scholarly journals A Novel Approach to the Symptomatic Management of Chronic Megacolon

2021 ◽  
Vol 2021 ◽  
pp. 1-3
Author(s):  
Michelle J. Ward
Keyword(s):  
Rare Condition ◽  
Abdominal Distension ◽  
Rectal Tube ◽  
Oral Nutrition ◽  
Electrolyte Disturbances ◽  
Novel Approach ◽  
Symptomatic Management

Background. Chronic megacolon is a rare condition which primarily occurs in patients with autonomic dysfunction of a variety of causes. Its management is often challenging and people with chronic megacolon often suffer from abdominal distension, pain, and malabsorption. Given the struggles clinicians experience in managing these patients long term, this case study provides an example of an alternate strategy for the symptomatic management of chronic megacolon. Case Description. An 80-year-old male with early Parkinson’s disease developed megacolon following a basal ganglia stroke. He had a protracted hospital stay over 6 months due to malabsorption requiring total parenteral nutrition and electrolyte disturbances. A trial of subcutaneous neostigmine was unsuccessful, so patient underwent a trial of intermittent rectal tube decompression which improved his symptoms and malabsorption. This technique was then taught to the patient’s wife until she was confident performing this herself. With continuation of decompression approximately every three days, the patient was able to return to oral nutrition and no longer required ongoing electrolyte replacement. He was able to be discharged into the community with significant improvement in his quality of life. Conclusion. This is the first report to suggest the benefit of intermittent rectal tube decompression in the community for the long-term management of chronic megacolon. Further prospective studies should evaluate the potential for this strategy to be implemented in a wider cohort of patients who are not responsive to existing treatments for chronic megacolon.

A ROLE OF AYURVEDA IN THE MANAGEMENT OF APASMARA (EPILEPSY): A CASE STUDY

2021 ◽  
Vol 12 (4) ◽  
pp. 24-29
Author(s):  
Shruti . ◽  
C V Rajashekhar ◽  
Manjunatha Adiga
Keyword(s):  
Antiepileptic Drugs ◽  
Palliative Treatment ◽  
Cognitive Level ◽  
Frequent Seizure ◽  
Seizure Attack ◽  
Seizure Attacks

Apasmara (epilepsy) is defined as the apagama (deterioration) of smriti (memory) associated with bibhasta cheshta (seizures) due to derangement of dhi and satwa, mainly related to vata and rajo dosha vitiation, which effects both Sharira (body) and Mana (mind). The present antiepileptic drugs control the seizure attack, but long-term use generates adverse effect at cognitive level and leads to behavioral disorders, hence there is need of safe and effective treatment which not only controls seizure attack but helps to cure the disease. A 44-year-old man approached Kayachikitsa OPD with the complaints of frequent seizure attacks, since from at the age of one and half year with regular oral antiepileptic drugs medications (allopathic), the dose of medications increasing yearly and he was not satisfied with treatment, so he was advised with Panchakarma treatment starting from Deepana, Pachana, Vamana (medicated emesis), Virechana (medicated purgation), Basti (medicated enema), Shirodhara along with palliative treatment. After each treatment it was observed that the patient was satisfied with treatment and the complaints of seizure attack reduced in frequency and duration with improved quality of life. Palliative treatment was advised to continue along with modern medications.

scholarly journals A Novel Approach for the Reimbursement of Permanent Partial Dental Disability Following Dental Injury

2015 ◽  
Vol 16 (6) ◽  
pp. 504-506
Author(s):  
Edgar Nehme ◽  
Sami Jad
Keyword(s):  
Quality Of Life ◽  
Insurance Companies ◽  
Court System ◽  
Permanent Disability ◽  
Dental Injury ◽  
System A ◽  
Novel Approach ◽  
New Formula

ABSTRACT Reimbursement of long-term permanent disability following a dental injury can lead to claims and legal involvement by the injured person. This will delay the treatment the patient's quality of life and the court system. A new formula has been hypothesized to address the problem. This might help the stakeholders including patients, insurance companies. The details of calculating the index and its significance are discussed. Implication studies are mandatory to refine the proposed hypothesis. How to cite this article Ayoub F, Nehme E, Jad S, Salameh Z. A Novel Approach for the Reimbursement of Permanent Partial Dental Disability Following Dental Injury. J Contemp Dent Pract 2015;16(6):504-506.

scholarly journals Lessons For Toronto From Melbourne’s City Centre Revitalization

2021 ◽  
Author(s):  
Brent Gilliard
Keyword(s):  
Public Space ◽  
Public Life ◽  
Public Spaces ◽  
City Centre ◽  
Physical Quality ◽  
Social Quality

Public space is important to a city’s economic and social quality. Downtown Toronto is not known for its public spaces but Melbourne is widely recognized for recently revitalizing its city centre with improved public spaces. A case study of Melbourne investigates its comparability to Toronto as well as the details of its "renaissance." It is concluded that Melbourne is, in fact, highly comparable to Toronto. Interventions in Melbourne were characterized by the principles: long-term vision, emphasizing local strengths, investment in quality, making space for people on foot, and using effective arguments and evidence. To emulate Melbourne’s city-centre revitalization, Toronto first should facilitate a civic conversation about the long-term vision for its downtown; second, it should initiate a public life survey of the downtown; third, it should invest is the physical quality of downtown public spaces; and fourth, it should begin an incremental program to reclaim roadway space from cars in locations of high pedestrian use.

scholarly journals Radio Planning Considerations in TETRA to LTE Migration for PPDR Systems: A Radioelectric Coverage Case Study

2019 ◽  
Vol 9 (2) ◽  
pp. 250 ◽  
Author(s):  
Diego del Rey Carrión ◽  
Leandro Juan-Llácer ◽  
José-Víctor Rodríguez
Keyword(s):  
Radio Communications ◽  
The Real ◽  
Lte Network ◽  
Real Scenario ◽  
The Cost ◽  
Areas Of Interest ◽  
Radio Planning

Transitioning a Terrestrial Trunked Radio (TETRA) network to a Long-Term Evolution (LTE) network in public protection and disaster relief (PPDR) systems is a path to providing future services requiring high radio interface throughput and allowing broadband PPDR (BB-PPDR) radio communications. Users of TETRA networks are currently considering how to deploy a BB-PPDR network in the coming years. This study offers several radio planning considerations in TETRA to LTE migration for such networks. The conclusions are obtained from a case study in which both measurements and radioelectric coverage simulations were carried out for the real scenario of the Murcia Region, Spain, for both TETRA and LTE systems. The proposed considerations can help PPDR agencies efficiently estimate the cost of converting a TETRA network to an LTE network. Uniquely in this study, the total area is divided into geographical areas of interest that are defined as administrative divisions (region, municipal areas, etc.). The analysis was carried out using a radio planning tool based on a geographic information system and the measurements have been used to tune the propagation models. According to the real scenario considered, the number of sites needed in the LTE network—for a specific quality of service (90% for the whole region and 85% for municipal areas)—is a factor of 2.4 higher than for TETRA network.

scholarly journals Complex regional pain syndrome secondary to sacrococcygeal dislocation following trauma to the lumbosacral region. Case report

Case reports ◽  
2020 ◽  
Vol 6 (1) ◽  
pp. 52-62
Author(s):  
Iván Torres-Salguero ◽  
Andrés Mariano Rubiano
Keyword(s):  
Quality Of Life ◽  
Clinical Presentation ◽  
Functional Limitation ◽  
Rare Condition ◽  
Pain Syndrome ◽  
Cns Involvement ◽  
Lumbosacral Region ◽  
Vasomotor Dysfunction

Introduction: The complex regional pain síndrome (CRPS) is a rare condition characterized by inflammatory, vasomotor and central nervous system (CNS) involvement. Its clinical presentation can be subacute, acute or chronic, and may have severe effects on the patient’s quality of life.Case description: 21-year-old female patient with trauma in the lumbosacral region associated with pain and functional limitation. Diagnostic imaging showed sacrococcygeal dislocation with subsequent inflammatory and acute and chronic autonomic symptoms that were treated medically and surgically. The patient responded to treatment with long-term improvement of the symptoms.Discussion: In this case, CRPS occurred after trauma and caused subacute symptoms that became even more acute until reaching a chronic presentation. Inflammation, vasomotor dysfunction and CNS involvement made this case a multidisciplinary diagnostic and therapeutic challenge.Conclusion: CRPS is a rare disease that is difficult to diagnose. However, diagnosis should be timely in order to initiate personalized treatment, since this disease considerably affects the patient’s quality of life.

scholarly journals Alternatives to groundwater abstraction as a measure to stop land subsidence: a case study of Semarang, Indonesia

2019 ◽  
Vol 125 ◽  
pp. 01003 ◽  
Author(s):  
Wesley Beek ◽  
Bart Letitre ◽  
H. Hadiyanto ◽  
S. Sudarno
Keyword(s):  
Cost Benefit Analysis ◽  
Cost Benefit ◽  
Drinking Water Treatment ◽  
Decision Makers ◽  
Groundwater Abstraction ◽  
Short Term ◽  
Treatment Services

The Water as Leverage project aims to lay a blueprint for urban coastal areas around the world that are facing a variety of water-related issues. The blueprint is based upon three real case studies in Bangladesh, India and Indonesia. The case of Indonesia focuses on Semarang, a city that faces issues like flooding, increased water demand, and a lack of wastewater treatment. In this report I summarise the different techniques available to tackling these issues. Along with this I provide a cost-benefit analysis to support decision makers. For a short term it is recommended to produce industrial water from (polluted) surface water as a means to offer an alternative to groundwater abstraction. On a long term it is recommended to install additional wastewater and drinking water treatment services to facilitate better hygiene and a higher quality of life.

scholarly journals Intravenous Honokiol in Drug-Resistant Cancer: Two Case Reports

2020 ◽  
Vol 19 ◽  
pp. 153473542092261
Author(s):  
Isaac Eliaz ◽  
Elaine Weil
Keyword(s):  
Drug Resistance ◽  
Cancer Patients ◽  
Complete Blood Count ◽  
Case Reports ◽  
Clinical Results ◽  
Drug Resistant ◽  
Magnolia Officinalis

Context: Long-term patient survival in cancer is affected by drug resistance. Honokiol (HNK) is a small-molecule polyphenol isolated from the bark and seed cones of Magnolia officinalis. HNK has been shown to enhance the effects of chemotherapy and inhibit drug resistance in preclinical models. HNK was well tolerated in multiple animal models when administered orally, intravenously (IV), and via intraperitoneal route. However, there are limited human data on the use of HNK in general, and specifically via IV (HNK-IV) in cancer. Objective: We aim to assess the efficacy, safety, and tolerability of HNK-IV in patients with drug-resistant tumors. Methods: This is a case study of 2 cancer patients who utilized HNK-IV as part of their cancer treatment regimen. The initial infusion of HNK was 10 mg/kg body weight, and subsequent treatments were increased up to 50 mg/kg according to individual tolerance, over 2 weeks. Results: Positive clinical response was achieved in both patients, including improved symptoms and quality of life. No serious adverse side effects occurred, and there were no adverse effects on laboratory parameters (complete blood count, kidney, and liver function). Transient sedation and minor nausea were noted and resolved postinfusion. Conclusions: This is the first report of HNK-IV in human patients. Given the positive clinical results, safety, and tolerability, the use of HNK-IV warrants further investigation regarding optimum formulation, and its use as adjunctive therapy in cancer patients.

A Novel Approach to Monitoring the Quality of Lakes Water by Optical and Modeling Tools: Lake Sevan as a Case Study

2020 ◽  
Vol 231 (8) ◽  
Author(s):  
Costas A. Varotsos ◽  
Vladimir F. Krapivin ◽  
Ferdenant A. Mkrtchyan ◽  
Suren A. Gevorkyan ◽  
Tengfei Cui
Keyword(s):  
Modeling Tools ◽  
Lake Sevan ◽  
Novel Approach

Multiple Aplasia Cutis Congenita Lesions of the Scalp: A Case Study

2020 ◽  
Vol 39 (2) ◽  
pp. 83-91
Author(s):  
Mary Whalen
Keyword(s):  
Chromosomal Abnormalities ◽  
Rare Condition ◽  
Trisomy 13 ◽  
Aplasia Cutis Congenita ◽  
Live Births ◽  
Patau Syndrome ◽  
Males And Females ◽  
Aplasia Cutis

Aplasia cutis congenita (ACC) is a rare condition that presents at birth as an absence of skin that does not usually involve underlying structures. Occurring in 3/10,000 live births, ACC is evenly distributed between males and females; the risk of ACC increases to 7 percent in consanguineous marriages. Up to 86 percent of lesions are found on the scalp in the midline vertex position. Lesions can also be found on the trunk and limbs, as with Adams-Oliver syndrome or accompanying epidermolysis bullosa. ACC is associated with chromosomal abnormalities and 35–50 percent of the time with trisomy 13 (Patau syndrome). This case study presents an infant with multiple ACC lesions of the scalp. The pathophysiology, treatment, potential long-term complications, and nursing considerations are discussed.

scholarly journals Tradition and Modernity in the Romanian Rural Space. Case Study: the Arges Sub-Carpathian Foothills

2013 ◽  
Vol 19 (1) ◽  
pp. 127-151 ◽  
Author(s):  
Gabriela Manea ◽  
Elena Matei ◽  
Iuliana Vijulie ◽  
Marian Marin ◽  
Octavian Cocos ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Spiritual Values ◽  
Rural Settlements ◽  
Rural Space ◽  
Goods And Services ◽  
Space Case ◽  
Geographical Space

Abstract This paper intends to demonstrate on the basis of a case study that rural people’s access to modern goods and services is not necessarily a relentless source of deculturalisation, because it sometimes allows a better management and valorisation of the main characteristics of the rural space. Despite socio-economic unrest and successive changes of political regimes that took place in Romania during the last century, the human communities within the Arges foothills have defended with dignity their traditional material and spiritual values, passing them down from generation to generation. In the medium and long-term, the valorisation of the Romanian rural space, in general, and of that belonging to the Arges foothills, in particular, will imply the creation of a balance between the valuable cultural potential and the quality of life of the inhabitants, who are the keepers of rural cultural heritage. At present, the best thing to do to pass on the traditions of this area is to proudly accept the affiliation to this geographical space. This is true not only for the permanent inhabitants of rural settlements, but mostly for those who have left the countryside to carry it in their minds and souls. In our opinion, this fact is a pre-requisite for preventing the loss of material and spiritual values of this cultural-historical space.

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