219 ◽  
Author(s):  
Karel P M Heirwegh ◽  
Johan Fevery
Keyword(s):  
Liver Disease ◽  
Acid Hydrolysis ◽  
Azo Dye ◽  
Acidic Medium ◽  
Diazonium Salt ◽  
Accurate Method ◽  
Total N ◽  
Hydrolysis Of ◽  
Urine And Serum

Abstract A sensitive and accurate method is described for the determination of N-acetyl-p-aminophenol (NAPA) and its metabolites in urine and serum. In strongly acidic medium, p-aminophenol (PAP) resulting from differential extraction and acid hydrolysis of total NAPA and unconjugated NAPA, is diazotized and the diazonium salt coupled with N-(1-naphthyl)ethylenediamine (NED) in the presence of ethanol. The blue azo dye formed is determined spectrophotometrically. Application to liver disease is briefly reported.

scholarly journals Spectrophotometric determination of metoclopramide hydrochloride in pharmaceutical tablets, by diazotization-coupling method with 1-naphthol as the coupling agent

2010 ◽  
Vol 7 (1) ◽  
pp. 704-712
Author(s):  
Baghdad Science Journal
Keyword(s):  
Detection Limit ◽  
Azo Dye ◽  
Diazonium Salt ◽  
Molar Absorptivity ◽  
British Pharmacopoeia ◽  
Pharmaceutical Tablets ◽  
Hydrochloric Acid Medium ◽  
Metoclopramide Hydrochloride ◽  
Sensitive Spectrophotometric Method

Simple, rapid and sensitive spectrophotometric method was proposed for the analysis of metoclopramide hydrochloride (MPH) in pure form as well as in pharmaceutical tablets. The method is based on the diazotization reaction of MPH with sodium nitrite in hydrochloric acid medium to form diazonium salt, which is coupled with 1-naphthol in sodium hydroxide medium to form azo dye, showing absorption maxima at 550 nm. Beer’s law is obeyed in the concentration range of 0.4 – 18 µg mL-1 of MPH with detection limit 0.5448 µg mL-1. The molar absorptivity and Sandell’s sensitivity are 3.4969 × 104 L mol-1 cm-1 and 0.0101 µg cm-2, respectively. The method was successfully applied to the determination of MPH in pharmaceutical tablets without any interference from common excipients used as additives in tablets. The results agree favorably with the official British Pharmacopoeia method.

A visible light mediated synergistic catalyst for effective inactivation of E. coli and degradation of azo dye Direct Red-22 with mechanism investigation

RSC Advances ◽  
2016 ◽  
Vol 6 (79) ◽  
pp. 75724-75735 ◽  
Author(s):  
Saraschandra Naraginti ◽  
Yi Li ◽  
Yunbo Wu
Keyword(s):  
Visible Light ◽  
Azo Dye ◽  
E Coli ◽  
First Time ◽  
Inactivation Of Bacteria ◽  
Co Doped ◽  
Degradation Of Azo Dye

Novel zirconium and silver co-doped TiO2 nanoparticles were fabricated and utilized as effective multifunctional visible light photocatalysts for inactivation of bacteria (E. coli) as well as degradation of azo dye (Direct Red-22) for the first time.

scholarly journals New Spectrophotometric Determination of Cefdinir by Batch Method and Cloud Point Extraction

2019 ◽  
Vol 30 (1) ◽  
pp. 85
Author(s):  
Omar Qusay Mezhir
Keyword(s):  
Detection Limit ◽  
Correlation Coefficient ◽  
Cloud Point ◽  
Azo Dye ◽  
Cloud Point Extraction ◽  
Diazonium Salt ◽  
Molar Absorptivity ◽  
Purple Colour ◽  
Beer's Law ◽  
Beer’S Law

In this study, new spectrophotometric methods were developed for estimation of cefdinir (CFD); the research consists of two methods. The first method depends on the conversion of function group amine in cefdinir to diazonium salt and then combined with the 2, 5-Dimethylphenol (2, 5-DMP) reagent in the alkaline medium. The formed azo dye has a purple colour with absorption intensity at λmax 510 nm. Concentration range was obeyed Beer's law at (1-50 μg / ml), correlation coefficient was 0.9998, molar absorptivity was 1.54 × 104 L.mol-1.cm-1 and the detection limit was 0.04 μg.ml-1. The second method is including cloud point extraction (CPE) of a trace amount of the formed azo dye in the first method followed by measuring with a UV-visible spectrophotometer. Concentration range that obeyed the Beer's law was (0.2-6 μg / ml), correlation coefficient was 0.9998, molar absorptivity was1.48×105 L.mol-1.cm-1, detection limit was 0.004 μg.ml-1, Pre-concentration factor was 25 and Distribution coefficient was 125.The proposed methods were applied and proved their compatibility for estimating of ingredient compound in pure samples and pharmaceuticals by comparing them with previous studies. Keyword: cefdinir, diazotization, cloud point extraction, 2, 5-Dimethylphenol.

scholarly journals Synthesis, Characterization and Biological Evaluation of Cr(III), Fe(III), Co(II), Ni(II), Zn(II) and Cd(II) Complexes Using an Azo Dye as Ligand

2020 ◽  
Vol 71 (6) ◽  
pp. 1-8
Author(s):  
Rana Abdulilah Abbas ◽  
Afnan E. Abd-Almonuim ◽  
Amer J. Jarad ◽  
Szidonia-Katalin Tanczos ◽  
Paul Constantin
Keyword(s):  
Magnetic Susceptibility ◽  
Carboxylic Acid ◽  
Atomic Absorption ◽  
Elemental Analysis ◽  
Azo Dye ◽  
Biological Evaluation ◽  
Octahedral Geometry ◽  
Spectroscopic Methods ◽  
Ft Ir ◽  
Azo Ligand

Azo ligand 11-(4-methoxyphenyl azo)-6-oxo-5,6-dihydro-benzo[4,5] imidazo[1,2-c] quinazoline-9-carboixylic acid was derived from 4-methoxyaniline and 6-oxo-5,6-dihydro-benzo[4,5]imidazo[1,2-c]quinazoline-9-carboxylic acid. The presence of azo dye was identified by elemental analysis and spectroscopic methods (FT-IR and UV-Vis). The compounds formed have been identified by using atomic absorption in flame, FT.IR, UV-Vis spectrometry magnetic susceptibility and conductivity. In order to evaluate the antibacterial efficiency of ligand and its complexes used in this study three species of bacteria were also examined. Ligand and its complexes showed good bacterial efficiencies. From the obtained data, an octahedral geometry was proposed for all prepared complexes.

scholarly journals Synthesis, Characterization and Antibacterial Study of Co (II) and Cu (II) Complexes of Sulfamethoxazole

2020 ◽  
pp. 38-43
Author(s):  
Usman Abubakar Adamu ◽  
Buhari Magaji ◽  
Adamu Baba Mohammad ◽  
Mukhtar Muhammad Sani ◽  
Nitte Adoram
Keyword(s):  
Electrical Conductivity ◽  
Elevated Temperature ◽  
Metal Complexes ◽  
Antimicrobial Agents ◽  
Polar Solvent ◽  
Free Ligand ◽  
Decomposition Temperature ◽  
Molar Ratio ◽  
Tetrahedral Geometry ◽  
E Coli

Complexes of Co and Cu with SMZ were successfully synthesized (1:2 molar ratio) in good yield and characterized by using UV-vis, FTIR, melting point/decomposition temperature, electrical conductivity and solubility in different solvents of varying polarity and proticity. All the prepared complexes were coloured. From the IR results, 529, 631, 528 and 779 cm-1 bands were observed in the spectra of the complexes which were absent in the free ligand spectrum thus, showing the presence of metal-ligand bond (coordination) in the complexes. The electronic spectral data of the complexes suggest an octahedral and tetrahedral geometry for all the complexes. The ligand and the Co (II) complex were found to be soluble polar protic solvents at both room and elevated temperature while, Cu (II) complex was found to be insoluble in polar protic solvent (ethanol) at room temperature but soluble at elevated temperature. The metal complexes are insoluble in non-polar solvent at both temperatures. More so, the ligand was found to be soluble in non-polar solvent at both temperatures. The electrical conductivity measurements indicated that the synthesized complexes are non-electrolytes. The synthesized metal complexes showed improved broad-spectrum antimicrobial activity against E. coli and S. aureus as compared to the ligand.  Thus, the complexes [Co(C10H11N3O3S)] and [Cu(C10H11N3O3S)] are good leads to be developed into antibiotics against the tested antimicrobial agents (E. coli and S. aureus).

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