scholarly journals Transcranial Magnetic Stimulation and Working Memory Training to Address Language Impairments in Aphasia: A Case Study

2021 ◽  
Vol 2021 ◽  
pp. 1-14
Author(s):  
Despina Kranou-Economidou ◽  
Maria Kambanaros
Keyword(s):  
Quality Of Life ◽  
Working Memory ◽  
Short Term Memory ◽  
Negative Impact ◽  
Memory Training ◽  
Computer Assisted ◽  
Language Therapy ◽  
Receptive Aphasia

Background. Traditionally, people with aphasia (PWA) are treated with impairment-based language therapy to improve receptive and expressive language skills. In addition to language deficits, PWA are often affected by some level of working memory (WM) impairments. Both language and working memory impairments combined have a negative impact on PWA’s quality of life. The aim of this study was to investigate whether the application of intermittent theta-burst stimulation (iTBS) combined with computerized WM training will result in near-ransfer effects (i.e., trained WM) and far-transfer effects (i.e., untrained language tasks) and have a positive effect on the quality of life of PWA. Methods. The participant was a 63-year-old Greek-Cypriot male who presented with mild receptive aphasia and short-term memory difficulties. Treatment was carried out using a multiple baseline (MB) design composed of a pretherapy or baseline testing phase, a therapy phase, and a posttherapy/follow-up phase. The treatment program involved iTBS application to the left dorsolateral prefrontal cortex (DLPFC), an area responsible for WM, for 10 consecutive sessions. The participant received a 3-minute iTBS application followed by 30-minute computer-assisted WM training. Outcome measures included a WM screening test, a standardized aphasia test, a nonverbal intelligence test, story-telling speech samples, a procedural discourse task, and a questionnaire addressing quality of life. These measures were performed three times before the treatment, immediately upon completion of the treatment, and once during follow-up testing at 3 months posttreatment. Results. We found a beneficial effect of iTBS and WM training on naming, reading, WM, reasoning, narrative, communication efficiency, and quality of life (QoL). Implications for Rehabilitation. Noninvasive brain stimulation combined with computerized WM training may be used in aphasia rehabilitation to improve WM and generalize to language improvement.

Adult CHD patients under clinical follow-up have a similar quality of life to the general population in Malta

2016 ◽  
Vol 27 (6) ◽  
pp. 1051-1059
Author(s):  
Maryanne Caruana ◽  
Victor Grech
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
General Population ◽  
Negative Impact ◽  
Adult Survivors ◽  
Cardiac Medication ◽  
Self Reporting Questionnaire ◽  
The Impact

AbstractBackgroundThe improved survival of patients born with CHD has led to increasing interest in research on quality of life of adult survivors. We report the findings of the first study in Malta carried out to investigate quality of life in adults with CHD under follow-up.MethodsA self-reporting questionnaire modelled on the basis of the European Health Interview Survey 2008, including questions on mental health and vitality, was administered to consecutive adult CHD outpatients, aged 16 years and over, between May, 2013 and May, 2014. Foreigners and patients with learning difficulties or cognitive impairment were excluded. Quality-of-life data were compared with that from 371 age- and sex-matched 2008 survey responders – general population cohort. The impact of congenital lesion complexity, hospitalisation in the preceding 12 months, arrhythmias, co-morbidities, and cardiac medication use on quality of life of the CHD cohort was also investigated.ResultsThere were a total of 120 patient responders (63 males; mean age 30.53, SD 12.77 years). Overall, there were no significant differences in mental health and vitality between patient and general population cohorts, although older patients had better mental health scores compared with age-matched controls. Within the adult CHD cohort, hospitalisation in the preceding 12 months was the only factor associated with a poorer quality of life.ConclusionsOverall, CHD has no negative impact on mental health and vitality in Maltese adult patients under follow-up. Patients needing frequent hospitalisations might warrant closer attention by clinical psychologists.

scholarly journals It is not only memory: effects of sensecam on improving well-being in patients with mild alzheimer disease

2017 ◽  
Vol 29 (5) ◽  
pp. 741-754 ◽  
Author(s):  
Ana Rita Silva ◽  
Maria Salomé Pinho ◽  
Luís Macedo ◽  
Christopher Moulin ◽  
Salomé Caldeira ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cognitive Rehabilitation ◽  
Affective State ◽  
Well Being ◽  
Memory Training ◽  
Depressive Symptomology ◽  
Rehabilitation Programs ◽  
Memory Rehabilitation

ABSTRACTBackground:Cognitive interventions (either restorative or compensatory) developed for mild Alzheimer's Disease (AD) have been tested widely with cognitive measures, but less is known about how the effects of such interventions are generalizable to daily functioning. In the present study, we looked at affective state and perceived functionality and quality of life indicators, for three different cognitive rehabilitation programs.Methods:Fifty-one AD patients in the mild stage of the disease were selected for the study and were randomly assigned to one of three cognitive training groups: (1) Memo+ (a paper and pencil memory training program); (2) SenseCam (wearable camera used as a passive external memory aid); (3) Written diary (a personal journal, used as control condition). All patients attended 11 sessions, twice a week, of 1-hour length. The three outcome indicators were examined with standardized instruments applied before the intervention, one week after and at six months follow-up.Results:After treatment, the SenseCam and Memo+ groups had significantly reduced depressive symptoms compared to the Diary control condition. The same was found for measures of perceived functional capacity. No intervention effects were found for quality of life measures. The immediate effects of the interventions were not maintained at follow-up.Conclusions:Our results suggest that two types of memory rehabilitation can improve depressive symptomology and instrumental activities of daily living, suggesting that these interventions can stimulate not only cognition but also well-being, at least in the short term.

scholarly journals IMPACT OF URINARY INCONTINENCE ON THE QUALITY OF LIFE AND FEMALE SEXUALITY

2010 ◽  
Vol 20 (1) ◽  
pp. 5
Author(s):  
B. Adile ◽  
P. Palma ◽  
A. Pollina ◽  
S. Bandiera ◽  
M.L. Amico ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Urinary Incontinence ◽  
Overactive Bladder ◽  
Female Sexuality ◽  
Negative Impact ◽  
Mixed Incontinence ◽  
International Consultation ◽  
Before And After

The prevalence of urinary incontinence is around 20% of healthy middle-aged women. Incontinence has a negative impact on quality of life and sexuality. From August 2002 to January 2004, 30 patients (mean age 43 years) with stress urinary incontinence (59%) overactive bladder (15%0) and mixed incontinence (26%) answered the ICIQSF (International Consultation on Incontinence Questionnaire – Short From) and FSFI (Female Sexual Function Index) questionnaires before and after treatment. The follow up ranged from 12 to 53 months. Mean ICIQ score was 17 and 7 before and after treatment respectively (p< 0,001). Overactive bladder showed the worst scores in all domains. The patients underwent surgery to increase desire (p=0,02), satisfaction (p=0,05) and t otal score (p=0,02). In 13 patients the ICIQ score did not increase: desire (p=0,01), satisfaction (p=0,05) and total score (p=0,01). Urinary incontinence significantly affects the quality of life. A sexuality evaluation in incontinence patients is recommended.

scholarly journals The Impact of Spondyloarthritis and Joint Symptoms on Health-Related Quality of Life and Fatigue in IBD Patients. Results From a Population-Based Inception Cohort (20-Year Follow-up in the Ibsen Study)

2019 ◽  
Vol 26 (1) ◽  
pp. 114-124 ◽  
Author(s):  
Alvilde Maria Ossum ◽  
Øyvind Palm ◽  
Milada Cvancarova ◽  
Tomm Bernklev ◽  
Jørgen Jahnsen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Negative Impact ◽  
Population Based ◽  
Patient Reported ◽  
Joint Symptoms ◽  
Related Quality ◽  
Health Related ◽  
The Impact

Ongoing joint pain and back pain were associated with reduced quality of life and fatigue in IBD patients after 20 years of disease, whereas spondyloarthritis without ongoing joint symptoms did not have a negative impact on these patient-reported outcomes.

scholarly journals The Impact of Chronic Inflammatory Enteropathy on Dogs’ Quality of Life and Dog-Owner Relationship

2021 ◽  
Vol 8 (8) ◽  
pp. 166
Author(s):  
Veronica Marchetti ◽  
Eleonora Gori ◽  
Valeria Mariotti ◽  
Angelo Gazzano ◽  
Chiara Mariti
Keyword(s):  
Quality Of Life ◽  
Negative Impact ◽  
Activity Index ◽  
Control Group ◽  
Clinical Activity ◽  
Chronic Enteropathies ◽  
Healthy Dogs ◽  
The Impact

This research was aimed at evaluating the impact of canine chronic enteropathies on dogs’ quality of life (QoL), their behavior, and owner–dog relationship. Forty-four dogs suffering from primary chronic enteropathies were assessed on the first visit with a veterinary gastroenterologist and on the first follow-up visit using a 1–10 visual scale to evaluate five features of QoL, the Canine Chronic Enteropathy Clinical Activity Index, the Lexington Attachment to Pet Scale, and the Canine Behavioral Assessment and Research Questionnaire. They were compared to a control group of 49 healthy dogs and to a group of 50 dogs suffering from cancer. QoL and severity of enteropathy were negatively associated; enteropathic dogs on the first visit had a lower QoL than healthy dogs for all features and a lower general QoL than cancer patients; enteropathic dogs on the follow-up visit improved significantly for general QoL, health QoL, and interaction QoL. Higher levels of attachment between the owner and the dog were obtained for dogs affected by chronic enteropathies. Finally, dogs showed higher scores for separation-related behaviors and contact/attention behaviors on the first visit than on the subsequent follow-up. As in human medicine, chronic enteropathies have a strong negative impact on dogs.

scholarly journals Evaluation of effectiveness of complex treatment of chronic generalized periodontitis using original splinting design

2021 ◽  
Vol 38 (6) ◽  
pp. 83-93
Author(s):  
N. B. Astashina ◽  
E. P. Rogozhnikova ◽  
A. S. Arutyunov ◽  
N. N. Malginov ◽  
S. V. Kazakov
Keyword(s):  
Quality Of Life ◽  
Comparison Group ◽  
Negative Impact ◽  
Young Patients ◽  
Pathological Process ◽  
Main Group ◽  
Complex Treatment ◽  
Periodontal Tissues

Relevance. The relevance of the study is dictated by the high prevalence of periodontal disease among young people and by the need to search for new approaches to periodontitis treatment in order to increase the effectiveness of treatment at early stages of pathological process. Objective. To evaluate the effectiveness of complex treatment of chronic generalized periodontitis (CGP) of mild severity using a removable splinting construction made according to the author's technique. Materials and methods. At the orthopedic stage of the complex treatment of mild CGP, splinting constructions were used for 47 young patients: in the main group (n = 16) the authors treatment and preventive splint, in the first comparison group (n = 15) a removable metal splint, in the second comparison group (n = 16) a fixed adhesive fiber splint. Periodontal hemodynamics was assessed using ultrasound Doppler analysis 1, 6 and 12 months after the therapeutic measures and tooth immobilization. To identify the possible negative impact of the treatment on the quality of life (QOL) in patients with splint constructions, we used the OHIP-14-Ru questionnaire; the follow-up period was 1.3, 6, and 12 months. Results. Dental immobilization contributed to the improvement of blood flow in the periodontal tissues in the short and long term follow-up, so after 12 months: Vam in the main group increased by 39,8 % and amounted to 0,397 0,004 cm / s, in patients of the comparison groups Vam was 0,329 0,006 cm / s and 0,335 0,003 cm / s, respectively, that is 15,4 % and 18,4 % higher compared with the figures before treatment. The quality of life index for patients using splinting constructions made according to the author's technique, by the OHIP-14-Ru questionnaire was assessed as good 1 year after (3.46 0.59). Conclusions. The use of the proposed original orthopedic design in a complex plan for mild periodontitis treatment helps to improve regional blood circulation and stabilize the pathological process.

scholarly journals QOL-06. QUALITY OF LIFE IN MEDULLOBLASTOMA SURVIVORS IN WESTERN MEXICO

2020 ◽  
Vol 22 (Supplement_3) ◽  
pp. iii432-iii432
Author(s):  
Regina M Navarro-Martin del Campo ◽  
Jorge L Macias-Toscano ◽  
Erika Toral-Casillas ◽  
Fernando Sánchez-Zubieta ◽  
Ana L Orozco-Alvarado
Keyword(s):  
Quality Of Life ◽  
Functional State ◽  
Clinical Data ◽  
Negative Impact ◽  
Hormone Replacement ◽  
Academic Development ◽  
Western Mexico

Abstract BACKGROUND Treatment of children with medulloblastoma (MB) can lead survivors to lidiate with long term sequelae and affect their quality of life (QoL). This study evaluates QoL in long term MB survivors. DESIGN/ METHODS Clinical files of MB survivors from 1997 to 2016 were retrospectively analyzed. QoL was defined by Schipper Criteria in a five dimensional evaluation: clinical data, physic effects of treatment, academic develop, functional state and self welfare report. RESULTS Clinical data: Twenty eight survivors were identified, mean age at review was 18 years, median follow up was 106 months. Functional state: Last visit Karfnosky/lansky were 90 to 80% in 25% of patients. Physic effects of treatment: Cerebellar Mutism or ataxia were present in 25% of cases. Two patients required external dispositives. Audiometry detected an auditive tonal decrease in 25% of cases. An endocrine disfunction was present in 46% of cases, 32% required hormone replacement and 28% having short size. Renal damage without dialysis was detected in 7% and 10% had a transient tubulopaty. One case had bilateral amaurosis and 14% uses glasses. Three patients had a life partner. One female has offspring and two males had azoospermia. Academic development: While 90% attends to school, 35.7% complained of learning difficulties and 18% needed special education. Self welfare report: Difficulties in social environment were described in 21% and 14% still feeling sick during years. CONCLUSIONS Survivors of MB had adverse physical effects, followed by academic development, functional state and self welfare report and all this has a negative impact in their QoL.

scholarly journals Time-Limited Eating and Continuous Glucose Monitoring in Adolescents with Obesity: A Pilot Study

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 3697
Author(s):  
Alaina P. Vidmar ◽  
Monica Naguib ◽  
Jennifer K. Raymond ◽  
Sarah Jeanne Salvy ◽  
Elizabeth Hegedus ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Weight Loss ◽  
Pilot Study ◽  
Continuous Glucose Monitoring ◽  
Eating Behaviors ◽  
Negative Impact ◽  
Glucose Monitoring

Due to its simplicity, time-limited eating (TLE) may represent a more feasible approach for treating adolescents with obesity compared to other caloric restriction regimens. This pilot study examines the feasibility and safety of TLE combined with continuous glucose monitoring (CGM) in adolescents. Fifty adolescents with BMI ≥95th percentile were recruited to complete a 12-week study. All received standard nutritional counseling, wore a CGM daily, and were randomized to: (1) Prolonged eating window: 12 h eating/12 h fasting + blinded CGM; (2) TLE (8 h eating/16 h fasting, 5 days per week) + blinded CGM; (3) TLE + real-time CGM feedback. Recruitment, retention, and adherence were recorded as indicators of feasibility. Weight loss, dietary intake, physical activity, eating behaviors, and quality of life over the course of the intervention were explored as secondary outcomes. Forty-five participants completed the study (16.4 ± 1.3 years, 64% female, 49% Hispanic, 75% public insurance). There was high adherence to prescribed eating windows (TLE 5.2 d/wk [SD 1.1]; control 6.1 d/wk [SD 1.4]) and daily CGM wear (5.85 d/wk [SD 4.8]). Most of the adolescents (90%) assigned to TLE reported that limiting their eating window and wearing a CGM was feasible without negative impact on daily functioning or adverse events. There were no between-group difference in terms of weight loss, energy intake, quality of life, physical activity, or eating behaviors. TLE combined with CGM appears feasible and safe among adolescents with obesity. Further investigation in larger samples, with a longer intervention duration and follow-up assessments are needed.

scholarly journals Questionnaire-based evaluation of satisfaction levels in patients receiving chemotherapy through implanted venous access ports

2020 ◽  
Vol 7 (6) ◽  
pp. 509-514
Author(s):  
Nilgün Yıldırım ◽  
Mahir Cengiz ◽  
Erhan Önalan ◽  
Sibel Özcan ◽  
Azmi Lale
Keyword(s):  
Quality Of Life ◽  
Negative Impact ◽  
Venous Access ◽  
Port Catheter ◽  
Face To Face ◽  
Significant Difference ◽  
A Minor ◽  
Implantation Procedure

Objective: This study aimed to evaluate the effect of totally implanted venous access ports on the quality of life and patient satisfaction of cancer patients. Materials and Methods: The study was comprised of patients who underwent implantation of a central venous port catheter (CVPC) for chemotherapy treatment at our hospital’s oncology department and continued with follow-up and treatment. The researchers conducted face-to-face interviews with the participants in which the latter responded to 15 questions concerning the effects of the port catheter on daily quality of life and satisfaction with the implantation procedure. Results: A total of 260 patients participated in the study. Port-related complications were observed in 54 patients (20.7%), the most common being catheter occlusion. Participants expressed high levels of satisfaction and stated that the CVPC had a positive effect on their quality of life. Overall satisfaction and quality of life were significantly different for patients who experienced complications compared to those without, however, with the former reporting decreased satisfaction and increased stress and anxiety levels. Nevertheless, there was no significant difference between the patients who developed complications and those who did not concern their response to the statement: “Faced with a similar situation requiring a port catheter, I would make the same decision" (54.5% versus 52%, p = .188). Conclusion: Most patients reported overall satisfaction with the CVPC system while noting a minor negative impact on daily life. Complications related to the implantation procedure have statistically been shown to be a predictor of satisfaction and quality of life.

scholarly journals Quality of life issue in psoriasis: A study from western Nepal

2015 ◽  
Vol 3 (2) ◽  
pp. 116-120
Author(s):  
A Kumar ◽  
S Neupane ◽  
PR Shrestha ◽  
J Pun ◽  
P Thapa ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Negative Impact ◽  
Severity Index ◽  
Cross Sectional Study ◽  
Psoriasis Area Severity Index ◽  
Cross Sectional ◽  
Psoriasis Disability Index ◽  
Chisquare Test

Background: Psoriasis may have negative impact on a patient’s quality of life. Very few studies have examined this aspect in Nepalese population. Aim of this study was to evaluate the Quality of life (QOL) in chronic psoriatic patients by modified version of psoriasis disability index (PDI).Methods: Present cross sectional study was conducted in three major hospitals in western Nepal. One hundred chronic psoriatic patients of 18 years or more of age, with disease duration of six months or more and body surface area involvement of 10% or more were recruited. Clinical assessment was done with psoriasis area severity index (PASI) and quality of life was measured by modified version of PDI. Patients were managed as per indication. At the follow up at four weeks, improvement in PASI and improvement in QOL was measured. Statistical analysis by Chisquare test was done to assess the relation between severity of psoriasis and different items of quality of life.Results: Psoriasis has negative impact on all aspect of quality of life in Nepalese patients, as shown by score of modified version of PDI, which was 39.27% of total. There was significant improvement in PASI at follow up visit, from 23.29% to 15.35% of total. There was significant improvement in quality of life after treatment (modified version of PDI) from 39.27% to 32.66% of total.Conclusions: Psoriasis has negative impact on all aspect of quality of life in Nepalese patients.Nepal Journal of Medical Sciences Vol.3(2) 2014: 116-120

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